Results 21 to 30 of about 2,422,248 (138)

Avaliação e reabilitação vestibular no indivíduo idoso

open access: yesRevista Brasileira de Geriatria e Gerontologia
Considerando a necessidade de propiciar melhora na qualidade de vida do idoso e a elevada incidência de queixas relacionadas aos transtornos de equilíbrio nessa faixa etária, este estudo teve como objetivo avaliar o equilíbrio estático e dinâmico de ...
Natália Daniela Rezende Mirallas   +4 more
doaj   +1 more source

Duplicate internal auditory canals with facial and vestibulocochlear nerve dysfunction

open access: yes, 2011
Objective:We report an extremely rare case of duplication of the internal auditory canal associated with dysfunction of both the facial and vestibulocochlear nerves.
A Abdullah, T Y Kew
core   +1 more source

Role of SoxE transcription factors in development and disease

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Sox8, Sox9, and Sox10 arose by multiple rounds of genome duplications from a single SoxE gene in ancestral vertebrates. In this review, we will briefly discuss the molecular structure and function of SoxE transcription factors and their evolutionary origin. We will then discuss their expression, function, and developmental disorders.
Merin Lawrence, Gerhard Schlosser
wiley   +1 more source

Autonomic and sensory nerve dysfunction in primary biliary cirrhosis [PDF]

open access: yes, 2004
AIM: Cardiovascular autonomic and peripheral sensory neuropathy is a known complication of chronic alcoholic and non-alcoholic liver diseases. We aimed to assess the prevalence and risk factors for peripheral sensory nerve and autonomic dysfunction using
Horváth, Andrea   +8 more
core   +1 more source

CHARGE Syndrome: What an Otolaryngologist Should Know—A Systematic Review and Meta‐Analysis

open access: yesOtolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To synthesize the prevalence of otolaryngologic manifestations in CHARGE syndrome (CS) to support otolaryngologists in delivering comprehensive management. Data Sources PubMed/MEDLINE, Embase, and Google Scholar were searched for English‐ and French‐language studies published from January 1980 through January 2025.
Camille Caron   +5 more
wiley   +1 more source

Willin, an upstream component of the Hippo signaling pathway, orchestrates mammalian peripheral nerve fibroblasts [PDF]

open access: yes, 2013
Willin/FRMD6 was first identified in the rat sciatic nerve, which is composed of neurons, Schwann cells, and fibroblasts. Willin is an upstream component of the Hippo signaling pathway, which results in the inactivation of the transcriptional coactivator
Tilston-Lünel, A.M.   +45 more
core   +2 more sources

CHARGE Syndrome: A Narrative Review and Update on Diagnosis, Assessment and Management

open access: yesJournal of Paediatrics and Child Health, EarlyView.
ABSTRACT Background CHARGE syndrome (CS) is a rare multisystemic genetic condition caused by a pathogenic variant in the DNA‐binding protein‐7 CHD7 gene. The condition affects the development of neural crest cells, which give rise to craniofacial structures, cranial nerves, ears, eyes and the heart, resulting in diverse and complex clinical features ...
Eleni M. van Gelder   +7 more
wiley   +1 more source

Partitioned Internal Auditory Canal: Association With Cochlear Aperture Anomalies

open access: yesThe Laryngoscope, Volume 136, Issue 10, Page 4416-4423, October 2026.
Partitioned internal auditory canal (IAC), defined by a bony septum separating the facial nerve from the cochleovestibular nerve, occurs significantly more often in ears with stenotic or atretic cochlear aperture. ABSTRACT Objective To investigate the association between partitioned internal auditory canal (IAC) and other inner ear abnormalities ...
Levent Sennaroğlu, Emel Tahir
wiley   +1 more source

Vestibular Paroxysmia Coexisting With Meige Syndrome: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT VP and MS are distinct clinical entities arising from the peripheral vestibular system and central extrapyramidal pathways, respectively. We report a rare case of a 69‐year‐old woman with coexistence of VP and MS. Individualized pharmacotherapy resolved vertigo and markedly improved blepharospasm.
Yanan Ding   +6 more
wiley   +1 more source

Timing‐Dependent Clearance of p16‐Positive Cells Mitigates Radiation‐Induced Accelerated Aging

open access: yesAging Cell, Volume 25, Issue 9, September 2026.
Genotoxic stress induces a progressive accelerated aging‐like phenotype driven by the delayed accumulation of p16Ink4a‐positive senescent cells. Selective clearance of these cells improves healthspan, tissue function, and survival only when initiated after senescent cells have accumulated, highlighting a critical therapeutic window for senescence ...
Karla Valdivieso   +15 more
wiley   +1 more source

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