Treatment of Vestibulodynia with Submucosal Injections of IncobotulinumtoxinA into Targeted Painful Points: An Open-Label Exploratory Study [PDF]
Toxins, 2023 The studies carried out to date on vulvodynia treatment with botulinum neurotoxin type A (BoNT/A) have followed generic injection protocols and reported contradictory outcomes on its effects.
Paula Villa-Muñoz +4 more
doaj +2 more sources
Efficacy and Safety of Topical 5% Cannabidiol Plus Myrcene for the Treatment of Vestibulodynia: A Multi-Centric Randomized Controlled Trial [PDF]
BiomedicinesBackground/Objectives: Vestibulodynia is the prevalent form of vulvodynia, causing burning, irritation, rawness, and dyspareunia sensations. This sensory abnormality suggests sensitization to neuropathic pain.
Filippo Murina +6 more
doaj +2 more sources
Preferred physical characteristics of lidocaine thin film for women with vestibulodynia [PDF]
Frontiers in Pain Research, 2023 IntroductionVestibulodynia (VBD) is the most common cause of sexual pain in the United States, affecting up to 15% of reproductive-aged women during their lifetime with limited treatment options.
R. Gina Silverstein +7 more
doaj +2 more sources
Distinct neural signaling characteristics between fibromyalgia and provoked vestibulodynia revealed by means of functional magnetic resonance imaging in the brainstem and spinal cord [PDF]
Frontiers in Pain Research, 2023 IntroductionFibromyalgia and provoked vestibulodynia are two chronic pain conditions that disproportionately affect women. The mechanisms underlying the pain in these conditions are still poorly understood, but there is speculation that both may be ...
Gabriela Ioachim +9 more
doaj +2 more sources
Effectiveness of Two Transcutaneous Electrical Nerve Stimulation (TENS) Protocols in Women with Provoked Vestibulodynia: A Randomized Controlled Trial [PDF]
Medical Sciences, 2023 Background: Vestibulodynia (VBD) is the most common form of vulvodynia. Because VBD is a pain disorder, transcutaneous electrical nerve stimulation (TENS) can be used as treatment.
Filippo Murina +3 more
doaj +2 more sources
Immune activation enhances epithelial nerve growth in provoked vestibulodynia [PDF]
American Journal of Obstetrics and Gynecology, 2016 BACKGROUND: Provoked vestibulodynia manifests as allodynia of the vulvar vestibular mucosa. The exact mechanisms that result in altered pain sensation are unknown.
Anders Paetau, Seppo Meri, Eija kalso
exaly +2 more sources
Localized provoked vulvodynia as an immune-mediated inflammatory disease: rationale for a new line of research [PDF]
Frontiers in Cellular and Infection MicrobiologyLocalized provoked vulvodynia (LPV), also called vulvar vestibulitis or provoked vestibulodynia, is a major cause of dyspareunia that severely impacts sexual health.
Jorma Paavonen, Robert C. Brunham
doaj +2 more sources
Clinical Evidence Regarding Spermidine–Hyaluronate Gel as a Novel Therapeutic Strategy in Vestibulodynia Management [PDF]
PharmaceuticsBackground: Vestibulodynia (VBD) represents a summation and overlapping of trigger factors (infections, hormonal disturbances, allergies, genetic aspects, psychological vulnerability, and others) with broad individual variability.
Filippo Murina +9 more
doaj +2 more sources
Use of botulinum toxin in aesthetic medicine and gynaecology: current approaches, controversies, and future directions [PDF]
Menopause Review, 2023 This review looks at the use of botulinum toxin in the gynaecological field with the aim of determining what needs to be further investigated to achieve a standardized application.
Andrea Etrusco +5 more
doaj +2 more sources
Understanding Patient Experiences of Vulvodynia Through Reddit: Qualitative Analysis [PDF]
JMIR InfodemiologyBackgroundVulvodynia is a chronic vulvar pain condition affecting up to 25% of the US population. However, diagnosis and effective treatment remain elusive.
Aurora J Grutman +8 more
doaj +2 more sources