Results 11 to 20 of about 531,046 (373)

Accuracy of low-density lipoprotein cholesterol estimation at very low levels

BMC Medicine, 2017
Background As the approach to low-density lipoprotein cholesterol (LDL-C) lowering becomes increasingly intensive, accurate assessment of LDL-C at very low levels warrants closer attention in individualized clinical efficacy and safety evaluation.
Renato Quispe, Aditya Hendrani, Mohamed B. Elshazly, Erin D. Michos, John W. McEvoy, Michael J. Blaha, Maciej Banach, Krishnaji R. Kulkarni, Peter P. Toth, Josef Coresh, Roger S. Blumenthal, Steven R. Jones, Seth S. Martin   +12 more
doaj   +2 more sources

Emerging Evidence of Pathological Roles of Very-Low-Density Lipoprotein (VLDL). [PDF]

Int J Mol Sci, 2022
Embraced with apolipoproteins (Apo) B and Apo E, triglyceride-enriched very-low-density lipoprotein (VLDL) is secreted by the liver into circulation, mainly during post-meal hours.
Huang JK, Lee HC.
europepmc   +2 more sources

Very Low-Density Lipoprotein Receptor [PDF]

Definitions, 2020
Very low-density lipoprotein receptor (873 aa, ~96 kDa) is encoded by the human VLDLR gene. This protein plays a role in the modulation of both reeling signaling and lipoprotein endocytosis.
openaire   +2 more sources

Very Low Density Lipoprotein Cholesterol Measurement [PDF]

Definitions, 2020
openaire   +2 more sources

Very-Low-Density Lipoprotein-Associated Apolipoproteins Predict Cardiovascular Events and Are Lowered by Inhibition of APOC-III. [PDF]

J Am Coll Cardiol, 2017
Pechlaner R, Tsimikas S, Yin X, Willeit P, Baig F, Santer P, Oberhollenzer F, Egger G, Witztum JL, Alexander VJ, Willeit J, Kiechl S, Mayr M.   +12 more
europepmc   +2 more sources

PPARδ is a very low-density lipoprotein sensor in macrophages

Proceedings of the National Academy of Sciences of the United States of America, 2003
Ajay Chawla, Chih‐Hao Lee, Yaacov Barak, Weimin He, John M. Rosenfeld, Debbie Liao, Jungyeob Han, Heonjoong Kang, Ronald M. Evans   +8 more
openalex   +2 more sources

Physiological Bases for the Superiority of Apolipoprotein B Over Low‐Density Lipoprotein Cholesterol and Non–High‐Density Lipoprotein Cholesterol as a Marker of Cardiovascular Risk

Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 2022
In 2019, the European Society of Cardiology/European Atherosclerosis Society stated that apolipoprotein B (apoB) was a more accurate marker of cardiovascular risk than low‐density lipoprotein cholesterol (LDL‐C) and non–high‐density lipoprotein ...
Tamara Glavinovic, G. Thanassoulis, J. de Graaf, P. Couture, R. Hegele, A. Sniderman   +5 more
semanticscholar   +1 more source

Efficacy and Safety of Further Lowering of Low-Density Lipoprotein Cholesterol in Patients Starting With Very Low Levels: A Meta-analysis

JAMA cardiology, 2018
Importance In the Cholesterol Treatment Trialists Collaboration (CTTC), in patients starting with low-density lipoprotein cholesterol (LDL-C) levels of approximately 3.4 mmol/L (131.5 mg/dL), there was a 22% reduction in major vascular events per 1-mmol ...
M. Sabatine, S. Wiviott, K. Im, S. Murphy, R. Giugliano   +4 more
semanticscholar   +1 more source

Moderate exercise increases affinity of large very low density lipoproteins for hydrolysis by lipoprotein lipase [PDF]

, 2015
Context: Postprandial triglyceride (TG) concentration is independently associated with cardiovascular disease risk. Exercise reduces postprandial TG concentrations but the mechanisms responsible are unclear.
Bedford, Dorothy K., Caslake, Muriel J., Cooney, Josephine, GHAFOURI, Khloud, Gill, Jason M.R., Wilson, John   +5 more
core   +1 more source

The effect of high-dose simvastatin on triglyceride-rich lipoprotein metabolism in patients with type 2 diabetes mellitus

Journal of Lipid Research, 2006
Statins decrease triglycerides (TGs) in addition to decreasing low density lipoprotein-cholesterol. Although the mechanism for the latter effect is well understood, it is still unclear how TG decrease is achieved with statin therapy.
William L. Isley, John M. Miles, Bruce W. Patterson, William S. Harris   +3 more
doaj   +1 more source