Results 11 to 20 of about 977 (160)

Establishment and Application of a Novel Protein Microarray for Serological Detection and Differentiation of Senecavirus A. [PDF]

Transbound Emerg Dis
Senecavirus A (SVA) is an emerging swine pathogen that causes vesicular disease, which presents clinically indistinguishable signs from other vesicular diseases. To enable differentiation of infected from vaccinated animals (DIVA), we developed a novel protein microarray for dual serological detection of antibodies against SVA structural (VP2‐VP3‐VP1 ...
Li D, Deng J, Wang Z, Zhang Y, Li Y, Hao L, Tian K, Li X.   +7 more
europepmc   +2 more sources

Phorbol Myristate Acetate Inhibits Senecavirus A Replication by Activating IKBKE-Mediated IFN Pathway and NF-κB Signal. [PDF]

Transbound Emerg Dis
Senecavirus A (SVA) is an emerging picornavirus causing vesicular disease indistinguishable from foot‐and‐mouth disease virus (FMDV). So far, there are no commercial vaccines and effective therapeutic drugs against SVA infection in China. Here, a library of 112 compounds were screened, and we found that phorbol myristate acetate plays an antagonistic ...
Yan J, Gao Y, Guo C, Dong Y, Jiang P, Bai J.   +5 more
europepmc   +2 more sources

A Novel In-Cell ELISA With Superior Sensitivity and Specificity for the Detection of African Swine Fever Virus-Specific IgM and IgG Antibodies. [PDF]

Transbound Emerg Dis
African swine fever (ASF), a high‐profile transboundary animal disease caused by ASF virus (ASFV), imposes a devastating impact on the global swine industry. Given that vaccines are still under development, including field evaluations, early detection of ASFV is crucial for effective disease control and mitigation.
Wu P, McDaniel AJ, Rodríguez YY, O'Donnell V, Jia W.   +4 more
europepmc   +2 more sources

An evaluation of the efficiency and effectiveness of diagnostic tests for foot and mouth disease: are novel diagnostic tests for FMD more feasible than conventional tests in Southeast Asia? [PDF]

Aust Vet J
Foot and mouth disease (FMD) remains endemic in many areas of continental Southeast Asia (SEA). It is responsible for substantial economic losses in the smallholder sector and threatens livelihoods. In recent years, novel diagnostic tests have been developed which reportedly detect FMD virus more effectively and efficiently.
Tan WY, Ward MP.
europepmc   +2 more sources

Epitope Mapping of <i>Senecavirus A</i> 3A Protein Using Monoclonal Antibodies. [PDF]

Transbound Emerg Dis
Senecavirus A (SVA), an emerging pathogen causing vesicular disease in pigs, poses a significant threat to the swine industry. The nonstructural protein 3A of SVA plays an essential role in the viral replication cycle. In this study, we immunized mice with the prepared SVA 3A protein and produced two monoclonal antibodies (mAbs), AG4 and 2F3.
Meng L, Tian XX, Xiang XY, Qi XY, Zhou HR, Xiao PY, An TQ, Meng FD, Wang HW.   +8 more
europepmc   +2 more sources

Covid-19 dermatoses: Acral vesicular pattern evolving into bullous pemphigoid. [PDF]

Skin Health Dis, 2021
Abstract Bullous pemphigoid (BP) appears to be rising in incidence across the Western World, especially in the elderly. Some of the pathogenetic mechanisms involving antigen mimicry and antibody cross‐reactivity have been elucidated for cases associated with neurological disease and certain drugs.
Goon PKC, Bello O, Adamczyk LA, Chan JYH, Sudhoff H, Banfield CC.   +5 more
europepmc   +2 more sources

Expert opinion on the identification, risk assessment, and mitigation of microorganisms and parasites relevant to xenotransplantation products from pigs

Xenotransplantation, Volume 30, Issue 5, September/October 2023., 2023
Abstract Xenotransplantation has the potential to address shortages of organs available for clinical transplantation, but concerns exist regarding potential risks posed by porcine microorganisms and parasites (MP) to the health of human recipients. In this study, a risk‐based framework was developed, and expert opinion was elicited to evaluate porcine ...
Huybert Groenendaal, Solenne Costard, Reid Ballard, Stephen Bienhoff, Diana C. Challen, Brandon J. Dominguez, Douglas R. Kern, Dan Miller, Jeske Noordergraaf, Larisa Rudenko, Henk‐Jan Schuurman, Tom Spizzo, Matthew Sturos, Bill Zollers, Jay A. Fishman   +14 more
wiley   +1 more source

Development and evaluation of a real-time RT-PCR and a field-deployable RT-insulated isothermal PCR for the detection of Seneca Valley virus

BMC Veterinary Research, 2019
Background Seneca Valley virus (SVV) has emerged in multiple countries in recent years. SVV infection can cause vesicular lesions clinically indistinguishable from those caused by other vesicular disease viruses, such as foot-and-mouth disease virus ...
Jianqiang Zhang, Charles Nfon, Chuan-Fu Tsai, Chien-Hsien Lee, Lindsay Fredericks, Qi Chen, Avanti Sinha, Sarah Bade, Karen Harmon, Pablo Piñeyro, Phillip Gauger, Yun-Long Tsai, Hwa-Tang Thomas Wang, Pei-Yu Alison Lee   +13 more
doaj   +1 more source

Vesivirus 2117 capsids more closely resemble sapovirus and lagovirus particles than other known vesivirus structures [PDF]

, 2017
Vesivirus 2117 is an adventitious agent that in 2009, was identified as a contaminant of CHO cells propagated in bioreactors at a pharmaceutical manufacturing plant belonging to Genzyme.
Bhella, David, Carneiro, Daniel G., Conley, Michaela, Emmott, Edward, Goodfellow, Ian G., Hansman, Grant S., Murata, Kazuyoshi, Orton, Richard, Taylor, David   +8 more
core   +1 more source

USE OF REAL-TIME qRT-PCR FOR FMD VIRUS DETECTION IN CATTLE MILK

Ветеринария сегодня, 2019
FMDV can be shed with milk of infected animals and infect susceptible animals. The possibility of using real-time qRT-PCR for FMD virus detection in cattle milk was assessed. To prepare samples of FMDV infected milk the following strains were used: А No.
A. M. Timina, S. N. Fomina, Т. К. Mayorova   +2 more
doaj   +1 more source