Results 151 to 160 of about 147,523 (312)

Heterogeneity of human very low density lipoproteins by gel filtration chromatography

open access: hybrid, 1972
Steven H. Quarfordt   +3 more
openalex   +1 more source

Protein Spatial Structure Meets Artificial Intelligence: Revolutionizing Drug Synergy–Antagonism in Precision Medicine

open access: yesAdvanced Science, EarlyView.
This review comprehensively examines the applications of protein three‐dimensional structures and artificial intelligence in investigating drug synergistic and antagonistic effects. The research findings provide compelling evidence for the precision treatment of cancer and metabolic diseases, thereby promoting the development of personalized medicine ...
Anqi Lin   +11 more
wiley   +1 more source

Artificial Internalizing Receptors for Targeted Degradation of Extracellular Proteins

open access: yesAdvanced Science, EarlyView.
Small organic molecules that are anchored into the lipid bilayer of a mammalian cell and have an exofacial recognition ligand can act as artificial internalizing receptors. These receptors are an efficacious tool to selectively capture and internalize cognate antibodies from the extracellular environment in a protein‐specific manner.
Ane B. Søgaard   +3 more
wiley   +1 more source

Effects of TM6SF2 E167K on hepatic lipid and very low-density lipoprotein metabolism in humans. [PDF]

open access: yesJCI Insight, 2020
Borén J   +14 more
europepmc   +1 more source

Hologenomics Reveals Specialized Dietary Adaptations in the Mengla Snail‐Eating Snake

open access: yesAdvanced Science, EarlyView.
Dietary adaptation studies from a holobiome perspective are scarce beyond mammals. This research reveals how genomic and microbial interactions drive dietary specialization in the Mengla snail‐eating snake, with evidence of gut symbiont convergence between reptiles and mammals.
Chaochao Yan   +10 more
wiley   +1 more source

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