Results 171 to 180 of about 531,046 (373)

Palmitoylation‐Mediated Ubiquitination of SRPK1 Regulates Ferroptosis in High‐Fat‐Induced Erectile Dysfunction

Advanced Science, EarlyView.
Elevated exogenous palmitic acid promotes the S‐palmitoylation of SRPK1 in endothelial cells, a dynamic process governed by ZDHHC24 and APT1. This post‐translational modification strengthens the interaction between SRPK1 and the E3 ubiquitin ligase MIB1, thereby facilitating the proteasomal degradation of SRPK1.
Xiao‐Hui Tan, Ke‐Fan Li, Yi‐Ming Yuan, Man‐Cheng Xia, Fang‐Zhou Zhao, Hong‐Gang Ying, Zhuo Zhou, Peng‐Chao Gao, Guo‐Qing Xie, Xue‐Song Li, Hui Jiang, Rui‐Li Guan   +11 more
wiley   +1 more source

Hyperlipidaemia elicits an atypical, T helper 1-like CD4⁺ T-cell response: a key role for very low-density lipoprotein. [PDF]

Eur Heart J Open, 2023
van Os BW, Vos WG, Bosmans LA, van Tiel CM, Lith SC, den Toom MS, Beckers L, Levels JHM, van Wouw SAE, Zelcer N, Zaal EA, Berkers CR, van der Lest CHA, Helms JB, Weber C, Atzler D, de Winther MPJ, Baardman J, Lutgens E.   +18 more
europepmc   +1 more source

Artemisia Iwayomogi Extract Attenuates High-Fat Diet-Induced Hypertriglyceridemia in Mice: Potential Involvement of the Adiponectin-AMPK Pathway and Very Low Density Lipoprotein Assembly in the Liver [PDF]

, 2017
Jinhui Lee, Vikram P. Narayan, Eun Hong, Wan Kyunn Whang, Taesun Park   +4 more
openalex   +1 more source

APOE‐stratified Proteomic and Metabolomic Analysis Reveals Mitochondrial Dysfunction Inflammation and Lipid Dysregulation in Alzheimer's Disease

Advanced Science, EarlyView.
A large‐scale multiomic dataset (proteomic and metabolomic) comprising 3,060 plasma samples were analyzed to identify proteins, metabolites, pathways, and protein‐associated drugs linked to Alzheimer’s Disease (AD) independently of apolipoprotein E (APOE). AD was associated with a distinct molecular signature that captures.
Fuhai Li, Yike Chen, Daniel Western, Muhammad Ali, Menghan Liu, Katherine Gong, Ying Xu, Joseph Lowery, David M. Holtzman, Chloe Robins, John D. Eicher, Yen‐Ning Huang, ShiWei Liu, Tamina Park, Andrew J. Saykin, Kwangsik Nho, Mahdi Moqri, Richard C. Mohs, Amelia Farinas, Patricia Moran‐Losada, Hamilton Se‐Hwee Oh, Tony Wyss‐Coray, Carlos Cruchaga   +22 more
wiley   +1 more source

Effect of Dyslipidaemia and Metabolic Function in Coronary Heart Disease with Type 2 Diabetes Mellitus - In Tertiary Care Center

Journal of Pharmacy and Bioallied Sciences
Introduction: T2DM is strongly associated with an increased prevalence of cardiovascular disease (CVD). It has been established that CVD is the main cause of mortality among patients with type 2 diabetes mellitus (T2DM) contributing to 80% of fatal ...
Akansha Singh, Ranjit S. Ambad, Roshan Kumar Jha   +2 more
doaj   +1 more source

Soluble very low-density lipoprotein receptor (sVLDLR) inhibits fibrosis in neovascular age-related macular degeneration. [PDF]

FASEB J, 2021
Ma X, Takahashi Y, Wu W, Chen J, Dehdarani M, Liang W, Shin YH, Benyajati S, Ma JX.   +8 more
europepmc   +1 more source

Steatohepatitis and liver fibrosis are predicted by the characteristics of very low density lipoprotein in nonalcoholic fatty liver disease

Liver international (Print), 2016
Z. Jiang, E. Tapper, M. Connelly, C. Pimentel, L. Feldbrügge, Misung Kim, S. Krawczyk, N. Afdhal, S. Robson, M. Herman, J. Otvos, K. Mukamal, M. Lai   +12 more
semanticscholar   +1 more source

In Situ Lipoprotein‐seeking Dye for in Vivo Real‐Time Imaging of Lipid Dysregulation Diseases

Advanced Science, EarlyView.
This study develops lipoprotein‐seeking NIR‐II dyes that specifically bind circulating lipoproteins. These dyes form ultra‐stable complexes with endogenous lipoprotein, enabling real‐time, high‐contrast imaging of fatty liver and atherosclerotic plaques. Tunable binding kinetics allow customized imaging windows.
Yijing Du, Zetao Dang, Baofeng Xu, Jiajun Xu, Dan Wang, Yuewei Zhang, Shoujun Zhu   +6 more
wiley   +1 more source

Broadening the Clinical Spectrum of Very Low Density Lipoprotein Receptor Associated Dysequilibrium Syndrome. [PDF]

Mov Disord Clin Pract, 2021
Wali GM, Wali G.
europepmc   +1 more source

Serum glucose concentration and lipid profile in racing horses [PDF]

, 2011
The aim of the present work was to evaluate serum glucose concentration and lipid profile in racing horses in Iraq. Blood samples were collected from the jugular vein of 92 clinically healthy racing horses (males and females, Arabian and Cross bred), 2-8
H. A. Al-Hadithy, R. M. Hameed, S. A. Hasso   +2 more
core   +1 more source