Results 91 to 100 of about 2,887,793 (388)

An Animal‐Free Patient‐Derived Tissue‐Mimetic Biochip Model of the Human Synovial Membrane for Human‐Relevant Osteoarthritis Research

Advanced Healthcare Materials, EarlyView.
Reihs et al. present the development of a humanized, animal‐free synovial membrane model for osteoarthritis. Methods include 3D biochip cultures of human‐primary OA synoviocytes with matrix and serum surrogates. Results show replication of synovial architecture and increased Yap1 expression.
Eva I. Reihs, Alexander Stoegner, Mateo G. Vasconez Martínez, Markus M. Schreiner, Melanie Cezanne, Ruth Gruebl‐Barabas, Bettina Rodriguez‐Molina, Juergen Alphonsus, Silvia Hayer, Richard Lass, Iris Gerner, Florien Jenner, Wolfgang Holnthoner, Stefan Toegel, Peter Ertl, Hans P. Kiener, Reinhard Windhager, Mario Rothbauer   +17 more
wiley   +1 more source

Nanobody‐Decorated Lipid Nanoparticles for Enhanced mRNA Delivery to Tumors In Vivo

Advanced Healthcare Materials, EarlyView.
This study presents a targeted mRNA‐LNP platform engineered with anti‐PSMA nanobodies for prostate cancer therapy. Using different in vivo models, the authors demonstrate selective uptake and mRNA delivery in PSMA+ cancer cells. However, while targeting is enhanced, mRNA delivery efficacy is limited by tissue penetration, tumor necrosis, and immune ...
Pol Escudé Martinez de Castilla, Vincenzo Verdi, Willemijn de Voogt, Mariona Estapé Sentí, Arnold C. Koekman, Julian Rietveld, Sven van Kempen, Qiangbing Yang, Juliette van Merris, Guido Jenster, Martin E. van Royen, Marcel H. Fens, Sander A. A. Kooijmans, Wytske M. van Weerden, Guillaume van Niel, Pieter Vader, Raymond M. Schiffelers   +16 more
wiley   +1 more source

Engineering Anisotropic Mechanical Properties in Large‐Scale Fabricated Cartilage Constructs Using Microfiber Reinforcement

Advanced Healthcare Materials, EarlyView.
This study presents the development of large‐scale (15 cm2) cartilage constructs with anisotropic mechanical properties using melt electrowritten (MEW) microfiber reinforced cell‐laden gelatin methacryloyl (gelMA). These constructs mimic the mechanical behavior of native cartilage, providing a suitable environment for Articular Cartilage ...
Lennard Spauwen, Alba Pueyo Moliner, Patrick van Veenendaal, Roel Custers, Jos Malda, Mylène de Ruijter   +5 more
wiley   +1 more source

Concurrent Biocompatibility and Antimicrobial Functionality of Soft Diamond‐Like Carbon Coating for Healthcare Applications

Advanced Healthcare Materials, EarlyView.
Designing an engineering material that simultaneously promotes the growth of beneficial biological cells while eliminating harmful bacteria is often challenging. However, this study presents a unique carbon coating by manufacturing design capable of achieving both functions, demonstrating strong potential for various applications, including medical ...
Abdul Wasy Zia, Alberto Tuñón‐Molina, Ioannis Anestopoulos, Miguel Martí, Iraklis‐Stavros Panagiotidis, Anam Ijaz, Ángel Serrano‐Aroca, Mihalis I. Panayiotidis, Martin Birkett   +8 more
wiley   +1 more source

Validation of the MUSIC Model of Academic Motivation Inventory: Evidence for Use With Veterinary Medicine Students

Frontiers in Veterinary Science, 2019
The MUSIC® Model of Motivation is used to help instructors select strategies that can increase students' motivation and engagement in courses. The MUSIC model is comprised of five categories of strategies titled: empowerment, usefulness, success ...
Brett D. Jones, Meghan K Byrnes, Mia W. Jones   +2 more
semanticscholar   +1 more source

Comparisons of brucellosis between human and veterinary medicine

Infection Ecology & Epidemiology, 2018
Brucellosis is the world’s most widespread zoonosis, but also ranks as one of the seven most neglected diseases, according to the World Health Organization. Additionally, it is recognized as the world’s most common laboratory-acquired infection.
N. Hull, Brant A. Schumaker
semanticscholar   +1 more source

Safety Evaluation of Repeated Application of Polymeric Microarray Patches in Miniature Pigs

Advanced Healthcare Materials, EarlyView.
This study demonstrates the safety of repeated application of three types of microarray patches (MAPs), hydrogelforming, dissolving, and implantable, over four weeks in miniature pigs. No adverse skin or systemic effects were observed, supporting the clinical potential of MAPs as safe and effective drug delivery platforms.
Qonita Kurnia Anjani, Aaron R. J. Hutton, Peter E. McKenna, Eneko Larrañeta, Ryan F. Donnelly   +4 more
wiley   +1 more source

Improvement in Clinical Symptoms and Fecal Microbiome After Fecal Microbiota Transplantation in a Dog with Inflammatory Bowel Disease

Veterinary Medicine: Research and Reports, 2019
Ayaka Niina,1 Ryoko Kibe,2 Ryohei Suzuki,1 Yunosuke Yuchi,1 Takahiro Teshima,1 Hirotaka Matsumoto,1 Yasushi Kataoka,2 Hidekazu Koyama1 1Laboratory of Veterinary Internal Medicine, School of Veterinary Medicine, Faculty of Veterinary Medicine, Nippon ...
Niina A, Kibe R, Suzuki R, Yuchi Y, Teshima T, Matsumoto H, Kataoka Y, Koyama H   +7 more
doaj  

Imaging techniques in veterinary medicine. Part II: Computed tomography, magnetic resonance imaging, nuclear medicine

European Journal of Radiology Open, 2023
Radiography and ultrasonography are the most used techniques in veterinary clinical practice, due to organizational, managerial and, mostly, economic reasons.
Adelaide Greco, Leonardo Meomartino, Giacomo Gnudi, Arturo Brunetti, Mauro Di Giancamillo   +4 more
doaj  

A study on scientific and professional life of prof. dr. hümeyra Özgen [PDF]

Eurasian Journal of Veterinary Sciences, 2020
Aim: In this study, it was aimed to reveal the national and international studies carried out veterinary science in general and animal nutrition and nutrition diseases in particular, academic and administrative duties and responsibilities, and the ...
Aşkın Yaşar, Emine Merve Danış, Esra Çelik   +2 more
doaj