Results 31 to 40 of about 291,310 (259)

Engineering Osteoimmune Responses with Functionalized Orthopedic Implants for Post‐Operative Osteosarcoma Treatment

Advanced Science, EarlyView.
Osteosarcoma is the most common primary bone tumor with limited treatment options and a terrible prognosis. This review provides a comprehensive summary of the recent development of osteoimmunomodulatory implants for post‐operative osteosarcoma treatment, of which the potential utility in evoking durable anti‐osteosarcoma immunity and accelerating bone
Yilong Dong, Lingshuang Wang, Hui Zhang, Menghuan Li, Zhong Luo, Yan Hu, Chunyuan Cai   +6 more
wiley   +1 more source

Renal Calcification in Very Low Birth Weight Infants

Pediatrics & Neonatology, 2011
Renal calcification in preterm infants has been described frequently. The etiologic factors have not yet been fully clarified. The objective of this study was to evaluate the incidence of and risk factors for renal calcification in our population.We retrospectively reviewed the charts of very low birth weight preterm infants during a 1-year period ...
Hung-Yang Chang, Chyong-Hsin Hsu, Jeng-Daw Tsai, Sung-Tse Li, Han-Yang Hung, Hsin-An Kao, Jui-Hsing Chang, Hsueh-Yu Chung, Hsin-Kai Wang   +8 more
openaire   +3 more sources

Running and jumping variables in RD designs: Evidence based on race, socioeconomic status, and birth weights [PDF]

, 2010
Throughout the years spanned by the US Vital Statistics Linked Birth and Infant Death Data (1983-2002), birth weights are measured most precisely for children of white and highly educated mothers.
Barreca, Alan, Guldi, Melanie, Lindo, Jason M., Waddell, Glen R.   +3 more
core  

Reducing exposure to high levels of perfluorinated compounds in drinking water improves reproductive outcomes: evidence from an intervention in Minnesota. [PDF]

, 2020
BackgroundPer- and polyfluoroalkyl substances (PFASs) have been detected in drinking water supplies around the world and are the subject of intense regulatory debate.
Auffhammer, Maximilian, Grandjean, Philippe, Rogers, Martha, Sunding, David, Waterfield, Gina   +4 more
core   +3 more sources

Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs

Advanced Science, EarlyView.
Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou, Sisi Luo, Binliang Tang, Zhiqiang Liu, Yuchuan Zhou, Yicong Meng, Zhengmu Wu, Zheng Sun, Weihui Shi, Jianzhong Sheng, Chuanjin Yu, Zhenhua Li, Siyi Wei, Mo Zhang, Yujie Luo, Jing Yan, Xueyun Qin, Jiahang Mo, Chengliang Zhou, Jinsong Li, Hefeng Huang, Yifu Ding, Guolian Ding   +22 more
wiley   +1 more source

Contributors to Dysbiosis in Very-Low-Birth-Weight Infants

Journal of Obstetric, Gynecologic, & Neonatal Nursing, 2020
The objective of this commentary was to analyze the causes and outcomes of gut microbiome dysbiosis in preterm infants who are born at very low birth weight (VLBW). The intrauterine development of VLBW infants is interrupted abruptly with preterm birth and followed by extrauterine, health-threatening conditions and sequelae.
Groer, Maureen W., Miller, Elizabeth M., D'Agata, Amy, Ho, Thao T.B., Dutra, Samia V., Yoo, Ji Youn, Yee, Alyson L., Gilbert, Jack A., Dishaw, Larry J.   +8 more
openaire   +4 more sources

Glutamine Metabolism in Very Low Birth Weight Infants [PDF]

Pediatric Research, 1997
To quantitate glutamine kinetics in premature infants and determine whether glutamine affects leucine metabolism. 11 very low birth weight (< 1250 g) neonates received 4-h i.v. infusions of L-[2H3]leucine and L-[13C5]glutamine, along with orogastric infusion of L-[I-13C]leucine and L-[I-13C]glutamine on the 10th d of life and in the fed state. Patients
D, Darmaun, J C, Roig, N, Auestad, B K, Sager, J, Neu   +4 more
openaire   +2 more sources

Household food insecurity positively associated with increased hospital charges for infants [PDF]

, 2019
Objective: To test whether household food insecurity (HFI) was associated with total annual hospitalization charges, annual days hospitalized, and charges per day, among low-income infants (months) with any non-neonatal hospital stays.
Bovell-Ammon, Allison R, Casey, Patrick H., Coleman, Sharon, Cook, John T., Cutts, Diana, Ettinger de Cuba, Stephanie, Frank, Deborah A., Heeren, Timothy C.   +7 more
core   +2 more sources

Zinc Exposure Causes Disulfidptosis to Induce Miscarriage by Up‐Regulating GATA1/METTL1/SLC7A11 Axis

Advanced Science, EarlyView.
Zn exposure up‐regulates GATA1, promoting GATA1‐mediated METTL1 and SLC7A11 transcription. It also enhances METTL1‐mediated m7G modification on SLC7A11 mRNA, increasing SLC7A11 mRNA stability. Ultimately, Zn exposure up‐regulates SLC7A11 at both transcriptional and post‐transcriptional levels, causing disulfidptosis. Knockdown of murine Slc7a11, Gata1,
Wenxin Huang, Yi Sun, Yanxin Wang, Haijun Yan, Xiaoping Yue, Weidong Wu, Xueyu Chen, Jinfang Zhang, Yanbing Lin, Qiong Lei, Nan Ji, Shuaishuai Xing, Liqin Zeng, Qingzheng Kang, Depeng Zhao, Geng Guo, Huidong Zhang   +16 more
wiley   +1 more source

Replacing iron-folic acid with multiple micronutrient supplements among pregnant women in Bangladesh and Burkina Faso: costs, impacts, and cost-effectiveness. [PDF]

, 2019
Consumption of multiple micronutrient supplements (MMS) during pregnancy offers additional benefits compared with iron-folic acid (IFA) supplementation, but the tablets are more expensive.
Engle-Stone, Reina, Kumordzie, Sika M, Meinzen-Dick, Laura, Vosti, Stephen A   +3 more
core   +1 more source