Fasting as Medicine: Mitochondrial and Endothelial Rejuvenation in Vascular Aging
Aging Cell, Volume 25, Issue 2, February 2026.Aging impairs cerebrovascular health by driving mitochondrial dysfunction, oxidative stress, endothelial failure, and neurovascular uncoupling, leading to BBB breakdown and cognitive decline. In contrast, time‐restricted feeding/eating counteracts these mechanisms by restoring mitochondrial function, activating adaptive nutrient‐sensing pathways ...
Madison Milan +13 more
wiley +1 more source
Post hoc analyses of surrogate markers of non-alcoholic fatty liver disease (NAFLD) and liver fibrosis in patients with type 2 diabetes in a digitally supported continuous care intervention: An open-label, non-randomised controlled study [PDF]
, 2018 OBJECTIVE: One year of comprehensive continuous care intervention (CCI) through nutritional ketosis improves glycosylated haemoglobin(HbA1c), body weight and liver enzymes among patients with type 2 diabetes (T2D).
Adams, Rebecca N +10 more
core +2 more sources
Diabetes, Obesity and Metabolism, Volume 28, Issue 2, Page 826-839, February 2026.Abstract Maternally inherited diabetes and deafness (MIDD) is a mitochondrial disorder usually caused by the variant m.3243A>G in the MT‐TL1 gene. We have proposed that diabetes in MIDD arises from a combination of insulin resistance and impaired β‐cell function that is more likely to occur in the presence of high skeletal muscle heteroplasmy and ...
Ahsen Chaudhry +2 more
wiley +1 more source
The Effects of Carbohydrate, Unsaturated Fat, and Protein Intake on Measures of Insulin Sensitivity: Results from the OmniHeart Trial [PDF]
, 2014 OBJECTIVE Impaired insulin sensitivity increases the risk of cardiovascular disease. Although calorie restriction and weight loss increase insulin sensitivity, the effects of modifying macronutrient composition on insulin sensitivity are uncertain.
Anderson, Cheryl A.M. +5 more
core +1 more source
International Journal of Molecular Sciences, 2020 Gut microbiota is well known as playing a critical role in inflammation and asthma development. The very low-calorie ketogenic diet (VLCKD) is suggested to affect gut microbiota; however, the effects of VLCKD during pregnancy and lactation on the infant ...
Naser A. Alsharairi
semanticscholar +1 more source
Impacts of Diets and Food Plans in Health and Diseases—A Narrative Review
Food Safety and Health, Volume 4, Issue 1, Page 31-49, January 2026.This review emphasizes different diet types, providing insights into their nutritional content and health effects. Vegetarian and vegan diets, ketogenic diets, Mediterranean diets, Western diets, pescatarian diets, flexitarian diets, and territorial diversified diets are discussed, highlighting their influences on health, and diseases.
Md. Mahbubar Rahman +3 more
wiley +1 more source
Chronotype as a predictor of weight loss and body composition improvements in women with overweight or obesity undergoing a very low-calorie ketogenic diet (VLCKD) [PDF]
, 2023 Ludovica Verde +5 more
openalex +1 more source
Mitigation of Metabolic Diseases Through Personalized Nutrition: A Critical In‐Depth Review
Food Science &Nutrition, Volume 14, Issue 1, January 2026.The main objective of this review is to explore the impact of variation within the microbiome and among genes on nutrient metabolism and argue in favor of successful evidence of individualized dietary intervention for cardiovascular disease, diabetes, and obesity.
Muhammad Tayyab Arshad +7 more
wiley +1 more source
Effects of a ketogenic mediterranean diet on physiological and psychological variables [PDF]
, 2017 Ketogenic diets (KDs) are diets in which the net carbohydrate intake, calculated by subtracting fibres from total carbohydrates, is between 20 and 50 g/day (
Lodi, Alessandra
core +1 more source
Impact of a 6-week non-energy-restricted ketogenic diet on physical fitness, body composition and biochemical parameters in healthy adults [PDF]
, 2017 BACKGROUND: The ketogenic diet (KD) is a very low-carbohydrate, high-fat and adequate-protein diet that without limiting calories induces different metabolic adaptations, eg, increased levels of circulating ketone bodies and a shift to lipid metabolism ...
Anja Wehrle +5 more
core +1 more source