Results 141 to 150 of about 28,742 (262)

Jervell and Lange‐Nielsen Syndrome Related Clinical Genetics and Experimental Models

Pediatric Discovery, EarlyView.
ABSTRACT Jervell and Lange‐Nielsen syndrome (JLNS) is defined by electrocardiographic QT prolongation and sensorineural hearing loss, caused by homozygous or compound heterozygous variants in KCNQ1 and/or KCNE1. KCNQ1 encodes the alpha subunit Kv7.1 of the ion channels accountable for slow delayed rectifier potassium currents (IKs), whereas KCNE1 ...
Yafei Zhou, Christopher L.‐H. Huang, Ying Yang, Yanmin Zhang   +3 more
wiley   +1 more source

Analysis of balance in adults with chronic axial spinal pain receiving medial branch block or radiofrequency ablation procedures

PM&R, EarlyView.
Abstract Background Medial branch blocks (MBB) and radiofrequency ablations (RFA) are common diagnostic, prognostic, and interventional procedures performed for the management of cervical and lumbar spine facetogenic pain. Although these procedures have established utility as pain management strategies, it is unclear if the disruption in function of ...
Matthew Carter, John D Ralston, Robert Burnham, Jennifer Laxshimalla, Lisa Jasper, JuliAnn Thai, Ashley D Smith   +6 more
wiley   +1 more source

Objective oculomotor, vestibular, reaction time, and cognitive signatures of vestibular migraine. [PDF]

Front Neurol
Ceriani CEJ, Braverman A, Kiderman A.
europepmc   +1 more source

Effect of a virtual walking and therapeutic exercise‐based intervention on gait and balance in people with incomplete spinal cord injury

PM&R, EarlyView.
Abstract Background People with spinal cord injury (SCI) experience sensory and motor impairments that often require exercise‐based treatments. However, these interventions are challenging due to limited active mobility. Novel rehabilitation approaches, such as those targeting the mirror neuron system, could offer additional benefits.
Sara Mollà‐Casanova, Elena Muñoz‐Gómez, Núria Sempere‐Rubio, Noemí Moreno‐Segura, Marta Inglés, Luis‐Millán González, Pilar Serra‐Añó   +6 more
wiley   +1 more source

A Case of Functional Movement Disorder Preceding Right Temporal Predominant Frontotemporal Degeneration

Movement Disorders Clinical Practice, EarlyView.
Isis So, Aditya Murgai, Elizabeth C. Finger, Miguel Restrepo‐Martinez   +3 more
wiley   +1 more source

Flavonoids in Nasal Therapeutics: Biological Activities, Delivery Challenges, and Formulation Strategies–A Systematic Review

Phytotherapy Research, EarlyView.
Overview of the therapeutic potential of flavonoids in nasal delivery systems, highlighting their benefits to the human nasal cavity, and applications in the treatment of respiratory and brain‐related diseases. ABSTRACT Flavonoids represent a significant group of secondary metabolites.
Jeniffer Viviana Ramirez Hernández, Sara Elis Bianchi, Flávia Nathiely Silveira Fachel, Elizandra Braganhol, Sheila Porto de Matos, Valquíria Linck Bassani   +5 more
wiley   +1 more source

Characteristics of auditory and vestibular symptoms in patients with Meniere's disease. [PDF]

Braz J Otorhinolaryngol
Klančnik M, Radoš M, Ivanišević P, Cikojević D, Čolović Z.   +4 more
europepmc   +1 more source

Progress On Sensorineural Hearing Loss: Mechanisms and Therapies

Sensory Neuroscience, EarlyView.
ABSTRACT Hearing loss is the most common disabling disease among humans, which adversely affects human health. Sensorineural hearing loss (SNHL) accounting for approximately 63% of all hearing loss cases. SNHL may be classified into age‐related hearing loss (ARHL), drug‐induced hearing loss (DIHL), noise‐induced hearing loss (NIHL), and sudden ...
Yuan Zhang, Shen Li, Yangfan Zhou, Duopin Li, Junru Ding, Ruifeng Qiao, Yutian Chen, Fanglei Ye, Le Wang, Peipei Li   +9 more
wiley   +1 more source

Vestibular and Ocular Motor Phenotype in a Case of Paraneoplastic Autoimmune Kelch-Like Protein-11 Encephalitis. [PDF]

Neurol Neuroimmunol Neuroinflamm
Schwarz FK, Höftberger R, Endmayr V, Lukac I, Rommer PS, Rath J, Berger T, Milenkovic I, Wiest G.   +8 more
europepmc   +1 more source

AMPKα Silencing Prevents Kanamycin‐Induced Ototoxicity in an Acute Mouse Model

Sensory Neuroscience, EarlyView.
Kanamycin plus furosemide (KM + FU) treatment (acute ototoxic model) causes AMPKα activation and rapidly induces cochlear outer hair cell (OHC) loss. Silencing AMPKα1 via posterior semicircular canal injection 48 h before KM + FU treatment reduces this damage, preserving OHCs and hearing.
Shengyu Zou, Fan Wu, Qiaojun Fang, Zuhong He, Hongguo Su, Shan Xu, Su‐Hua Sha   +6 more
wiley   +1 more source