Results 101 to 110 of about 16,614,627 (264)

A Dual‐Membrane Biomimetic Nanoplatform Enables Triple‐Modal Therapy Against SARS‐CoV‐2 Through Viral Decoy, Inflammation Neutralizing, and Intracellular RNAi

Advanced Science, EarlyView.
[A&T]MLN is a triple‐modal nanoplatform with siRNA‐loaded LN coated with hybrid ACE2/macrophage membrane. It blocks viral entry, neutralizes IL‐6/IL‐1β/TNF‐α, and delivers siRNA to suppress viral replication. In a murine lung injury model, it attenuates inflammation, offering a multi‐pronged strategy against SARS‐CoV‐2 variants and hyperinflammation ...
Hui Li, Bohan Zhang, Chao Shang, Yi Li, Te Zhao, Shengya Liu, Dan Liu, Junwei Che, Cuiling Zhang, Pinghui Wu, Wenjie Yang, Junjie Ding, Yuhua Ran, Yanan Zhai, Haihua Xiao, Jing Gao, Xiao Li, Chunsheng Gao, Lin Li, Zhiping Li   +19 more
wiley   +1 more source

Clinicopathological and immunohistochemical description of an intrapelvic hepatoid gland carcinoma in a 14-year-old Teckel dog

, 2018
Saúde Animal Veterinary HospitalDepartment of Veterinary Clinic School of Veterinary Medicine and Animal Science São Paulo State University - UNESPCollege of Veterinary Medicine Western University of Health SciencesDepartment of Veterinary Clinic School ...
Ana Alcaraz, Jardim, Joelson, Renée Laufer-Amorim, Fonseca-Alves, Carlos E. [UNESP], Joelson Jardim, Alcaraz, Ana, Carlos E. Fonseca-Alves, Cosentino, Patrícia D. [UNESP], Kobayashi, Priscila E., Cosentino, Patrícia D., Fonseca-Alves, Carlos E., Kobayashi, Priscila E. [UNESP], Priscila E. Kobayashi, Patrícia D. Cosentino, Laufer-Amorim, Renée, Laufer-Amorim, Renée [UNESP]   +15 more
core   +1 more source

Antigen‐Detected NMR for Minimal Epitope Engineering and Structure‐Guided Selection of a NaV1.7‐Selective Nanobody

Advanced Science, EarlyView.
A minimal extracellular epitope from voltage‐gated sodium channel NaV1.7 was engineered into an isotope‐labelled antigen for antigen‐detected nuclear magnetic resonance (NMR). Together with AlphaFold2 (AF2), this enabled structure‐guided selection of R4C8, a human NaV1.7‐selective nanobody that labels fixed NaV1.7‐expressing cells and produces staining
Junyu Liu, Wanlin Chen, Ben Cristofori‐Armstrong, Theo Crawford, Kai‐En Chen, Peng Xie, Rainbow Wing Bo Chan, Yifei Zhu, Mimi Golder, Anneka Pereira Schmidt, Jennifer D. Naughton, Nicholas D. Condon, Åsa Andersson, Farhad Dehkhoda, Kirsten L. McMahon, Tabea Klasfauseweh, Ashvriya Thapa, Hue Tran, Poanna Tran, Sina Jami, Lotten Ragnarsson, Sebastian G. B. Furness, Jennifer R. Deuis, Brett M. Collins, Wai‐Hong Tham, Indira Prasadam, Irina Vetter, Mehdi Mobli   +27 more
wiley   +1 more source

Rate of Beta-Lactam Resistance and Epidemiological Features of S. Aureus-Associated Bovine Mastitis in Cross-Bred Ethiopian Cows: Systematic Review

Veterinary Medicine: Research and Reports
Melkie Dagnaw,1 Marshet Bazezew,2 Bemrew Mengistu,3 Birhan Anagaw,4 Atsede Solomon Mebratu5 1Department of Veterinary Clinical Medicine, College of Veterinary Medicine and Animal Science, University of Gondar, Gondar, Ethiopia; 2Department of ...
Dagnaw M, Bazezew M, Mengistu B, Anagaw B, Mebratu AS   +4 more
doaj  

