Results 51 to 60 of about 209,249 (279)

Correlation of Matrix Metalloproteinases and Tissue Inhibitors of Matrix Metalloproteinase Expression in Ileal Carcinoids, Lymph Nodes and Liver Metastasis with Prognosis and Survival [PDF]

, 2009
Purpose: Ileal carcinoids are gut epithelial tumors originating from serotonin-containing enterochromaffin (EC) cells. Therapeutic options for effectively inhibiting the growth and spread of metastatic carcinoids are still limited.
Baur, Dorothee M., Besig, Sophie, Braun, Thomas, Hoefler, Heinz, Langer, Rupert, Perren, Aurel, Prinz, Christian, Rad, Roland, Voland, Petra   +8 more
core   +2 more sources

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Vesicular Diseases in Livestock with Special Reference to Foot and Mouth Disease

Journal of Pure and Applied Microbiology, 2017
Many vesicular diseases are caused by viruses due to their epitheliotropic nature, which are characterized by formation of vesicles. Vesicles are found on oral mucosa, on the feet, and on the mammary glands of females.
Rakesh Kumar, Venketaramireddy Balena, Shailesh Kumar Patel   +2 more
doaj   +1 more source

Characterization of Vesicular Monoamine Transporter 2 and its role in Parkinson\u27s Disease Pathogenesis using Drosophila [PDF]

, 2016
Parkinson’s disease (PD) is a progressive neurodegenerative disorder caused by the selective loss of the dopaminergic neurons in the Substantia nigra pars compacta region of the brain.
Tito, Antonio Joel, Jr., Zhang, Sheng
core   +1 more source

Construction of a Plasmodium falciparum Rab-interactome identifies CK1 and PKA as Rab-effector kinases in malaria parasites [PDF]

, 2011
Background information The pathology causing stages of the human malaria parasite Plasmodium falciparum reside within red blood cells that are devoid of any regulated transport system.
Bourdoncle, P., Chandran, S., Dandavate, V., Langsley, G., Meissner, M., Ndjembo-Ezougou, C., Rached, F.B., Talabani, H., Tatu, U., Yera, H.   +9 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Agronomic Management of Indigenous Mycorrhizas [PDF]

, 2008
Many of the advantages conferred to plants by arbuscular mycorrhiza (AM) are associated to the ability of AM plants to explore a greater volume of soil through the extraradical mycelium.
A Gollotte, A Heggo, A Hodge, A Liu, A Manjunath, A Mollier, A Mozafar, AD Rovira, AE Richardson, AI Sannazzaro, AS El-Hassanin, B Frey, BAD Hetrick, BL Allen, C Azcón-Aguilar, C Cordier, C Grant, C Kessel van, C Plenchette, C Plenchette, C Val Del, CL Boddington, CL Boddington, CM Hepper, CM Hepper, CP Chandrashekara, D Redecker, D Tuinen van, DD Douds Jr, DD Douds Jr, DD Douds Jr, DG Evans, DG Evans, DJ Read, DP Stribley, E George, E Sieverding, EA Drew, EJ Joner, EJ Joner, EJ Joner, F Borie, F Feldmann, F Oehl, F Oehl, F Rivera-Becerril, FE Sanders, FRS Ahmed, G Becard, GJ Bethlenfalvay, GL Fairchild, GL Fairchild, GN Al-Karaki, H Hauggaard-Nielsen, H Kahiluoto, H Kahiluoto, H Kahiluoto, HA Alten von, HD Addy, I Brito, I Brito, I Jakobsen, I Ortas, ICR Holford, J Arihara, J Arines, J B Morton, J Jansa, J Jansa, J Jansa, J Scullion, JA Menge, JA Menge, JB Morton, JC Dodd, JC Dodd, JCC Miranda, JD Driver, JH Graham, JH Graham, JM Tisdall, JM Tisdall, JN Klironomos, K Cho, K Jayachandran, K Tawaraya, K Turnau, K Yano, KA Moyer-Henry, KM Harinikumar, L Corkidi, L Galvez, L Munkvold, L Simon, LK Abbott, LK Abbott, LK Abbott, M Bucher, M Franke-Snyder, M Gollner, M Gryndler, M Habte, M Niemi, M Saito, M Vestberg, M Vivekanandan, M Yamato, MA Martins, MA Nogueira, MA Nogueira, MC Rillig, MC Rillig, ME Gavito, ME Gavito, MH Miller, MH Miller, MH Ryan, MJ Goss, MJ Goss, MM Hart, MW Schwartz, N Mathimaran, NC Johnson, NC Johnson, NC Johnson, NP Wellings, NR Jordan, NS Bolan, P Audet, P Gosling, P Vandenkoornhuyse, PD Steinberg, PM Antunes, PM Antunes, PM Antunes, PM Chalk, R Azcón, R Duponnois, R Kjøller, R Lal, R Pandey, R Toth, RB Clark, RB Clark, RJ Cook, RLB Black, RM Augé, RM Miller, RP Schreiner, RP Schreiner, RPS Kesava, RS Oliveira, RS Thomas, RT Koide, RT Koide, S Dickson, S Gianinazzi, S Lu, S Mohandas, S Subhan, SC Vyas, SE Smith, SF Salem, SF Wright, SF Wright, SH Burleigh, SK Kothari, T Karasawa, T Karasawa, T Karasawa, TP McGonigle, TP McGonigle, TP McGonigle, TP McGonigle, TP McGonigle, TP McGonigle, TR Cavagnaro, V Gupta, V Göhre, W Hendrix, X He, XL Li, YG Zhu, Z Kabir, Z Kabir, Z Kabir, Z Kabir, Z Kabir, Z Kabir, Z Kabir, ZI Troeh   +190 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gabor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Viroses confundíveis com febre aftosa Viral diseases to be differentiated from foot-and-mouth disease

Ciência Rural, 1996
Revisam-se as doenças que devem ser consideradas no diagnóstico diferencial de febre aftosa. Dentre as doenças vesiculares ou erosivas, descrevem-se os principais aspectos relacionados ao diagnóstico da estomatite vesicular, diarréia viral bovina, febre ...
Franklin Riet-Correa, Valéria Moojen, Paulo Michel Roehe, Rudi Weiblen   +3 more
doaj   +1 more source