Results 71 to 80 of about 53,217 (242)

Purpose‐Adaptable Reinforced 3D Hyaluronic‐Acid Based Platform to Study Pathomechanisms of the Central Nervous System

Advanced Healthcare Materials, EarlyView.
Platform system to create biofabricated 3D spinal cord tissue models: Combining high resolution PCL fiber placement, a customized, hyaluronic acid‐based hydrogel, two cell types (spinal cord neurons and astrocytes) together with three distinct laminin isoforms allow the formation of functional cell–cell network interactions.
Nicoletta Murenu, Esra Tuerker, Anna‐Lena Wiessler, Jessica Faber, Ievgenii Liashenko, Jeanette Weigelt, Jörg Tessmar, Paul D. Dalton, Sibylle Jablonka, Mateo S. Andrade Mier, Carmen Villmann, Silvia Budday, Natascha Schaefer   +12 more
wiley   +1 more source

From Fiber Architecture to Functional Attachment: A Clinically Relevant, Mechanically Tunable Cardiac Patch

Advanced Materials, EarlyView.
A personalizable platform featuring a multi‐zonal cardiac patch design at clinical scale enables precise customization of fiber architecture at micro‐ and macroscale via melt electrowriting. Distinct scaffold zones support cell alignment with mechanical force transfer and epicardial attachment.
Johannes Braig, Ross Kent, Ainitze Gereka Goienetxe, Nicolás Laita, Ming Wu, Miguel Ángel Martínez, Margarida Serra, Koen Janssens, Uzuri Urtaza, Eduardo Larequi, Ilazki Anaut‐Lusar, Hilde Gillijns, Michiel Algoet, Britt van Kerkhof, Maite van der Knaap, Gerardo Cedillo‐Servin, Miguel Castilho, Alain van Mil, Joost P. G. Sluijter, Jos Malda, Piet Claus, Peter H. M. Bovendeerd, Estefanía Peña, Manuel Doblare, Wouter Oosterlinck, Stefan Janssens, Ane M. Zaldua, Olalla Iglesias‐García, Felipe Prósper, Manuel M. Mazo Vega, Jürgen Groll, Tomasz Jüngst   +31 more
wiley   +1 more source

The Challenge of Lyme Borreliosis: Knowledge, Attitudes, and Practices in France

Biology
Lyme borreliosis (LB), a zoonotic disease caused by Borrelia burgdorferi sensu lato and transmitted by Ixodes ricinus, is increasingly relevant in France, yet data on public awareness and prevention are limited.
Cynthia Philibert, Joana Ferrolho, Mark S. Gibson, Sérgio Ramalho de Sousa, Hugo Vilhena, Sofia Anastácio   +5 more
doaj   +1 more source

LEAD: Literature Enhanced Ab Initio Discovery of Nitride Dusting Layers for Enhanced Tunnel Magnetoresistance and Lower Resistance Magnetic Tunnel Junctions

Advanced Materials, EarlyView.
Magnetic tunnel junctions (MTJs) using MgO tunnel barriers face challenges of high resistance‐area product and low tunnel magnetoresistance (TMR). To discover alternative materials, Literature Enhanced Ab initio Discovery (LEAD) is developed. The LEAD‐predicted materials are theoretically evaluated, showing that MTJs with dusting of ScN or TiN on ...
Sabiq Islam, William S. Rogers, Chen‐Yu Hu, Ming‐Yuan Song, Xinyu Bao, Shehrin Sayed, Jean Anne C. Incorvia   +6 more
wiley   +1 more source

Digital Microneedles for Multiplexed Transdermal Sensing via Fluorescent QR Codes

Advanced Materials, EarlyView.
Digital fluorescent microneedles encode biochemical information in skin into scannable QR codes through threshold‐activated probes that generate binary on/off signals. By transforming analog fluorescence into discrete digital patterns, this platform enables calibration‐free, multiplexed transdermal sensing of physiologically relevant biomarkers ...
Farbod Abazar, Shahrokh Vahabi, Elena Bellotti, Martina Corsi, Irene Nocera, Paola Orlandi, Guido Bocci, Giuseppe Barillaro   +7 more
wiley   +1 more source

3D‐Printed Dynamic Heart Model With Left‐Side Anatomy and Integrated Sensor for Edge‐to‐Edge Repair and Regurgitation Reduction

Advanced Materials Technologies, EarlyView.
This work presents a fully synthetic, 3D‐printed dynamic heart model with left‐side anatomy featuring sutured mitral valve chordae tendineae analogs, embedded actuators for physiologic wall contraction, and customized flexible pressure sensors for the left ventricle.
Alejandro Guillen Obando, Hongyi Shen, Myles McGovern, Yusen Zhang, Vivien Lin, Darryl Fu, Ryan Baumwart, Kaiyan Qiu   +7 more
wiley   +1 more source

Le bien-être animal et ses ambivalences

Recherches Sociologiques et Anthropologiques
This article presents a qualitative investigation into the complex dynamics of intensive poultry farming in Italy, with a particular emphasis on the laying hen sector in the context of the Capitalocene (Moore, 2016).
Serena Finotello
doaj   +1 more source

Pre‐Encoded IFN‐I Sensitivity Exacerbates Memory T Cell Senescence in Solid Tumors

Advanced Science, EarlyView.
Type I interferon (IFN‐I) signaling promotes p21‐dependent cell cycle arrest in senescent tumor‐specific memory T cells, resulting in poor proliferative responses and solid tumor regression during cancer vaccination. Conversely, IFNα/β receptor blockade reinvigorates T cell proliferation to regress solid tumors and is more effective with increasing ...
Andrew Nguyen, Scott R Walsh, Li Deng, Lan Chen, Yonghong Wan   +4 more
wiley   +1 more source

Expandable Nanocomposite Shape‐Memory Hemostat for the Treatment of Noncompressible Hemorrhage

Advanced Science, EarlyView.
A nanocomposite‐coated shape memory foam rapidly expands, accelerates clotting, and reduces blood loss in vivo. Its fast volumetric expansion and strong procoagulant activity make it a promising hemostat for treating deep, noncompressible hemorrhage.
Saptarshi Biswas, Sarah E. Miller, Shounak Roy, Jeevika Thazhaiselvam, Samantha Foster, Manivannan Sivaperuman Kalairaj, Sasha M. George, Yava Jones‐Hall, Staci J. Horn, Fred J. Clubb, Taylor H. Ware, Duncan J. Maitland, Akhilesh K. Gaharwar   +12 more
wiley   +1 more source

Early Radiation Therapy Response Assessment Using Multi‐Scale Photoacoustic Imaging

Advanced Science, EarlyView.
Tomographic and mesoscopic photoacoustics capture intratumoural features of radioresistance and response. ABSTRACT There is a critical unmet clinical need to identify biomarkers that predict and detect radiation therapy (RT) response in cancer. Using the unique capabilities of multi‐scale photoacoustic imaging (PAI) to depict tumor oxygenation and ...
Thierry L. Lefebvre, Mariam‐Eleni Oraiopoulou, Ellie V. Bunce, Thomas R. Else, Lorna C. Wright, Monika A. Golinska, Lina Hacker, Cara Brodie, Steven Kupczak, Yi Cheng, Lisa Young, Paul W. Sweeney, Sarah E. Bohndiek   +12 more
wiley   +1 more source