A review on toxic epidermal necrolysis-like superficial wound lesions: Issue and challenge on 10 clinical entities. [PDF]
Abstract Toxic epidermal necrolysis (TEN) is a severe skin reaction caused by extensive epidermal and mucosal necrosis. This clinical phenomenon is known as an acute syndrome of apoptotic pan‐epidermolysis (ASAP). The ASAP phenomenon is observed in conditions that mimic TEN, highlighting the challenge in distinguishing these conditions.
Abtahi-Naeini B +3 more
europepmc +2 more sources
Skin manifestations associated with checkpoint inhibitors
Abstract Immune checkpoint inhibitors (ICIs) are a relatively novel class of drugs whose administration has been approved for several malignancies. Adverse events are quite common, and the skin is the most frequently involved organ. In fact, regardless of the neoplasm being treated, more than 50% of patients receiving ICIs develop cutaneous immune ...
Gianluca Nazzaro +4 more
wiley +1 more source
Linear IgA/IgG bullous dermatosis successfully treated with omalizumab: A case report
Treatment of bullous diseases such as LAGBD can be difficult due to lack of treatment response. Omalizumab is a biologic drug that has not been previously reported effective in the treatment of LAGBD. Omalizumab could be a future treatment for LAGBD. Abstract Linear IgA/IgG bullous dermatosis (LAGBD) is a rare, autoimmune blistering skin disease.
Morten Bahrt Haulrig +3 more
wiley +1 more source
Pemphigus herpetiformis in a 4‐year‐old child: Case report and review of the literature
Pemphigus of childhood is rare. Pruritic herpetiform blisters with or without erythematous lesions should prompt consideration of diagnosis of pemphigus herpetiformis in this age group. Prognosis is generally good with appropriate therapy. Abstract Pemphigus herpetiformis (PH) is a rare form of pemphigus, especially when occurring in childhood ...
Faten Hayder +8 more
wiley +1 more source
Drug eruptions with novel targeted therapies – immune checkpoint and EGFR inhibitors
Summary Given the increasing use of novel targeted therapies, dermatologists are constantly confronted with novel cutaneous side effects of these agents. A rapid diagnosis and appropriate management of these side effects are crucial to prevent impairment of the patients’ quality of life and interruptions of essential cancer treatments.
Isabella Pospischil +1 more
wiley +1 more source
Figurate erythemas – update and diagnostic approach
Summary Figurate erythemas (FE) represent an etiopathophysiologically heterogeneous group of diseases defined by their characteristic annular erythematous skin lesions. Diagnosis is made primarily by clinical examination together with histological findings; often it is a diagnosis made by exclusion.
Alexander Boehner +3 more
wiley +1 more source
Unusual Oral Presentations of Herpes Simplex Virus-1: A Series of Eight Cases and Literature Review. [PDF]
ABSTRACT Aims The aim of this study is to characterize the clinical and microscopic features of recurrent oral/labial HSV‐1 infection with unusual clinical presentations. Methods A literature review and retrospective case series of patients with recurrent oral/labial HSV‐1 with unusual presentations were conducted.
de Paiva JPG +12 more
europepmc +2 more sources
Immunotherapy‐Related Cutaneous Toxicities in Melanoma: A Dermoscopic Perspective
Dermoscopy serves as a valuable tool in the everyday dermatological and oncological practice for melanoma patients, allowing for the prompt identification of immune‐related cutaneous toxicities and guiding clinicians toward appropriate therapeutic decisions.
Grażyna Kamińska‐Winciorek +3 more
wiley +1 more source
An Atypical Presentation of Lichen Planus‐Like Reaction from Pembrolizumab
Introduction. With the advent of immunotherapy, a new subtype of side effects called IRAEs or immune related adverse effects have become more common. They may present in various organ systems as colitis, pneumonitis, hypophysitis, and thyroiditis and commonly as dermatological reactions. Case.
Matthew Lee +2 more
wiley +1 more source
Drug Hypersensitivity: A Correlation Study From Histopathology to Clinic
ABSTRACT Background Drug hypersensitivity (DH) can present with varied clinical and pathological manifestations that may mislead the referring physician. Available data regarding the concordance between pathological diagnosis and clinical findings in DH are scarce.
Olivier Philip +5 more
wiley +1 more source

