Results 121 to 130 of about 654,150 (253)

Psychiatric and Neurodevelopmental Outcomes in Swedish Children With Hearing Loss due to Congenital Cytomegalovirus Infection: A Cross‐Sectional Study

Acta Paediatrica, EarlyView.
ABSTRACT Aim To investigate parent‐reported psychiatric, neurodevelopmental and adaptive functioning outcomes in children with congenital cytomegalovirus (cCMV)‐related sensorineural hearing loss. Methods Parents of children aged 5–12 years were recruited nationwide in Sweden into three groups: children with congenital cytomegalovirus‐related ...
A. Michel Sandström, E. Karltorp, U. Löfkvist   +2 more
wiley   +1 more source

Investigation of the mechanisms and modulation of irinotecan‐induced emesis in Suncus murinus

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Irinotecan is a widely used chemotherapeutic agent that frequently causes nausea and emesis. Its emetic mechanism of action is poorly understood and the choice of drugs to reduce nausea and emesis is largely empirical. Experimental Approach Using Suncus murinus, we examined (i) the dose–response and temporal profile of ...
Zengbing Lu, Julia Y. H. Liu, Yasuhiro Nakagami, Zitong Li, Xiaofei Huang, Man P. Ngan, Dexuan Cui, John A. Rudd   +7 more
wiley   +1 more source

Depressive and Anxiety Symptoms in Vestibular Migraine and Probable Vestibular Migraine

Clinical Otolaryngology, EarlyView.
ABSTRACT Introduction It has been previously reported that patients with vestibular migraine (VM) are more prone to anxiety and depressive symptoms. However, the association between the pathophysiology of VM and anxiety and depressive symptoms is still unclear.
Chisato Fujimoto, Naoko Ogata, Kento Koda, Kentaro Ichijo, Mineko Oka, Makoto Kinoshita, Kenji Kondo   +6 more
wiley   +1 more source

Evaluation of vestibular function in normal hearing adults with and without tinnitus

The Egyptian Journal of Otolaryngology
Background Tinnitus may occur in individuals with normal hearing and has increasingly been associated with subclinical vestibular dysfunction. The close anatomical relationship between the auditory and vestibular systems suggests that vestibular ...
Charu, Mukesh Sharma
doaj   +1 more source

Exploring the Vestibular–Cognitive Axis: A Case–Control Study of BACE1 rs638405 and Cognitive Vulnerability in Vestibular Dysfunction

Background:Alzheimer’s disease (AD) is a leading cause of cognitive decline worldwide and involves complex interactions between genetic, neurodegenerative, and environmental factors [1–3].
Gorgiladze, Keso, Vashadze, Shorena, Kekenadze, Mariam, Saparidze, Ketevan   +3 more
core   +1 more source

Physical therapy interventions for children and adolescents with myelomeningocele: A systematic review

Developmental Medicine &Child Neurology, EarlyView.
Abstract Aim To systematically review the current evidence on physical therapy interventions for children and adolescents with myelomeningocele, the most complex and common presentation of spina bifida, to explore intervention components and the outcomes according to International Classification of Functioning, Disability and Health (ICF) domains, and ...
Lorena Costa Ferreira, Isabella Saraiva Christovão, Robert J. Palisano, Ana Cristina Resende Camargos   +3 more
wiley   +1 more source

DiaActive protocol: A randomized controlled trial of cognitive‐motor multicomponent exercise to reduce fall rate in older adults with diabetes

Diabetic Medicine, EarlyView.
Abstract Introduction Older adults with diabetes have an increased risk of falls due to neuropathy, impaired bone health and cardiovascular disease, resulting in significant morbidity and mortality. Conventional fall‐prevention programmes primarily target strength and balance, while cognitive‐motor integration, essential for safe mobility in complex ...
Aksayan Arunanthy Mahalingasivam, Asger Ahlmann Bech, Peter Vestergaard, Martin Grønbech Jørgensen, Nicklas Højgaard‐Hessellund Rasmussen   +4 more
wiley   +1 more source

Modulation of sebocyte function in acne: A pathway‐inclusive review

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Acne is multifactorial, with the sebocyte acting as a central immunometabolic hub linking lipogenic, inflammatory, hormonal and barrier pathways. Mapping established and investigational therapies onto this sebocyte‐centred model offers a mechanism‐based framework that complements existing treatment paradigms and may guide more targeted, antibiotic ...
Christos C. Zouboulis, Apostolos Pappas, Katja Martin, Mauro Picardo   +3 more
wiley   +1 more source

Vestibular hair cells are more prone to damage by excessive acceleration insult in the mouse with KCNQ4 dysfunction

Scientific Reports
KCNQ4 is a voltage-gated K+ channel was reported to distribute over the basolateral surface of type 1 vestibular hair cell and/or inner surface of calyx and heminode of the vestibular nerve connected to the type 1 vestibular hair cells of the inner ear ...
Hansol Hong, Eun Ji Koo, Yesai Park, Gabae Song, Sun Young Joo, Jung Ah Kim, Heon Yung Gee, Jinsei Jung, Kangyoon Park, Gyu Cheol Han, Jae Young Choie, Sung Huhn Kim   +11 more
doaj   +1 more source

Cyclin‐dependent kinase 13 is indispensable for normal mouse heart development

Journal of Anatomy, Volume 246, Issue 4, Page 616-630, April 2025.
Congenital heart disease (CHD) is the most common defect in live births. The role of cyclin‐dependent kinase (CDK13) in cardiogenesis and CHD was studied using a transgenic mouse model (Cdk13tm1b) carrying deletion of exons 3 and 4, causing loss of function.
Qazi Waheed‐Ullah, Anna Wilsdon, Aseel Abbad, Sophie Rochette, Frances Bu'Lock, Asma Ali Saed, Marc‐Phillip Hitz, J. David Brook, Siobhan Loughna   +8 more
wiley   +1 more source