Results 101 to 110 of about 92,194 (251)

Integrated Single‐Nucleus Multi‐Omics Atlases Reveal Lineage Plasticity and Regulatory Networks of Luminal Epithelial Cells During Mammary Gland Lactation and Involution

Advanced Science, EarlyView.
This study integrates single‐cell multi‐omics, spatial transcriptomics, and cross‐species comparative analyses to systematically characterize the cellular composition and differentiation trajectories of goat mammary epithelial cells, along with the gene regulatory networks and intercellular communication mechanisms governing these trajectories, thereby
Xiaoru Yan, Xiaoyu Mi, Guanghui Tan, Xinmei Li, Zhenliang Zhu, Zhenyu Wei, Huimei Fan, Yamei Wu, Tao Shi, Lingzhao Fang, Yuanpeng Gao, Yu Wang, Jun Liu   +12 more
wiley   +1 more source

Validation of the burnout assessment tool-core symptoms in Spanish veterinarians, sex invariance, and cutoff points

Frontiers in Veterinary Science
Notably, most studies on burnout in Veterinary Medicine have used the Maslach Burnout Inventory; however, it has limitations and does not evaluate severe burnout. Therefore, in this study, we validated the Burnout Assessment Tool-Core Symptoms (BAT-C) in
Amparo Osca, Jesús Barrado, Lorena Millán   +2 more
doaj   +1 more source

Microsporidia

, 2014
The current mandate of the OIE is to improve animal health, veterinary public health and animal welfare worldwide. The OIE considers bee mortality and bee diseases to be a priority...The publication of this book is, therefore, in line with the OIE ...
Sveriges lantbruksuniversitet., Fries, Ingemar,   +1 more
core  

Computation and Structure‐Guided Arginine Scanning Engineers a Hyperactive AP Endonuclease for Multiplex Viral RNA Sensing

Advanced Science, EarlyView.
Computational and structure‐guided arginine scanning rewires the DNA‐binding interface of APE1 to create APE1‐Evo, a hyperactive yet specific AP endonuclease. Integrated into the NAPTUNE‐V2.0 cascade, APE1‐Evo enables amplification‐free, multiplex viral RNA sensing for dengue virus and influenza A/B, highlighting a general strategy for engineering ...
Junlan Wang, Ting Wu, Feizuo Wang, Boyang Wang, Xin Yu Wong, Senfeng Zhang, Shengsheng Ma, Yao Liu, Fangyao Yao, Zhifeng Zeng, Siyuan Yang, Kunming Liu, Qi Wang, Yilong Wang, Yunxiang Zang, Xiaolong Wang, Xingxu Huang, Shao Li, Quanquan Ji, Tao Hu, Chunyi Hu   +20 more
wiley   +1 more source

Veterinarians’ Perspectives on the Antimicrobial Resistance (AMR) Dashboard: A Survey of Needs and Preferences to Inform Development

Veterinary Sciences
Antimicrobial resistance (AMR) poses a significant global threat to human and animal health, necessitating robust surveillance and stewardship tools. While existing systems address aspects of veterinary AMR, a comprehensive, user-centric dashboard for U ...
Abraham Joseph Pellissery, Thomas Denagamage, Maura Pedersen, Subhashinie Kariyawasam   +3 more
doaj   +1 more source

An infographic on laboratory animal veterinarians

Background Laboratory animal veterinarians play a crucial role as a bridge between the ethical use of laboratory animals and the advancement of scientific and medical knowledge in biomedical research.
Jae-Hun Ahn, Seung-Yeon Kim, Jungmin Lee, Yu Gang Kim, Da In On, Hyunjhung Jhun, Je Kyung Seong, Young-Shin Joo, Yujin Kim, On Shim, Jun-Won Yun, Byeong-Cheol Kang, Kyoung-Sun Lee, Jiwon Lee, Jinha Jeon, Jae-eun Lee, Ji-Yeon Hwang, Ki Taek Nam, Jeong-Hwan Che, Insook Yang, Seung Hyun Oh, Bora Kim, Ji-Young Kim   +22 more
core   +1 more source

Genetic Ablation and Multi‐Omics Profiling Reveal CEP55 as a Key Driver of Tumorigenesis in Diverse Cancer Models

Advanced Science, EarlyView.
Genetic ablation of Cep55 in Pten‐deficient mouse models delays tumorigenesis. Integrated multi‐omics analyses (proteomics, phosphoproteomics, and spatial transcriptomics) reveal that CEP55 regulates oncogenic signaling (RAS/ERK, PI3K/AKT), integrin/FAK‐mediated adhesion, extracellular matrix (ECM) remodeling, and endocytosis.
Behnam Rashidieh, Yuanhao Yang, Amanda Louise Bain, Phillip Theron, Catharina Vosloo, Sahar Keshvari, Parinaz Ahangar, Brydie Bowden, Simon M. Tria, Ben B. Wang, Sandra Isenmann, Nicholas J. Westra van Holthe, Zherui Xiong, Hani Vu, Sowmya Sharma, Asmerom Sengal, J. Alejandro Lopez, John Finnie, Antonella Papa, Pascal H.G. Duijf, Quan Nguyen, Pirjo M. Apaja, Kum Kum Khanna   +22 more
wiley   +1 more source

Challenges and Opportunities of Bacterial Vaccines as Alternatives to Antimicrobials in Swine Health Management: Insights from U.S. Veterinarians

Pathogens
Antimicrobial resistance (AMR) is a significant global health concern, and the use of antibiotics in livestock, including swine production, is a major contributor.
Xirui Zhang, Danqin Li, Michael D. Apley, Locke Karriker, Joseph F. Connor, Corinne Bromfield, Jordan T. Gebhardt, Brian Lubbers, Hatem Kittana, Dustin Pendell, Rachel Madera, Nina Muro, Aidan Craig, Brooke Shenkenberg, Yuzhen Li, Lihua Wang, Jishu Shi   +16 more
doaj   +1 more source

Dual Lineages of Langerhans Cells Cooperate to Restore the Immune Barrier after Skin Injury

Advanced Science, EarlyView.
After skin injury, the epidermal immune barrier is rebuilt by two sources of Langerhans cells. Resident Langerhans cells first move into the wound during re‐epithelialization, guided by CXCR2 signaling. Later, recruited monocytes become long‐lived Langerhans cells.
Axel D. Schmitter‐Sánchez, Nicholas Basista, Sudhanshu Mishra, Hyeri Kim, Audrey Bench, Catherine Matte‐Martone, Min‐Soo Seo, Gun Woo Lee, Sangbum Park   +8 more
wiley   +1 more source

Notable Veterinarians of 2014, Part 2 [PDF]

, 2014
Six mid-career women veterinarians are honored as notable veterinarians who have had a positive impact on the world of animal and human health in ...
Smith, Donald F.
core   +1 more source