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Brucella NyxA and NyxB dimerization enhances effector function during infection
Brucella abortus thrives inside cells thanks to the translocation of effector proteins that fine‐tune cellular functions. NyxA and NyxB are two effectors that destabilize the nucleolar localization of their host target, SENP3. We show that the Nyx proteins directly interact with each other and that their dimerization is essential for their function ...
Lison Cancade‐Veyre+4 more
wiley +1 more source
The need for veterinary nursing in Nigeria [PDF]
Traditionally, nursing care has been identified as an integral part of human medicine but is not well recognised in veterinary medicine as practised in Nigeria.
Funmilayo A. Okanlawon, RN, PhD, FWACN+1 more
doaj
A Saliency-based Clustering Framework for Identifying Aberrant Predictions [PDF]
In machine learning, classification tasks serve as the cornerstone of a wide range of real-world applications. Reliable, trustworthy classification is particularly intricate in biomedical settings, where the ground truth is often inherently uncertain and relies on high degrees of human expertise for labeling.
arxiv
Made available in DSpace on 2016-03-17T20:50:28Z (GMT). No. of bitstreams: 2 812298v019i002.pdf: 20236562 bytes, checksum: e5464fd1d2875436cf50650d5785bc87 (MD5) license.txt: 4846 bytes, checksum: 927d59ba442de31571446841df3d90ca (MD5) Previous issue ...
University of Illinois. College of Veterinary Medicine
core +13 more sources
Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance
Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...
Hendrika A. Segeren+4 more
wiley +1 more source
Evaluation of the risk for the medium of the veterinary medicinal products and thew actual legislative requirements in the domain [PDF]
The Veterinary Medicine Products are authorized for marketing by the Regulating authorities, if they fulfill the scientific quality, efficiency and the safety criteria.
Ioana Diaconu,, Lollita Taban
doaj
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan+10 more
wiley +1 more source
‘One Medicine - One Health’ at the School of Veterinary Medicine of the University of Pennsylvania - the first 125 years [PDF]
The University of Pennsylvania's School of Veterinary Medicine (Penn Vet), in partnership with other veterinary schools and health professions, is positioned well to advance an international ‘One Medicine - One Health’ initiative.
Joan Hendricks, VMD, PhD+2 more
doaj
Despite the fact that health communication is a discipline developed only recently, its importance in human medicine is well recognized. However, it is less considered in veterinary medicine, even if it has the potential to improve public health because ...
Micaela Cipolla+2 more
doaj +1 more source
Comparison of surface thermal patterns of horses and donkeys in IRT images [PDF]
Infrared thermography (IRT) is a valuable diagnostic tool in equine veterinary medicine however, little is known about its application in donkeys. The aim was to find patterns in thermal images of donkeys and horses, and determine if these patterns share similarities. The study was carried out on 18 donkeys and 16 horses.
arxiv +1 more source