Results 61 to 70 of about 92,950 (263)

Ubiquitination of ACSL4 by Parkin Suppresses Ferroptosis and Rescues Glucocorticoid‐Induced Bone Loss

Advanced Science, EarlyView.
GCs reduce Parkin, leading to ACSL4 accumulation and PUFA‐phospholipid‐driven ferroptosis in BMSCs, which impairs osteogenesis and promotes adipogenesis, causing GIOP. Parkin restoration (via OE‐Parkin or Parkin‐LNP@DSS6) ubiquitinates and degrades ACSL4, inhibiting ferroptosis, rescuing bone formation, and rescues GIOP bone loss.
Li‐jiang Han, Jian‐sen Miao, Yi‐feng Shi, Yi‐ting Tu, Yu‐zhe Lin, Lin‐Jie Chen, Bing‐hao Lin, Hua‐lin Li, Xuan‐qi Zheng, Hong‐qiang Wu, Hai‐xiao Liu, Lei Yang, Ai‐min Wu, Zhen Lin, Jian Xiao, Gang Zheng, Chen Jin   +16 more
wiley   +1 more source

Nephrocalcinosis in very low birth weight infants.

Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia, 2010
To determine the incidence and risk factors of nephrocalcinosis in preterm infants, we studied in a prospectively 64 preterm infants of birth weight :5 1500 g from February 2006 to November 2007. Data were collected on gestation, birth weight, gender and family history of renal calculi, respiratory support, and use of nephrotoxic drugs.
Nasseri Fatemeh, Azhir Afshin, Rahmanian Shiva, Iranpour Ramin, Adibi Atoosa   +4 more
openaire   +2 more sources

Contributors to Dysbiosis in Very-Low-Birth-Weight Infants

Journal of Obstetric, Gynecologic, & Neonatal Nursing, 2020
The objective of this commentary was to analyze the causes and outcomes of gut microbiome dysbiosis in preterm infants who are born at very low birth weight (VLBW). The intrauterine development of VLBW infants is interrupted abruptly with preterm birth and followed by extrauterine, health-threatening conditions and sequelae.
Groer, Maureen W., Miller, Elizabeth M., D'Agata, Amy, Ho, Thao T.B., Dutra, Samia V., Yoo, Ji Youn, Yee, Alyson L., Gilbert, Jack A., Dishaw, Larry J.   +8 more
openaire   +4 more sources

Soft, Multi‐Wavelength Photoplethysmography Enables Reliable Neonatal Blood Pressure Monitoring Via Error Stratification

Advanced Science, EarlyView.
A soft hybrid multi‐wavelength PPG wearable acquires neonatal signals. Synchronized PPG and invasive ABP data are segmented into fixed windows. A 1D‐EfficientNet model predicts segment‐level SBP and DBP. Model performance is examined with retrospective subgroup analysis across acquisition conditions.
Wenqi Shi, Lanlan Mi, Jiarong Chen, Biao Liu, Min Wang, Zisheng Dai, Bin Liu, Ruize Gao, Yunfeng Lin, Weiwei Guo, Guoxing Wang, Wenyi Luo, Cheng Chen   +12 more
wiley   +1 more source

Correlation between the duration of early antibiotic exposure and clinical outcomes in high-risk preterm infants

徐州医科大学学报
Objective To investigate the association between the duration of early antibiotic exposure and early outcomes in high-risk preterm infants.Methods Retrospective analysis was conducted on neonates with gestational age 7 days.
ZHOU Jiming, LIU Wenqiang, YANG Qianqian, YE Lili, XU Yan   +4 more
doaj   +1 more source

Recomendaciones para la creación y el funcionamiento de los bancos de leche materna en España

Anales de Pediatría, 2018
Resumen: La mejor alimentación para un recién nacido es la leche de su propia madre. En aquellos casos en los que esta no está disponible, especialmente en los recién nacidos muy prematuros o de muy bajo peso al nacer, así como en otros recién nacidos ...
Javier Calvo, Nadia Raquel García Lara, María Gormaz, Manuela Peña, María José Martínez Lorenzo, Pilar Ortiz Murillo, Josep Maria Brull Sabaté, Carmen María Samaniego, Antoni Gayà   +8 more
doaj   +1 more source

Prevention of human milk-acquired cytomegalovirus infection in very-low-birth-weight infants

BMC Pediatrics, 2023
Background The aim of the study was to determine the rate of cytomegalovirus virolactia in the human milk (HM) of mothers of VLBW infants, compare the CMV infection rates and the changes in CMV DNA viral load and nutrient profile among different HM ...
Mi Lim Chung, Heungsup Sung, Euiseok Jung, Byong Sop Lee, Ki Soo Kim, Ellen Ai-Rhan Kim   +5 more
doaj   +1 more source

m6A‐Driven Pexophagy Triggers Placental Ferroptosis to Impair Fetal Growth Upon Environmental Stress

Advanced Science, EarlyView.
Prenatal environmental stress exposure promotes m6A modification to drive PEX2‐dependent pexophagy, thereby causing placental ferroptosis and FGR. ABSTRACT The role and underlying mechanisms of placental ferroptosis in fetal growth restriction (FGR) induced by environmental stress remain poorly understood.
Xin‐Xin Zhang, Ye‐Xin Luo, Cheng‐Fang Sun, Rui Pan, Yu‐Xi Wu, Zhi Yuan, Xin‐Run Wang, Xu‐Dong Zhang, Lan‐Lan Wu, Xiang‐Yu Yao, Zhan‐Dong Song, Wei Chang, Tian Wei, Pan‐Yuan Cai, Tian‐Ci Zhang, Yong‐Wei Xiong, De‐Xiang Xu, Hua Wang, Hua‐Long Zhu   +18 more
wiley   +1 more source

Factors associated with weight Z-score in very low birth weight and extremely low birth weight preterm infants during hospitalization

Jornal de Pediatria
Objective: To investigate the behavior of weight-for-age z-score (WAZ) and associated factors in preterm newborns (PTNB) with very low birth weight (VLBW) and extremely low birth weight (ELBW), comparing them to low birth weight (LBW) during four weeks ...
Eduarda Couto Plácido Nunes, Eduarda Silva, Eduarda Dallmann Lopes Pereira, Karla Pereira Machado, Sandra Costa Valle   +4 more
doaj   +1 more source

Livestock Multi‐Omics Integration: A Systematic Framework From Statistical Association to Causal Interpretation

Advanced Science, EarlyView.
A three‐tier livestock multi‐omics framework resolves four typical analytical pitfalls. Moving from statistical association through machine learning preprocessing to triple‐modal causal inference, it converts omics results into genomic selection and gene editing strategies to achieve One Health, underpinned by multi‐omics data, multimodal sequencing ...
Jiying Wen, Zhongyu Wang, Jieping Huang, Fen Li, Ningbo Chen, Yun Ma   +5 more
wiley   +1 more source