Results 41 to 50 of about 2,460 (171)

GATA4‐Driven Transcription of HtrA1 Promotes Cellular Senescence in Ménière's Disease and Age‐Related Audio‐Vestibular Dysfunction

Advanced Science, Volume 13, Issue 39, 13 July 2026.
This study identifies the HDAC6/GATA4/HtrA1 axis as a critical driver of cellular senescence in the inner ear. GATA4 nuclear translocation, facilitated by HDAC6 downregulation, transcriptionally activates HtrA1, promoting hair cell senescence, SASP, and audio‐vestibular dysfunction in models of Ménière's disease and age‐related audio‐vestibular ...
Na Zhang, Na Li, Yan Wang, Jing Zhang, Jiahui Liu, Lei Chen, Yongdong Song, Yurong Mu, Yuechen Han, Yafeng Lyu, Xiaofei Li, Hanyue Wang, Jing Wang, Yao Lu, Zhaomin Fan, Daogong Zhang, Haibo Wang   +16 more
wiley   +1 more source

Cervical and ocular vestibular-evoked myogenic potentials test results and its relation to vestibular signs and symptoms in individuals with vestibular migraine

The Egyptian Journal of Otolaryngology
Objective The objective of the present study was to characterize the response rate, latency, and amplitude parameters of the cervical and ocular vestibular evoked myogenic potentials in individuals with vestibular migraine.
Adithya Sreedharan Sanitha, Sujeet Kumar Sinha   +1 more
doaj   +1 more source

Galvanic vestibular stimulation reveals disruption of ipsilesional brainstem pathways in hemiparetic stroke survivors

Experimental Physiology, Volume 111, Issue 7, Page 3381-3397, 1 July 2026.
Abstract The spatiotemporal structure of muscle coordination emerges from the collaboration and competition among cortical, brainstem and spinal pathways onto motor neuron pools, each continuously shaped by task demands, limb position and descending tract integrity.
Angelo Bartsch‐Jiménez, Hesam Azadjou, Francisco J. Valero‐Cuevas   +2 more
wiley   +1 more source

Sono‐Mechanogenetics: Linking Ultrasound Physics With Cellular Mechanobiology

Advanced Science, Volume 13, Issue 33, 15 June 2026.
Sono‐mechanogenetics links ultrasound physics with cellular mechanotransduction to enable noninvasive control of engineered biological systems. Acoustic forces generate distinct deformation modes that activate intracellular signaling pathways, which can be coupled to synthetic gene circuits to regulate diverse cellular functions, including gene ...
Yunjia Qu, Fan Wei, Chi Woo Yoon, Qifa Zhou, Yingxiao Wang   +4 more
wiley   +1 more source

Vestibular-Evoked Myogenic Potentials in Bilateral Vestibulopathy

Frontiers in Neurology, 2018
Bilateral vestibulopathy (BVP) is a chronic condition in which patients have a reduction or absence of vestibular function in both ears. BVP is characterized by bilateral reduction of horizontal canal responses; however, there is increasing evidence that
Sally M. Rosengren, Sally M. Rosengren, Miriam S. Welgampola, Miriam S. Welgampola, Rachael L. Taylor, Rachael L. Taylor   +5 more
doaj   +1 more source

Vestibular evoked myogenic potentials in the prognosis of sudden hearing loss ‒ a systematic review

Brazilian Journal of Otorhinolaryngology, 2020
Introduction: Sudden hearing loss is an otorhinolaryngological emergency that often leads to severe damage to the auditory and vestibular function. The vestibular evoked myogenic potential is a test that allows a noninvasive evaluation of the otolithic ...
Nathalia de Paula Doyle Maia, Karen de Carvalho Lopes, Fernando Freitas Ganança   +2 more
doaj   +1 more source

Extended Reality in Rehabilitation Medicine: A Systematic Review

Health Science Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background and Aims This systematic review synthesizes current evidence on the application of extended reality (XR) technologies, comprising virtual reality (VR), augmented reality (AR), and mixed reality (MR), in rehabilitation medicine, assessing their effects across diverse rehabilitation domains and clinical outcomes.
Jie Hao, Yao Yao, Ka‐Chun Siu
wiley   +1 more source

Diagnosis and Metabolic Management of Adult Refsum Disease: Guidance From the Medical and Scientific Committee of Global DARE (Defeat Adult Refsum Everywhere)

Journal of Inherited Metabolic Disease, Volume 49, Issue 3, May 2026.
ABSTRACT Adult Refsum disease (ARD; OMIM 266510) is a degenerative autosomal recessive condition typically diagnosed in adulthood. It affects visual, auditory and nervous system function. It is characterised by plasma, neuro‐ophthalmological and adipose tissue accumulation of the dietary‐derived phytanic acid (PA).
Radha Ramachandran, Raphael Buttigieg, Florian Eichler, Bart P. Leroy, Omar Mahroo, Rachel M. Huckfeldt, Sarah Firman, Eleanor Baldwin, Kristie DeMarco, Susan Kuranoff, Amena Fine, Reinhard Klingel, Sacha Ferdinandusse, Joseph G. Hacia, Ronald J. Wanders, Anthony S. Wierzbicki   +15 more
wiley   +1 more source

Vestibular evoked myogenic potentials in patients with BPPV [PDF]

Medical Science Monitor, 2011
The probable cause of Benign Paroxysmal Positional Vertigo (BPPV) is a degeneration of the oto lithic organs (utricle and saccule). The aim of the study is to find possible alterations in Vestibular Evoked Myogenic Potentials (VEMP) recordings in BPPV patients, because the saccule is part of the VEMP pathway.27 BPPV patients (24 unilateral and 3 ...
Korres, S., Gkoritsa, E., Giannakakou-Razelou, D., Yiotakis, I., Riga, M., Nikolpoulos, T.P.   +5 more
openaire   +3 more sources

Comparative Prognostic Analysis of Sudden Sensorineural Hearing Loss With Vertigo in Pediatric and Adult Patients

Laryngoscope Investigative Otolaryngology, Volume 11, Issue 2, April 2026.
ABSTRACT Objective To compare the association of vertigo with rates of frequency‐specific hearing recovery in pediatric and adult patients with unilateral idiopathic sudden sensorineural hearing loss (SSNHL). Methods A total of 80 pediatric and 444 adult patients hospitalized with SSNHL were included in this study.
Changshuo Shan, Guohui Chen, Jin Li, Feifei Guo, Yun Gao, Jiao Zhang, Jing Guan, Dayong Wang, Qiuju Wang   +8 more
wiley   +1 more source