Results 191 to 200 of about 28,742 (262)

Multivalent antibody‐based conjugates as new tools for tailored modulation of G protein–coupled receptors

British Journal of Pharmacology, EarlyView.
The G protein–coupled receptor (GPCR) superfamily consists of the most common targets of approved drugs. Targeting GPCRs offers appealing avenues for therapeutic development. Antibodies and their fragments, such as single‐domain antibodies (VHHs or nanobodies), have emerged as useful alternatives to small molecule pharmacophores as building blocks in ...
Shivani Sachdev, Ross W. Cheloha
wiley   +1 more source

Optimal Assessment of Vestibular Function for Predicting Clinical Outcomes in Patients Diagnosed with Sudden Deafness. [PDF]

J Otolaryngol Head Neck Surg
Huang AP, Zhao LJ, Huang SJ, Pan CZ, Zhou Y, Wang Y, Qian SX.   +6 more
europepmc   +1 more source

Genetic Landscape of Hearing Loss in Brazilian Patients Reveals Population‐Specific Variants and Clinical Correlations

Clinical Genetics, EarlyView.
The Burden: Hearing loss (HL) is the most prevalent sensory disorder globally, affecting 1.5 million individuals in Brazil. The Gap: While > 150 genes are linked to HL, the genetic architecture in underrepresented populations like Brazil is poorly defined. The Problem: This lack of data limits diagnostic yield and the application of precision medicine.
Stella Diogo‐Cavassana, Danillo Alencar‐Coutinho, Rafaella Abreu‐Oberhuber, Maria Eduarda Paramo‐Neto, Jeanne Oiticica, Ricardo Ferreira Bento, Ana Carla Batissoco, Karina Lezirovitz   +7 more
wiley   +1 more source

Selective Otolithic and Semicircular Canal Dysfunction: Insights from VEMP and vHIT. [PDF]

J Clin Med
Skacik P, Sivak S, Kurca E.
europepmc   +1 more source

The Role of the Keratinized Mucosa in Peri‐Implant Diseases Onset and Brushing Discomfort: A 10‐Year Follow‐Up

Clinical Oral Implants Research, EarlyView.
ABSTRACT Objectives To evaluate the effect of narrow (< 2 mm) and wide (≥ 2 mm) keratinized mucosa (KM) over 10 years on peri‐implant diagnosis and brushing discomfort. Materials and Methods Eighty patients were initially evaluated. Demographic data, modified plaque index (mPI)/plaque index (PI), probing depth (PD), clinical attachment level (CAL ...
Fernanda Angelio da Costa Deller, Jeniffer Perussolo, André Barbisan de Souza, Ricardo Puziol de Oliveira, Flávia Matarazzo, Maurício G Araújo   +5 more
wiley   +1 more source

Critical evaluation of the benefits and limitations of foam posturography in vestibular disorders: a narrative review. [PDF]

Front Neurol
Patel M, Walter C, Fransson PA.
europepmc   +1 more source

Augmented Reality Improves Accuracy of Dynamic Computer‐Assisted Implant Surgery: An In Vitro Analysis

Clinical Oral Implants Research, EarlyView.
ABSTRACT Objective To assess the accuracy of dynamic computer‐assisted implant surgery (dCAIS) performed with and without augmented reality (AR) smart‐glasses visualization under standardized laboratory conditions. Materials and Methods A standardized typodont model with bounded and unbounded edentulous spaces was prepared to receive polyurethane ...
Arndt Guentsch, Shengtong Han
wiley   +1 more source

Personalized Vestibular Rehabilitation in Persistent Postural-Perceptual Dizziness (PPPD), Unilateral and Bilateral Vestibular Dysfunction: A Comparative Study. [PDF]

J Pers Med
Picciotti PM, Rolesi R, Rossi G, Oliveto G, Galli J.   +4 more
europepmc   +1 more source

A Space for “us”: Sensory Ethnography as an Embodied Method in Food Anthropology

Culture, Agriculture, Food and Environment, EarlyView.
ABSTRACT Minority communities are vulnerable to poor health due to diet‐related diseases, a fact that food anthropologists have long discussed. This is also something that the individuals living within constrained food environments are aware of and challenge intellectually and on an embodied basis through food choices based on cultural and physical ...
Carolyn Mason
wiley   +1 more source

Internet-based vestibular rehabilitation versus written instructions after acute vertigo: A randomised controlled trial. [PDF]

PLoS One
Surano S, Lindell E, Mathé J, Davidsson H, Tomanovic T, Bjurman M, Faergemann E, Ledin T, Rostmark A, Grip H, Öhberg F, Granåsen G, Salzer J.   +12 more
europepmc   +1 more source