An Injectable, Self‐Expanding Hemostatic Foam for Field‐Compatible Postpartum Hemorrhage Management

Advanced Science, EarlyView.
Postpartum hemorrhage is the leading cause of maternal death worldwide, yet many treatments are hard to use outside well‐equipped hospitals. This work introduces an easy‐to‐use device that rapidly delivers a degradable foam into the uterus. The foam stops bleeding through pressure and clotting support, offering a practical option for low‐resource ...
Charlotte Meyer, Noël Strasser, Ilakkiya Ravindrarajah, Elsa Wrenger, Kristian Ivkovic, Jan Ševčík, Sima Šarčević, Lenka Červenková, Jáchym Rosendorf, Václav Liška, Alexandre H. Anthis, Thomas Rduch, Inge K. Herrmann   +12 more
wiley   +1 more source

TNAP and PHOSPHO1 Function Synergistically to Afford Critical Control Over the Mineralization of the Postnatal Murine Skeleton

Advanced Science, EarlyView.
Biomineralization underpins skeletal development, yet its molecular control remains incompletely understood. Using a novel murine knockout model, this study reveals the essential and complementary roles of PHOSPHO1 and TNAP in postnatal skeletal development.
Lucie E. Bourne, Aikta Sharma, Scott Dillon, Jacob Keen, Soher N. Jayash, Natalie Crump, Lucinda A.E. Evans, Maya Karmali, Worachet Promruk, Claire E. Clarkin, Sonoko Narisawa, Louise Stephen, Brian L. Foster, José Luis Millán, Colin Farquharson, Katherine A. Staines   +15 more
wiley   +1 more source

Lyssavirus Nucleoprotein Induces GPAT4‐Mediated CYB5R1 Depalmitoylation to Suppress Ferroptosis and Promote Viral Replication

Advanced Science, EarlyView.
Lipid metabolism plays a vital role in viral infections. Here, we reveal that the lyssavirus N protein regulates GPAT4 to induce lipid droplet biogenesis, restricting CYB5R1 palmitoylation and reducing ferroptosis susceptibility to ultimately promote viral replication.
Jianqing Zhao, Chuan Liang, Pingping Chen, Meixin Sun, Zhen F. Fu, Ling Zhao, Ming Zhou   +6 more
wiley   +1 more source

Adult attachment, psychological stress, and quality of life: insights into Italian veterinary medicine students’ mental health

BMC Psychology
Background Veterinary medicine students face distinctive challenges, such as exposure to animal suffering and academic pressures, which can adversely affect their quality of life (QoL), particularly regarding mental health.
Anna Panzeri, Gianluca Santoro, Mattia Pezzi, Silvia Macelloni, Marta Brscic, Alessandro Schianchi, Pasquale Caponnetto, Alessandro Musetti   +7 more
doaj   +1 more source

Nonlinear Quantum Effects Drive Grotthuss Proton Conduction in Structured Electrolytes Based on Deep Eutectic Solvents

Advanced Science, EarlyView.
We demonstrate that the inverse relationship between viscosity and conductivity in structured electrolytes can be circumvented by leveraging their hydrogen bonding networks for Grotthuss proton transport. Using a mixture of imidazole and levulinic acid, we show that the existence of extended hydrogen‐bonded chains that can rapidly reorient result in ...
Benworth B. Hansen, Michael S. Chen, Giselle de A. L. e Souza, Kaylie Glynn, Alan Robledo, Emilia Pelegano‐Titmuss, Katherine Hightower, Miguel Muñoz, Rathiesh Pandian, Clemens Burda, Aikaterini Sanida, Mark Dadmun, Burcu E. Gurkan, Steve G. Greenbaum, Mark E. Tuckerman, Joshua R. Sangoro   +15 more
wiley   +1 more source

College of Veterinary Medicine Building

, 2017
One of the Buildings housing the College of Veterinary Medicine and showing part of the parking lot out front. Writing on the photo or group of photos: '' Physical description: Black and white print (photograph) 13x17.5mm; 10x12.5mm.This building was ...

core   +1 more source