Results 201 to 210 of about 9,405,086 (395)

Mitochondrial Ca2+ overload is a pivotal risk factor for lethal ventricular arrhythmias due to the oxidation of mitochondrial respirasome and energetic failure

British Journal of Pharmacology, EarlyView.
The data that support the findings of this study are available from the corresponding author upon reasonable request. Some data may not be made available because of privacy or ethical restrictions. Background and Purpose Ventricular arrhythmias are a leading cause of death among patients with cardiovascular diseases and are associated with elevated ...
Felipe de Jesús Salazar‐Ramírez, Luis Alberto Luévano‐Martínez, Abraham Méndez‐Fernández, Judith Bernal‐Ramírez, Carolina A. Morales‐Ochoa, Christian Silva‐Platas, Alfredo Cabrera‐Orefice, Ana C. Murrieta, José Luis Velasco‐Bolom, Gricelda Mendiola‐Garza, Flavio Contreras‐Torres, Guillermo Torre‐Amione, Ernesto A. Aiello, Gerardo García‐Rivas   +13 more
wiley   +1 more source

Molecular basis for a pore block of Tentonin 3 expressed in HEK293 cells by a conopeptide, NMB‐1

British Journal of Pharmacology, EarlyView.
Background and Purpose Tentonin 3 (TTN3/TMEM150C) is a mechanosensitive ion channel that plays critical roles in mechanotransduction processes. TTN3 forms a tetramer with a predicted rectangular shape and a central pore. A conotoxin ρ‐TIA and its synthetic analog, noxious mechanosensation blocker 1 (NMB‐1), were initially developed to inhibit slowly ...
Sujin Lim, Junhyuk Woo, Sungmin Pak, Joonho Paik, Gyu‐Sang Hong, Ji Hun Wi, Sanghee Lee, Cristina Fenollar‐Ferrer, Kyungreem Han, Young Kee Shin, Uhtaek Oh   +10 more
wiley   +1 more source

Motion sickness susceptibility under weightless and hypergravity conditions generated by parabolic flight [PDF]

Motion sickness susceptibility under weightless and hypergravity conditions generated by parabolic ...
Graybiel, A., Kellogg, R. S., Miller, E. F., II, Odonnell, R. D.   +3 more
core   +1 more source

Editorial: Challenges and current research status of vertigo/vestibular diseases, volume II. [PDF]

Front Neurol
Wang J, Castellucci A, Axer H, Zhang S.
europepmc   +1 more source

Biallelic RFC1 Expansions Are a Rare Cause of Early‐Onset and Familial Parkinson's Disease

Clinical Genetics, EarlyView.
Biallelic pathogenic expansions in RFC1 contribute to the genetic etiology of PD, with a frequency similar to that of other known autosomal recessive PD genes. RFC1‐positive PD is currently not clinically distinguishable from RFC1‐negative PD, but genetic background may play a role in future therapies or other interventions.
Anja Kovanda, Lara Šušmelj, Helena Jaklič, Tadeja Lukežič, Aleš Maver, Igor Petrovic, Natasa Dragasevic Miskovic, Marina Svetel, Valentino Rački, Vladimira Vuletič, Ivana Novakovic, Borut Peterlin   +11 more
wiley   +1 more source

Proposed diagnostic criteria for cerebellar ataxia with neuropathy and vestibular areflexia syndrome (CANVAS)

Neurology Clinical Practice, 2016
D. Szmulewicz, L. Roberts, C. Mclean, H. MacDougall, G. M. Halmágyi, E. Storey   +5 more
semanticscholar   +1 more source

Liquid–Liquid Phase Separation in Major Hallmarks of Cancer

Cell Proliferation, EarlyView.
Aberrant condensates formed through phase separation are involved in the dysregulation of various critical cellular processes, including genome stability, transcriptional regulation and signal transduction, thereby promoting malignant transformation and the acquisition of multiple cancer hallmarks.
Chen‐chen Xie, Ting Wang, Xin‐ran Liu, Yan Wang, Qin Dang, Tian Ding, Jia‐qi Xu, Xian‐jun Yu, Hai Lin, Xiao‐wu Xu, Yi Qin   +10 more
wiley   +1 more source

Epidemiological Case-control-study on Meniere's Disease Conducted by the Vestibular Disorders Research Committee of Japan in 1990

, 1991
Yukio Watanabe, Kanemasa Mizukoshi, Hajime Nakagawa, Hideya Ohi, Hideo Shoujaku, Satsuki Yasumura, Kimihiro Nakae, Masaaki Kitahara, Yoshiro Yazawa, Isamu Watanabe   +9 more
openalex   +2 more sources

Audio-vestibular and radiological analysis in Meniere’s disease

, 2022
Arzu Kırbaç, Şaziye Armağan İncesulu, Uğur Toprak, Hamdı Caklı, Hülya Özen, Suzan Şaylısoy   +5 more
openalex   +1 more source

Acute neurologic presentation of a 2‐year‐old standardbred colt with multicentric diffuse large B cell lymphoma

Equine Veterinary Education, EarlyView.
Summary Lymphoma in horses is uncommon and rarely diagnosed as a cause of ataxia. This case report describes a 2‐year‐old Standardbred cryptorchid colt who presented with acute onset of grade 3–4/5 spinal ataxia in all four limbs, with the hindlimbs more severely affected than forelimbs and severe proprioceptive deficits.
K. MacMillan, J. Burns, E. John, M. Buote   +3 more
wiley   +1 more source