Results 51 to 60 of about 144,693 (260)

Root‐Inspired Microneedle Patch With Interlocked Rigid‐Soft Architecture for High Tissue‐Adaptiveness

Advanced Science, EarlyView.
A root‐inspired microneedle array patch uses lattice‐based mechanical interlocking to unite rigid microneedles with a flexible substrate. The interlocked rigid–soft architecture improves interfacial bonding, supports stable adhesion on curved and wet tissues under dynamic motion, and provides a versatile platform for robust biointerfacing and future ...
Jongchan Lee, Yeongjun Song, Yonghyun Cho, Hyo In Kim, Dong‐Hyun Youn, Jinbong Park, Seungbeom Choi, Dohyun Kwon, Brian Jun Lee, Sangyul Baik   +9 more
wiley   +1 more source

TECTB Variants Reveal Tectorial Membrane Vulnerability in Dominant Non‐Syndromic Hearing Loss

Advanced Science, EarlyView.
TECTB is a non‐collagenous protein of the tectorial membrane – an extracellular matrix of the cochlea. This study identifies dominant missense variants in TECTB linked to human hereditary deafness in two unrelated families. Genetically engineered mice homozygous for one of the variants are profoundly deaf, whereas heterozygous mice have normal hearing ...
Evan B. Hale, Barbara Vona, Richard J. Goodyear, Richard T. Osgood, Jun Shen, Sami S. Amr, Karen Mojica, Michaela A. H. Hofrichter, Jörg Schröder, Sophie Flandin, Paul Gratias, Ricardo Vera‐Monroy, Katherine Callahan, Kerry L. Gudlewski, Rolen Quadros, Masato Ohtsuka, JoAnn McGee, Edward J. Walsh, Cynthia C. Morton, Thomas Haaf, Channabasavaiah Gurumurthy, James E. Saunders, Guy P. Richardson, Artur A. Indzhykulian   +23 more
wiley   +1 more source

Quality of life of individuals submitted to vestibular rehabilitation Qualidade de vida de indivíduos submetidos à reabilitação vestibular [PDF]

, 2009
Balance disorders affect social, family and professional activities. Vestibular rehabilitation can reduce the impact of these disorders on the quality of life of individuals with vertigo.
Ganança, Fernando Freitas [UNIFESP], Ganança,Cristina Freitas, Cristina Freitas Ganança, Ganança,Fernando Freitas, Ganança, Cristina Freitas [UNIFESP], Fernando Freitas Ganança, Patatas,Olívia Helena Gomes, Olívia Helena Gomes Patatas, Patatas, Olívia Helena Gomes [UNIFESP]   +8 more
core   +1 more source

Transient Sleep Deprivation Induces Persistent Auditory Neuropathy via ROS‐Initiated Neuroinflammation and BK Channel Suppression

Advanced Science, EarlyView.
Sleep disturbance severity closely tracks hearing loss in a clinical cohort, yet the mechanistic link remains unclear. Acute sleep deprivation is shown to trigger transient cochlear oxidative stress that switches into a self‐sustaining neuroinflammatory state, suppressing BK channels and causing irreversible synaptopathy.
Dan Chen, Ying Ma, Lixuan Huang, Xin Chen, Fanliang Kong, Zhenzhou Qian, Mingyue Guan, Xinlin Wang, Yanyan Yang, Shasha Zhang, Peng Li, Renjie Chai   +11 more
wiley   +1 more source

Complementary Role of Vestibular to Neurological Evaluation in Assessment of Dizzy Children [PDF]

Zagazig University Medical Journal
Background: Vestibular disorders are common among children, but often undiagnosed due to lack of vestibular assessment. Diagnosis achieved through assessment of vestibular and neurological functions.Objectives: The present work aims to evaluate ...
Youstina Attia, Ahmed Khater, Wafaa Hassan, Nahla Gad   +3 more
doaj   +1 more source

