Results 121 to 130 of about 34,579 (255)

Scan for Success? Number Needed to Scan and Management Changes in Preoperative Otosclerosis: Quantitative Analysis

open access: yesOtolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To quantify the cumulative number of images needed to scan (NNS) with preoperative high‐resolution temporal bone computed tomography (HR‐TBCT) to yield a change in management in patients undergoing primary stapes surgery for otosclerosis‐related hearing loss. Study Design Retrospective cohort.
Omer J. Ungar   +8 more
wiley   +1 more source

A Protocol for Reconstructing Complex Lateral Skull Base Defects: Two Decades of Tertiary Care Experience

open access: yesOtolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To describe a multidisciplinary protocol for the resection and reconstruction of complex lateral skull base pathology, based on over two decades of experience in a high‐volume tertiary referral center in the United Kingdom. Study Design Retrospective descriptive analysis of institutional practice. Setting A high‐volume tertiary skull
Muhammad Umar Farooq   +8 more
wiley   +1 more source

CHARGE Syndrome: What an Otolaryngologist Should Know—A Systematic Review and Meta‐Analysis

open access: yesOtolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To synthesize the prevalence of otolaryngologic manifestations in CHARGE syndrome (CS) to support otolaryngologists in delivering comprehensive management. Data Sources PubMed/MEDLINE, Embase, and Google Scholar were searched for English‐ and French‐language studies published from January 1980 through January 2025.
Camille Caron   +5 more
wiley   +1 more source

The Audiologic and Otolaryngologic Phenotype in WHIM Syndrome

open access: yesOtolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective WHIM syndrome (warts, hypogammaglobulinemia, infections, and myelokathexis syndrome) is an ultra‐rare primary immunodeficiency disease caused by autosomal dominant hyperfunctional mutations in the chemokine receptor CXCR4. Otolaryngologists are frequently consulted to evaluate WHIM patients because of recurrent acute ear and sinus ...
Christopher K. Zalewski   +7 more
wiley   +1 more source

Molecular Biomarkers in Meniere's Disease: A Scoping Review of Current Evidence

open access: yesOtolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective Meniere's disease is a complex chronic inner ear condition that is characterized by vertigo, tinnitus, aural fullness, and progressive hearing loss. Currently, diagnostic strategies remain symptom‐driven, and treatments focus on management of discrete episodes rather than targeting underlying pathophysiology.
Hamza Kamran   +3 more
wiley   +1 more source

Long‐term outcomes of haploidentical hematopoietic stem cell transplantation with antithymocyte globulin–based myeloablative conditioning in pediatric refractory or relapsed non‐Hodgkin lymphoma

open access: yesPediatric Investigation, EarlyView.
Single‐center retrospective data showed that ATG‐based myeloablative haploidentical hematopoietic stem cell transplantation provides durable remission and favorable long‐term survival in children with refractory/relapsed non‐Hodgkin lymphoma, achieving high engraftment rates, low relapse incidence, and acceptable toxicity.
Chenguang Jia   +12 more
wiley   +1 more source

Effect of a virtual walking and therapeutic exercise‐based intervention on gait and balance in people with incomplete spinal cord injury

open access: yesPM&R, EarlyView.
Abstract Background People with spinal cord injury (SCI) experience sensory and motor impairments that often require exercise‐based treatments. However, these interventions are challenging due to limited active mobility. Novel rehabilitation approaches, such as those targeting the mirror neuron system, could offer additional benefits.
Sara Mollà‐Casanova   +6 more
wiley   +1 more source

Effect of video‐based game therapy on activation of scapular muscles in children with thoracic hyperkyphosis

open access: yesPM&R, EarlyView.
Abstract Background Game‐based rehabilitation has been shown to support motor control and muscle activation in children; therefore, video‐based gaming may represent a promising rehabilitation approach for targeting scapular muscles. Objective To examine the effects of video‐based game therapy on scapular muscle activation, strength, and upper extremity
Kubra Kardes   +2 more
wiley   +1 more source

Sodium Ions Affect GPR17 Conformational States and Functionality

open access: yesProteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Sodium is an allosteric modulator of several class‐A GPCR regulating active versus inactive conformation state and may be a critical issue for the optimization of crystallization procedures. Herein, the role of Na+ in the regulation of GPR17 conformational states was studied through MD simulations of GPR17 wild‐type and mutated on two ...
Luca Palazzolo   +6 more
wiley   +1 more source

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