Results 71 to 80 of about 921,112 (261)

Morbidity and Mortality ofVery Low Birth Weight Infant Graduates of a Level Three Neonatal Intensive Care Unit [PDF]

open access: yes, 2007
Purpose: To describe the morbidity and mortality of very low birth weight (VLBW) infant graduates of a level three neonatal intensive care unit (NICU) in a medically underserved population.
Cortes, Maria
core   +1 more source

Decline in the negative association between low birth weight and cognitive ability [PDF]

open access: yes, 2016
Low birth weight predicts compromised cognitive ability. We used data from the 1958 National Child Development Study (NCDS), the 1970 British Cohort Study (BCS), and the 2000–2002 Millennium Cohort Study (MCS) to analyze how this association has changed ...
Goisis, Alice   +2 more
core   +2 more sources

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

White matter volume and anisotropy in very low birth weight preterm born children: association with cognitive outcome [PDF]

open access: yes, 2006
INTRODUCTION: Low birth weight premature infants are at risk of brain injury, especially to the white matter. These complications result from either the inability to repair the lesions acquired around birth, or disruption of the normal maturation process.
Chua, SE   +7 more
core  

White matter alterations of the corticospinal tract in adults born very preterm and/or with very low birth weight [PDF]

open access: yes, 2015
White matter (WM) injury, either visible on conventional magnetic resonance images (MRI) or measurable by diffusion tensor imaging (DTI), is frequent in preterm born individuals and often affects the corticospinal tract (CST).
Bartmann, Peter   +12 more
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Growth monitoring of very low-birth weight infants

open access: yesCurrent Medicine Research and Practice, 2012
Very low-birth weight (VLBW) infants suffer significant perinatal and neonatal morbidity. The survival of VLBW infants has improved over the past few decades.
Manoj Modi
doaj  

Determinan Kematian Neonatal Dini di RSUD Dr. Achmad Mochtar Bukittinggi [PDF]

open access: yes, 2007
The Indonesia Demographic and Health Survey (SDKI) 2002-2003 reported neonatal death rate in Indonesia of 20 per 1000 live birth. Most of the neonatal death occurred early, that is in the age of infant of 0-7 days.
Efriza, E. (Efriza)
core   +4 more sources

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

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