Abnormal Visuo-vestibular Interactions in Vestibular Migraine: a Cross Sectional Study [PDF]

, 2018
Vestibular migraine is amongst the commonest causes of episodic vertigo. Chronically, patients with vestibular migraine develop abnormal responsiveness to both vestibular and visual stimuli characterised by heightened self-motion sensitivity and visually-
Bednarczuk, N.F., NF Bednarczuk (7782362), de Melo, Fabiano, Kaski, D., H Rust (7789439), Arshad, Q., Bronstein, Adolfo, Chan, John, Q Arshad (7718309), Rust, H., A-S Fluri (7782368), Chan, J., AM Bronstein (7729337), Fluri, Anne-Sophie, J Chan (7789436), M Sharif (7789445), Golding, J.F., Kaski, Diego, D Kaski (7718294), Casanovas Ortega, Marta, Seemungal, B.M., Bronstein, A.M., MC Ortega (7789433), JF Golding (7756883), Sharif, M., Bonsu, Angela, F de Melo (7789442), Ortega, M., Sharif, Mishaal, BM Seemungal (7738358), Bonsu, A., Rust, Heiko, Seemungal, Barry, Fluri, A-S., Golding, John, Arshad, Qadeer, de Melo, F., Bednarczuk, Nadja, A Bonsu (7789430), Ortega MC, Bronstein AM, Fluri AS, de Melo F, Chan J, Bonsu A, Arshad Q, Rust H, Kaski D, Golding JF, Bednarczuk NF, Seemungal BM, Sharif M   +51 more
core   +1 more source

Retrospective Grid Cells in the Medial Entorhinal Cortex Encode Past Paths During Spatial Navigation

Advanced Science, EarlyView.
Retrospective grid cells are identified in the medial entorhinal cortex, with spatial firing patterns that become most grid‐like when activity is projected onto recently traversed locations. Their coding loses spatial precision in darkness and is disrupted during assisted movement, indicating that entorhinal representations incorporate recent path ...
Ruojin Liu, Xin Yuan, Zilong He, Hong Jin, Jiayi Tian, Cong Chen, Yuanjing Liu, Xiang Zhang, Shidan Wen, Emilio Kropff, Chenglin Miao   +10 more
wiley   +1 more source

Frequency and intensity discrimination in children with cochlear implants

The Egyptian Journal of Otolaryngology
Background Frequency discrimination underlies more complicated auditory activities like speech comprehension and interpretation. However, intensity differences indicate how far apart noises are.
Nahed Mohamed Negm, Trandil Hassan Elmahalawy, Enaas Ahmad Kolkaila, Mona Ahmed Kotait   +3 more
doaj   +1 more source

Supplemental CO2 improves oxygen saturation, oxygen tension, and cerebral oxygenation in acutely hypoxic healthy subjects

Physiological Reports, 2020
Oxygen is viewed in medicine as the sole determinant of tissue oxygenation, though carbon dioxide homeostasis is equally important and clinically often ignored. The aims of this study were as follows: (a) to examine the effects of different acute hypoxic
Jan Stepanek, Ryan A. Dunn, Gaurav N. Pradhan, Michael J. Cevette   +3 more
doaj   +1 more source

Suppressing Photothermal Artifacts in Flexible Fluorescent Fiber‐Optic Sensors for Accurate and Precise In Situ Temperature Monitoring

Advanced Science, EarlyView.
A partial‐inner‐cladding optical fiber (PICOF) is developed to suppress photothermal artifacts in fluorescent fiber‐optic thermometry by isolating the sensing layer from regions prone to photothermal effects. This structural design strategy enables high‐fidelity operation at elevated excitation power, achieving high accuracy (maximum absolute error ...
Sijie Su, Jinjian Yu, Pengyuan Dong, Xin Wang, Jing Lyu, Jiulin Gan, Enhai Song, Qinyuan Zhang   +7 more
wiley   +1 more source