Results 171 to 180 of about 2,887,793 (388)

CRISPR Screening Reveals a Novel Role for FOXH1 in Regulating Pluripotency of Porcine Embryonic Stem Cells

open access: yesAdvanced Science, EarlyView.
This study performs dual CRISPR screens in pEPSCs. Fitness screening identifies essential genes for viability, while FACS‐based screening uncovers core pluripotency factors. It highlights FOXH1 as a key regulator that maintains the stem cell state through a dual‐action mechanism: preserving pluripotency by enhancing chromatin accessibility and ...
Peng Su   +13 more
wiley   +1 more source

Conjugated Polymer Composite Flexible Wood Hydrogel‐Mediated Sequential NIR‐II Photothermal and Photodynamic Anti‐Bacteria and Macrophage Polarization for Acute Sinusitis

open access: yesAggregate, EarlyView.
This study developed a D–A–D–A conjugated polymer with NIR‐II absorption for phototherapy. The conjugated polymer nanoparticles were functionalized with hemin and embedded in a wood‐based hydrogel (LM@P/S@CP@Hemin). In MRSA‐infected rabbit sinusitis models, the NIR‐II laser treatment showed outstanding antibacterial effect, reduced inflammation, and ...
Lei He   +8 more
wiley   +1 more source

Machine Learning‐Assisted Infectious Disease Detection in Low‐Income Areas: Toward Rapid Triage of Dengue and Zika Virus Using Open‐Source Hardware

open access: yesAdvanced Intelligent Discovery, EarlyView.
This study introduces an affordable machine learning platform for simultaneous dengue and zika detection using fluorine‐doped tin oxide thin films modified with gold nanoparticles and DNA aptamers. Designed for low‐cost, hardware‐limited devices (< $25), the model achieves 95.3% accuracy and uses only 9.4 kB of RAM, demonstrating viability for resource‐
Marina Ribeiro Batistuti Sawazaki   +3 more
wiley   +1 more source

Teleoperated Magnetic Endoscopy: A Case Study and Perspective

open access: yesAdvanced Intelligent Systems, EarlyView.
This perspective highlights the recent research efforts in robotic magnetic platforms for telesurgery and their translation to clinical settings for endoscopic procedures. To demonstrate this approach, this work also introduces an in vivo gastroscopy performed in a porcine model, during which an operator in Zurich, Switzerland, successfully controls a ...
Alexandre Mesot   +8 more
wiley   +1 more source

Personalized Kirigami Strain Sensors for in vivo Applications

open access: yesAdvanced Intelligent Systems, EarlyView.
Rapid prototyping of strain sensors is demonstrated using a laser cutter that both converts carbon‐based material to strain responsible graphene and generates cuts in a kirigami‐style pattern that allows enhanced substrate flexibility. This method is used to generate wearable sensors for monitoring heart rate, limb/finger motion, and abdominal ...
Siheng Sean You   +7 more
wiley   +1 more source

Editorial: Clinical Transplantation in Veterinary Medicine [PDF]

open access: hybrid, 1987
William D. Schall   +3 more
openalex   +1 more source

A Soft‐Tip Hydraulically Steerable Catheter for Enhanced Flexibility and Safety in Vascular Interventions

open access: yesAdvanced Intelligent Systems, EarlyView.
This study introduces a hydraulically steerable catheter with a soft tip in vascular procedures. The steering soft tip achieves a minimal diameter of 2.6 mm and supports a 180° bend. Real‐time shape and position tracking, facilitated by segmentation and endpoint detection techniques, improves navigation.
Jingyi Kang   +9 more
wiley   +1 more source

Home - About - Disclaimer - Privacy