Block of NMDA receptor channels by endogenous neurosteroids: implications for the agonist induced conformational states of the channel vestibule [PDF]
N-methyl-D-aspartate receptors (NMDARs) mediate synaptic plasticity, and their dysfunction is implicated in multiple brain disorders. NMDARs can be allosterically modulated by numerous compounds, including endogenous neurosteroid pregnanolone sulfate ...
Vojtech Vyklicky +2 more
exaly +4 more sources
An Accessroy tragus on the nasal vestibule: A case report
An accessory tragus is a congenital defect involving malformation of the tragus. Rarely, it can be found in the nasal vestibule, where it can cause functional airway obstruction.
Ahmed Alsayed +2 more
doaj +2 more sources
The gods bestow life. New material for the study of divine processions in the Vestibule of the Chapel of Hatshepsut in Deir el-Bahari [PDF]
The decoration of the Vestibule of the Chapel of Hatshepsut in the queen’s temple in Deir el-Bahari resembles the decoration of the square antechamber known from the pyramid temples of the Old and Middle Kingdoms.
Edyta Kopp
doaj +2 more sources
Dissociated responses to caloric and head impulse stimulation in a case of isolated vestibule-lateral semicircular canal dysplasia [PDF]
Isolated vestibule-lateral semicircular canal dysplasia (LSCCD) is one of the most common inner ear malformations. We present a case of a 59-year-old patient with right vestibule-lateral canal dysplasia and a history of spontaneous vertigo spells without
Ricardo Wegmann-Vicuña +5 more
doaj +2 more sources
Drug-bound outward-facing conformation of a heterodimeric ABC exporter suggests a putative mechanism of drug translocation [PDF]
Multidrug transport by ATP binding cassette (ABC) exporters entails a mechanism to modulate drug affinity across the transport cycle. Here, we combine cryo-EM and molecular dynamics (MD) simulations to illuminate a lipid-competition mechanism to drive ...
Qingyu Tang +5 more
doaj +2 more sources
Ophiorrhiza shiqianensis (Rubiaceae), a new species from Guizhou, China [PDF]
A new species of the genus Ophiorrhiza L. (Rubiaceae), Ophiorrhiza shiqianensis L.D.Duan & Yun Lin, is described, illustrated and photographed from Shiqian County, Guizhou Province, South-western China.
Lin-Dong Duan, Yun Lin, Zhen Lu
doaj +3 more sources
The causes of vestibular dysfunction include the loss of hair cells (HCs), synapses beneath the HCs, and nerve fibers. 7, 8–dihydroxyflavone (DHF) mimics the physiological functions of brain-derived neurotrophic factor. We investigated the effects of the
Makoto Kinoshita +4 more
doaj +1 more source
A Comprehensive Literature Review on the Architecture of the Upper Labial Frena [PDF]
Over the past few years, various surgical procedures have evolved that focus on releasing the taut superior labial frena in infants, yet little is known about their normal or variant morphology despite the growing incidence of severe upper labial frenar
S Surraj +4 more
doaj +1 more source
Ce travail propose une réflexion sur les seuils métaphoriques du livre (son vestibule, ses portes de passage ou de clôture), en vue d’approfondir sur la conception du livre lui- même, ses fonctions et les problèmes de commercialisation, de création et de
Soledad Arredondo
doaj +1 more source
BackgroundMany endolymphatic hydrops (EH) MRI studies in the literature do not include a normal control group. Consequently, it remains unclear which outcome measure in EH MRI can most effectively distinguish between MD patients and normal controls ...
Tae-Soo Noh +6 more
doaj +1 more source

