Results 41 to 50 of about 921,112 (261)

Sequelae of premature birth in young adults [PDF]

, 2020
Background and Purpose Qualitative studies about the abnormalities appreciated on routine magnetic resonance imaging (MRI) sequences in prematurely born adults are lacking. This article aimed at filling this knowledge gap by (1) qualitatively describing
Bartmann, Peter, Boecker, Henning, Boeckh-Behrens, Tobias, Bäuml, Josef G., Daamen, Marcel, Hedderich, Dennis M., Menegaux, Aurore, Scheef, Lukas, Sorg, Christian, Spiro, Judith E., Wolke, Dieter, Zimmer, Claus   +11 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Epicardial pacemaker insertion in a preterm very low birth weight neonate – An anaesthetic challenge

Annals of Cardiac Anaesthesia, 2022
Congenital complete heart block (CCHB) has an incidence of one in 20,000 live births and carries a 20% risk of mortality. The hemodynamic instability due to bradycardia and asystole due to the increasing metabolic demands can be avoided by appropriate ...
Avneet Singh, Ganesh Kumar, Kulbhushan Saini, Gangadharan Prabhakaran   +3 more
doaj   +1 more source

A predictive score for retinopathy of prematurity in very low birth weight preterm infants [PDF]

, 2011
Aims This study describes the development of a score based on cumulative risk factors for the prediction of severe retinopathy of prematurity (ROP) comparing the performance of the score against the birth weight (BW) and gestational age (GA) in order to ...
A Aggarwal, A Hellstrom, A Hellstrom, A Patz, AL Hard, C Gilbert, C Lofqvist, C Lofqvist, DK Wallace, Early Treatment for Retinopathy of Prematurity Cooperative Group, EZ Martinez, G Binenbaum, G U Eckert, GE Quinn, HL Chen, J B Fortes Filho, J Chen, JB Fortes Filho, JB Fortes Filho, JB Fortes Filho, JB Fortes Filho, JB Fortes Filho, JI Hagadorn, K Allegaert, LE Smith, M Eriksson, M Maia, MS Brown, O Aydemir, P Manzoni, R S Procianoy, S Fluckiger, SE Brooks, Thomas Aaberg, VA Shah   +34 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Genetic aspects of calving, growth, and carcass traits in beef cattle [PDF]

, 2003
The aim of this thesis was to learn more about the genetic background of calving, growth and carcass traits of beef cattle breeds in Sweden, and to assess the possibility of including calving traits and commercial carcass traits in the genetic evaluation.
Eriksson, Susanne
core  

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Association between admission hypothermia and outcomes in very low birth weight infants in China: a multicentre prospective study

BMC Pediatrics, 2020
Background The objective of this prospective, multicentre, observational cohort study was to evaluate the association between admission hypothermia and neonatal outcomes in very low-birth weight (VLBW) infants in multiple neonatal intensive care units ...
Yong-hui Yu, Li Wang, Lei Huang, Li-ling Wang, Xiao-yang Huang, Xiu-fang Fan, Yan-jie Ding, Cheng-yuan Zhang, Qiang Liu, Ai-rong Sun, Yue-hua Zhao, Guo Yao, Cong Li, Xiu-xiang Liu, Jing-cai Wu, Zhen-ying Yang, Tong Chen, Xue-yun Ren, Jing Li, Mei-rong Bi, Fu-dong Peng, Min Geng, Bing-ping Qiu, Ri-ming Zhao, Shi-ping Niu, Ren-xia Zhu, Yao Chen, Yan-ling Gao, Li-ping Deng   +28 more
doaj   +1 more source

Born too early and too small: higher order cognitive function and brain at risk at ages 8–16 [PDF]

, 2019
Prematurity presents a risk for higher order cognitive functions. Some of these deficits manifest later in development, when these functions are expected to mature. However, the causes and consequences of prematurity are still unclear.
Clark, Chris A., Clayden, Jonathan D., Córcoles Parada, Marta, Giménez Mateo, Rocío, López, Leidy, Mansilla, Francisco, Martínez, Andrés, Muñoz López, Mónica, Onsurbe, Ignacio, Pérez Hernández, Elena, San Román, Paloma, Serrano del Pueblo, Víctor, Ubero Martínez, Mar   +12 more
core   +6 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source