Recombinant Human Neuregulin1‐β1 Significantly Reduces Schwannoma Growth in Mice
Annals of Neurology, EarlyView.rhNRGβ1‐Replacement‐Therapy: Under physiological conditions, NRGβ1 is expressed on axons (in orange), where it activates ERBB2 receptors, facilitating successful nerve regeneration following injury. However, loss of NF2 leads to a reduction in NRGβ1‐expression and increased ErbB2 levels on Schwann cells (in green), which contributes to schwannoma ...
Julia P. Bischoff +7 more
wiley +1 more source
Vestibular schwannomas: Accuracy of tumor volume estimated by ice cream cone formula using thin-sliced MR images. [PDF]
PLoS ONE, 2018 We estimated the volume of vestibular schwannomas by an ice cream cone formula using thin-sliced magnetic resonance images (MRI) and compared the estimation accuracy among different estimating formulas and between different models.The study was approved ...
Hsing-Hao Ho +8 more
doaj +1 more source
Preserving normal facial nerve function and improving hearing outcome in large vestibular schwannomas with a combined approach: planned subtotal resection followed by gamma knife radiosurgery. [PDF]
, 2017 To perform planned subtotal resection followed by gamma knife surgery (GKRS) in a series of patients with large vestibular schwannoma (VS), aiming at an optimal functional outcome for facial and cochlear nerves.
Daniel, R.T. +7 more
core +2 more sources
Cold atmospheric plasma‐mediated tumor microenvironment remodeling for cancer treatment
BMEMat, EarlyView.Schematic presentation of CAP‐mediated TME remodeling. This review summarizes recent efforts in cold atmospheric plasma (CAP) application in cancer treatment, highlighting the anticancer potential of CAP, molecular mechanisms, and future perspectives for further improvement and clinical translation.
Israr Khan +8 more
wiley +1 more source
Gamma Knife radiosurgery for vestibular schwannoma: case report and review of the literature
World Journal of Surgical Oncology, 2009 Vestibular schwannomas, also called acoustic neuromas, are benign tumors of the vestibulocochlear nerve. Patients with these tumours almost always present with signs of hearing loss, and many also experience tinnitus, vertigo, and equilibrium problems ...
Fairbanks Robert K +7 more
doaj +1 more source
Technical considerations in a glossopharyngeal schwannoma
Interdisciplinary Neurosurgery, 2021 Glossopharyngeal schwannomas are relatively uncommon neoplasms.Their clinical presentation varies and may mimic a vestibular schwannoma.The differential diagnosis between vestibular schwannoma and glossopharyngeal schwannoma when tumor extends to ...
Oksana Zemskova +5 more
doaj +1 more source
How I Do It: Middle Fossa Approach of Facial Nerve Decompression
The Laryngoscope, EarlyView.We present a reproducible, stepwise middle fossa approach for facial nerve decompression focused on the labyrinthine segment, geniculate ganglion, and meatal foramen, with consistent anatomical landmarks to preserve hearing. The article and video detail patient setup, safe corridor creation, and retrograde drilling with practical tips to avoid cochlear
Stéphane Gargula +7 more
wiley +1 more source
Simultaneous Contralateral Vestibular Schwannoma and Middle Ear Paraganglioma Tumor [PDF]
, 2017 To the best of our knowledge, only 2 cases of a simultaneous contralateral vestibular schwannoma (VS) and middle ear paraganglioma (MEP) have previously been reported in literature.
Barbara, M +6 more
core +1 more source
Adjunctive Hyperbaric Oxygen Therapy or Intratympanic Steroids in Sudden Sensorineural Hearing Loss?
The Laryngoscope, EarlyView.Sudden sensorineural hearing loss is traditionally treated with steroids, either orally and/or via intratympanic injections, and hyperbaric oxygen treatment (HBOT) has resurged in popularity as an adjunctive therapy. The study has not found any additional treatment benefit with adjunctive concurrent HBOT; however, HBOT might be of value to patients ...
Jennifer L. Spiegel +9 more
wiley +1 more source
The extracisternal approach in vestibular schwannoma surgery and facial nerve preservation [PDF]
, 2014 The classical surgical technique for the resection of vestibular schwannomas (VS) has emphasized the microsurgical anatomy of cranial nerves. We believe that the focus on preservation of the arachnoid membrane may serve as a safe guide for tumor removal.
Beer-Furlan, Andre +5 more
core +3 more sources