Functional compensation between clarin‐1 and clarin‐2 in cochlear hair cells. Hearing loss associated with CLRN1 mutations shows striking phenotypic variability; however, the underlying mechanisms remain poorly understood. This study reveals that clarin‐1 and clarin‐2 function cooperatively in cochlear hair cells to sustain mechanoelectrical ...
Maureen Wentling +17 more
wiley +1 more source
Morphological correlation between caloric tests and vestibular hydrops in Ménière's disease using intravenous Gd enhanced inner ear MRI. [PDF]
The purpose of this study was to prove the hypothesis that caloric response in Ménière's disease (MD) is reduced by hydropic expansion of the vestibular labyrinth, not by vestibular hypofunction, by evaluating the correlation morphologically using an ...
Ji Eun Choi +7 more
doaj +1 more source
Functional correlates of optic flow motion processing in Parkinson’s disease [PDF]
The visual input created by the relative motion between an individual and the environment, also called optic flow, influences the sense of self-motion, postural orientation, veering of gait, and visuospatial cognition.
Cronin-Golomb, Alice +6 more
core +5 more sources
ABSTRACT Objective In the last two decades, transnasal endoscopic surgery (TES) has become pivotal in the management of sinonasal tumors. This approach involves a multiblock tumor resection, adding complexity to the interpretation of surgical margins after pathological examination.
Piergiorgio Gaudioso +14 more
wiley +1 more source
Prevalence of abnormalities in vestibular function and balance among HIV-seropositive and HIV-seronegative women and men. [PDF]
Most HIV-seropositive subjects in western countries receive highly active antiretroviral therapy (HAART). Although many aspects of their health have been studied, little is known about their vestibular and balance function.
Helen S Cohen +6 more
doaj +1 more source
Aplicações dos potenciais evocados miogênicos vestibulares: revisão sistemática de literatura
RESUMO Objetivos Revisar a literatura científica sobre as principais técnicas usadas para gerar o potencial evocado miogênico vestibular (VEMP) e suas aplicações clínicas.
Tatiana Rocha Silva +6 more
doaj +1 more source
Neurogenesis and astrogenesis contribute to vestibular compensation in the neurectomized adult cat: cellular and behavioral evidence [PDF]
Neurogenesis occurs in some regions of the adult mammalian brain and gives rise to neurons integrated into functional networks. In pathological or postlesional conditions, neurogenesis and astrogenesis can also occur, as demonstrated in the deafferented ...
Brahim Tighilet +4 more
core +1 more source
Intraspecific variation of cochlear morphology in bowhead and beluga whales
Abstract The bony labyrinth of the petrosal bone, a distinctive feature of mammal skulls, is often identified in micro‐computed tomography imaging to infer species' physiological and ecological traits. When done as part of a comparative study, one individual specimen is normally considered representative of a species, and intraspecific variation is ...
John Peacock, J. G. M. Thewissen
wiley +1 more source
Defective Tmprss3-Associated Hair Cell Degeneration in Inner Ear Organoids [PDF]
Mutations in the gene encoding the type II transmembrane protease 3 (TMPRSS3) cause human hearing loss, although the underlying mechanisms that result in TMPRSS3-related hearing loss are still unclear.
Alex, Alpha L. +8 more
core +1 more source
Statistical shape modeling of the human inner ear through micro‐computed tomography imaging
In this study, 54 cadaveric temporal bone specimens underwent high‐resolution micro‐CT imaging. Images were semi‐automatically segmented and converted to 3D surface mesh models for morphological measurement and analysis. Statistical shape models were created for the inner ear, cochlea, and vestibular system, as well as for sex‐ and side‐based subgroups.
Carmine Spedaliere +8 more
wiley +1 more source

