Results 41 to 50 of about 16,207,375 (298)

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Autism and mild epilepsy associated with a de novo missense pathogenic variant in the GTPase effector domain of DNM1

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView., 2023
Abstract Dynamin 1 is a GTPase protein involved in synaptic vesicle fission, which facilitates the exocytosis of neurotransmitters necessary for normal signaling. Pathogenic variants in the DNM1 gene are associated with intractable epilepsy, often manifested as infantile spasms at onset, developmental delay, and a movement disorder, and are located in ...
Davide Mei, Elena Parrini, Claudia Bianchini, Maria Luisa Ricci, Renzo Guerrini   +4 more
wiley   +1 more source

Quality improvement bundles to decrease hypothermia in very low/extremely low birth weight infants at birth: a systematic review and meta-analysis [PDF]

PeerJ
Background Numerous studies have demonstrated that hypothermia in preterm infants correlates with increased morbidity and mortality, especially among those with very low or extremely low birth weights (VLBW/ELBW).
Guichao Zhong, Jie Qi, Lijuan Sheng, Jing Zhuang, Zhangbin Yu, Benqing Wu   +5 more
doaj   +2 more sources

OPHTHALMOLOGIC FINDINGS IN VERY LOW BIRTH WEIGHT INFANTS

Journal of Pediatric Ophthalmology & Strabismus, 1998
J Pediatr Ophthalmol ...
Asproudis, I., Andronikou, S., Griva, E., Psilas, K.   +3 more
openaire   +3 more sources

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Low and Very Low Birth Weight in Infants Conceived With Use of Assisted Reproductive Technology

, 2002
BACKGROUND: The increased risk of low birth weight associated with the use of assisted reproductive technology has been attributed largely to the higher rate of multiple gestations associated with such technology.
Meikle, Susan F., Ferre, Cynthia, Schieve, Laura A., Peterson, Herbert B., Wilcox, Lynne S., Jeng, Gary   +5 more
core   +1 more source

Do ethnic differences in cord blood leptin levels differ by birthweight category? Findings from the Born in Bradford cohort study. [PDF]

, 2014
BACKGROUND: There is evidence that South Asian individuals have higher fat mass for a given weight than Europeans. One study reported that the greater fatness for a given birthweight may increase with increasing birth weight, suggesting that any attempt ...
Wright, John, West, J, Wright, J., Lawlor, D., Sattar, N, Fairley, Lesley, Sattar, Naveed, Whincup, Petter, Sattar, N., Whincup, P., Fairley, L, Whincup, P, Lawlor, Debbie A., Lawlor, DA, West, J., Wright, J, West, Jane, Fairley, L.   +17 more
core   +1 more source

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito, Kamal Benguerba, Ken Tsuchida, Kazushige Yazawa, Isao Tsumiyama, Hiromitsu Kayama, Sandra P. Reyna, Farid Khan, Richard S. Finkel   +8 more
wiley   +1 more source

Survival of very low birth weight children and contributing factors: A study from Tehran, Iran

Payesh, 2021
Objectives: Birth of an infant with very low birth weight (VLBW) (weight less than 1500 grams) is a major cause of deaths and complications in infancy and childhood.
Ramin Mozafari kermani, Jila Sadighi, Abbas Habibollahi, Mahmoud Tavousi, Ali Asghar Haeri Mehrizi, Raheleh Rostami   +5 more
doaj  

Fluid and Electrolyte Management of Very Low Birth Weight Infants

Pediatrics and Neonatology, 2012
Recent advances in medical knowledge and technology have markedly improved the survival rates of very low birth weight infants. Optimizing the neuro-developmental outcomes of these survivors has become an important priority in neonatal care, which ...
William Oh
doaj   +1 more source