Results 91 to 100 of about 112,219 (308)

The link of FOXO1 and FOXO4 transcription factors to development of the lens

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background The FOXOs regulate the transcription of many genes, including ones directly linked to pathways required for lens development. However, this transcription factor family has rarely been studied in the context of development, including the development of the lens.
Rifah N. Gheyas   +3 more
wiley   +1 more source

Plasticity of histamine H3 receptor expression and binding in the vestibular nuclei after labyrinthectomy in rat [PDF]

open access: yes, 2004
Background: In rat, deafferentation of one labyrinth (unilateral labyrinthectomy) results in a characteristic syndrome of ocular and motor postural disorders (e.g., barrel rotation, circling behavior, and spontaneous nystagmus). Behavioral recovery (e.g.,
Aarnisalo, Antti A.   +4 more
core   +2 more sources

Activation and inhibition of Notch signaling facilitate proliferative regeneration of sensory cells in adult mice

open access: yesEye &ENT Research, EarlyView.
Abstract Due to the limited regenerative capacity in adult mammals, the loss of vestibular hair cells (HCs) leads to balance disorders. In this study, we chronologically reprogrammed adult vestibular supporting cells (SCs) via bimodal regulation of Notch signaling, mimicking dynamic changes in Notch signaling during inner ear development. We found that
Shan Zeng   +5 more
wiley   +1 more source

Creativity and its link to epilepsy

open access: yesEpilepsia Open, EarlyView.
Abstract Creative thinking represents one of our highest‐order cognitive processes, involving multiple cortical structures and an intricate interplay between several cortical and subcortical networks. It results in novel ideas that translate to useful products or concepts. The evolutionary purpose of creativity is therefore apparent, as it advances our
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

Emotion regulation difficulties and differences in autism including demand‐avoidant presentations—A clinical review of research and models, and a proposed conceptual formulation: Neural‐preferencing locus of control (NP‐LOC)

open access: yesJCPP Advances, EarlyView.
Abstract Emotion regulation (ER) difficulties and differences in autism are well documented in both research and clinical literature, negatively impacting well‐being for autistic young people. Emotion dysregulation can significantly decrease access to opportunities to learn life skills and increase the risk of mental health problems in adulthood.
Nicky Greaves
wiley   +1 more source

Serum vitamin D concentration is inversely associated with matrix metalloproteinase‐9 level in periodontal diseases

open access: yesJournal of Periodontology, EarlyView.
Abstract Background The aim of this study was to investigate the potential association between vitamin D deficiency and matrix metalloproteinase‐9 (MMP‐9) levels in gingival crevicular fluid (GCF) across various periodontal health and disease statuses.
Yeşim Ayhan Yıldırım   +4 more
wiley   +1 more source

A Middle and Late Devensian sequence from the northern part of Kents Cavern (Devon, UK)

open access: yesJournal of Quaternary Science, EarlyView.
Abstract 1920s/30s excavation of a Middle Devensian sequence in the northern part of Kents Cavern recovered important Late Middle and Early Upper Palaeolithic archaeological material, including Britain's oldest known Homo sapiens remains. Questions remain about this material, including how it came to be in the cave.
Rob Dinnis   +11 more
wiley   +1 more source

Low‐Strip Dorsal Preservation Rhinoplasty Opens the Internal Nasal Valve in Tension Nose Deformity

open access: yesThe Laryngoscope, EarlyView.
The goal of this study was to evaluate the effect of dorsal preservation on internal nasal valve dimensions in noses with an overprojected cartilaginous septum. Ten postmortem human specimen heads with a tension nose deformity were imaged using ultra‐high‐resolution photon‐counting detector computed tomography, before and after low‐strip let down.
Floris V.W.J. van Zijl   +6 more
wiley   +1 more source

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