Results 41 to 50 of about 531,046 (373)

Characterization of apoM in normal and genetically modified mice

Journal of Lipid Research, 2004
A novel human apolipoprotein [apolipoprotein M (apoM)] was recently described and demonstrated to be a lipocalin. We have now examined apoM in wild-type mice and mice with genetically altered lipoprotein metabolism.
Kirsten Faber, Olof Axler, Björn Dahlbäck, Lars Bo Nielsen   +3 more
doaj   +1 more source

Lipoprotein lipase releases esterified oxylipins from very low-density lipoproteins [PDF]

Prostaglandins, Leukotrienes and Essential Fatty Acids, 2008
We previously demonstrated that defects in lipoprotein metabolism alter the distribution of oxygenated polyunsaturated fatty acids (PUFAs) in lipoprotein particles. If these oxidation products are released by lipoprotein lipase (LpL), then their delivery to peripheral tissues with bulk lipids could influence cellular function.
Gregory C, Shearer, John W, Newman
openaire   +2 more sources

Human lipoproteins have divergent neutralizing effects on E. coli LPS, N. meningitidis LPS, and complete Gram-negative bacteria

Journal of Lipid Research, 2004
The use of lipoproteins has been suggested as a treatment for Gram-negative sepsis because they inhibit lipopolysaccharide (LPS)-mediated cytokine production.
Tom Sprong, Mihai G. Netea, Peter van der Ley, Trees J.G. Verver-Jansen, Liesbeth E.H. Jacobs, Anton Stalenhoef, Jos W.M. van der Meer, Marcel van Deuren   +7 more
doaj   +1 more source

ApoB-48 and apoB-100 differentially influence the expression of type-III hyperlipoproteinemia in APOE*2 mice

Journal of Lipid Research, 2002
Apolipoprotein E (apoE) is essential for the clearance of plasma chylomicron and VLDL remnants. The human APOE locus is polymorphic and 5–10% of APOE*2 homozygotes exhibit type-III hyperlipoproteinemia (THL), while the remaining homozygotes have less ...
Myron E. Hinsdale, Patrick M. Sullivan, Hafid Mezdour, Nobuyo Maeda   +3 more
doaj   +1 more source

Metabolic profiling of fatty liver in young and middle-aged adults : Cross-sectional and prospective analyses of the Young Finns Study [PDF]

, 2016
Nonalcoholic fatty liver is associated with obesity-related metabolic disturbances, but little is known about the metabolic perturbations preceding fatty liver disease. We performed comprehensive metabolic profiling to assess how circulating metabolites,
Ala-Korpela, Mika, Hutri-Kähönen, Nina, Jula, Antti, Juonala, Markus, Kaikkonen, Jari E., Kangas, Antti J., Kähönen, Mika, Lehtimäki, Terho, Lehtovirta, Miia, Mikkilä, Vera, Raitakari, Olli T., Rönnemaa, Tapani, Soininen, Pasi, Suomela, Emmi, Viikari, Jorma S.A., Würtz, Peter   +15 more
core   +5 more sources

ANGPTL3 Decreases Very Low Density Lipoprotein Triglyceride Clearance by Inhibition of Lipoprotein Lipase*

Journal of Biological Chemistry, 2002
KK/San is a mutant mouse strain established in our laboratory from KK obese mice. KK/San mice show low plasma lipid levels compared with wild-type KK mice despite showing signs of hyperglycemia and hyperinsulinemia.
Tetsuya Shimizugawa, Mitsuru Ono, M. Shimamura, Kenichi Yoshida, Yosuke Ando, R. Koishi, Kenjiro Ueda, T. Inaba, Hiroyuki Minekura, T. Kohama, H. Furukawa   +10 more
semanticscholar   +1 more source

Quantitative fluorescence imaging reveals point of release for lipoproteins during LDLR-dependent uptake[S]

Journal of Lipid Research, 2013
The LDL receptor (LDLR) supports efficient uptake of both LDL and VLDL remnants by binding lipoprotein at the cell surface, internalizing lipoprotein through coated pits, and releasing lipoprotein in endocytic compartments before returning to the surface
Shanica Pompey, Zhenze Zhao, Kate Luby-Phelps, Peter Michaely   +3 more
doaj   +1 more source

A double-blind randomized trial of fish oil to lower triglycerides and improve cardiometabolic risk in adolescents. [PDF]

, 2014
OBJECTIVES: To determine the efficacy of 4 g/day fish oil to lower triglycerides and impact lipoprotein particles, inflammation, insulin resistance, coagulation, and thrombosis.
Balagopal, Prabhakaran Babu, Falkner, Bonita, Gidding, Samuel S, Hossain, Jobayer, Kwiterovich, Peter, Prospero, Carol, Zappalla, Frances   +6 more
core   +2 more sources

Interaction of rat plasma very low density lipoprotein with lipoprotein lipase-rich (postheparin) plasma.

Journal of Lipid Research, 1975
Incubation of 125I-labeled very low density lipoprotein (VLDL) with lipoprotein lipase-rich (postheparin) plasma obtained from intact or supradiaphragmatic rats resulted in the transfer of more than 80% of apoprotein C from VLDL to high density ...
S Eisenberg, D Rachmilewitz
doaj   +1 more source

DELP Treatment on Vision and Retinal Microcirculation in Patients With Acute Ischemic Stroke: Report of Five Cases and Literature Review

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background The delipid extracorporeal lipoprotein filter from plasma (DELP) treatment can effectively reduce blood lipid, increase blood flow, and improve neurological deficits in patients with acute ischemic stroke (AIS). However, its effect on vision and retinal microcirculation in stroke patients has never been reported.
Ning Li, Ronghua Hong, Hua You, Feiping Xu, Qingjun Zhang, Yiwen Lin, Yuting Su, Danmei Lan, Lingjing Jin, Junhui She   +9 more
wiley   +1 more source