A Computational Approach for Biomimetic Design of Liver‐On‐A‐Chip
Advanced Intelligent Discovery, EarlyView.A biomimetic liver‐on‐a‐chip with antiparallel perfusion was designed using COMSOL‐guided simulation to replicate hepatic acinus transport. Full‐scale modelling revealed diffusion‐dominated, length‐dependent nutrient gradients and low‐shear conditions.
Zhenxu Yang +9 more
wiley +1 more source
Structure and Function of a Multi‐Megadalton Virus‐Like Proteolytic Dodecahedron
Angewandte Chemie, EarlyView.Zuzalysin, a virulence metallopeptidase of the periodontal pathogen Porphyromonas gingivalis, is secreted as a latent, flexible ≈95‐kDa monomer. Calcium triggers cysteine‐switch activation and hierarchical assembly into pentamers, bipentamers, tripentamers, and a ≈5.6‐MDa, ≈355‐Å dodecahedron. Structures at 1.8–3.6 Å reveal a virus‐sized catalytic cage
Mariusz Madej +20 more
wiley +2 more sources
Improving access to new technologies: An experiment with Kenyan input sellers
American Journal of Agricultural Economics, EarlyView.Abstract Agrodealers play a critical role in rural economies, selling essential inputs for agricultural production, stocking new products, and providing farmers with technical advice. However, uncertainty can discourage them from stocking newer, less familiar products, limiting the availability of innovative technologies and leading to market failures ...
Sarah W. Kariuki +6 more
wiley +1 more source
Evaluation of the Utilization Pattern of Veterinary Drugs in Selected Veterinary Clinics of Mekelle City, Tigray, Ethiopia. [PDF]
Vet Med SciHagos H +3 more
europepmc +1 more source
Australian Journal of Social Issues, EarlyView.ABSTRACT People impacted by alcohol and other drugs (AOD) are supported across a range of health and social service settings, often by workers in generalist roles who may not have specialist training. Vocational education and training (VET) plays a key role in equipping AOD workers with the knowledge and skills required for practice, yet there is no ...
Kirrilly Thompson +6 more
wiley +1 more source
, 2018 Built for the School of Veterinary Medicine as a new Hospital in 1934. In the the 1950's when the Veterinary School moved all resources to west campus, this building was repurposed for use by the Civil Engineering Department.
core +1 more source
Feasibility of Using Animal Manure and Manure-Based Fertilizer as Soil Amendments: Veterinary Drugs Occurrence and Ecological Risk. [PDF]
ToxicsLi Q +6 more
europepmc +1 more source
Rapid Multi-Residue Detection Methods for Pesticides and Veterinary Drugs. [PDF]
Molecules, 2020 Jia M, E Z, Zhai F, Bing X.
europepmc +1 more source
Animal Models and Experimental Medicine, EarlyView.D‐limonene supplementation enhances testicular recovery following orchiopexy in a rat model of bilateral cryptorchidism. Treatment with D‐limonene reduces oxidative stress (↓MDA, ↑SOD, ↑GPx, ↑TAC), downregulates pro‐apoptotic proteins (↓TNF‐α, ↓BAX, ↓Caspase‐3), and upregulates anti‐apoptotic Bcl‐2 expression.
Arman Norouzi‐Ghalehbala +6 more
wiley +1 more source
Antiparasitic Veterinary Drugs-In Silico Studies of Membrane Permeability, Distribution in the Environment, Human Oral Absorption and Transport Across the Blood-Brain Barrier. [PDF]
Membranes (Basel)Sobańska AW +2 more
europepmc +1 more source