Results 151 to 160 of about 4,588,201 (366)

Optimized Monothiol Thioredoxin Derivative (ORP100S) Protects In Vitro and In Vivo from Radiation and Chemotoxicity Without Promoting Tumor Proliferation

open access: yesAdvanced Science, EarlyView.
Native thioredoxin‐1 (TRX) stimulates proliferation and rescues stem cells and cancer cells from multiple stressors by suppressing p53 and inhibiting ferroptosis via GPX4/SLC7A11 upregulation mediated by enhanced KLF4 expression and p53 promoter binding.
Jian Wu   +18 more
wiley   +1 more source

Trypanosoma equiperdum in the horse : a neglected threat? [PDF]

open access: yes, 2018
Dourine is a contagious disease caused by Trypanosoma equiperdum that is transmitted directly from animal to animal during coitus. Dourine is known as an important disease in many countries, and it threatens equidae worldwide.
Ahmed, Y   +6 more
core  

Pre‐Encoded IFN‐I Sensitivity Exacerbates Memory T Cell Senescence in Solid Tumors

open access: yesAdvanced Science, EarlyView.
Type I interferon (IFN‐I) signaling promotes p21‐dependent cell cycle arrest in senescent tumor‐specific memory T cells, resulting in poor proliferative responses and solid tumor regression during cancer vaccination. Conversely, IFNα/β receptor blockade reinvigorates T cell proliferation to regress solid tumors and is more effective with increasing ...
Andrew Nguyen   +4 more
wiley   +1 more source

Role of Positron Emission Tomography in Imaging of Non-neurologic Disorders of the Head, Neck, and Teeth in Veterinary Medicine. [PDF]

open access: yes, 2019
Positron Emission Tomography (PET) is an imaging technique that provides functional information, in addition to structural information obtained with computed tomography (CT).
Culp, William TN   +2 more
core  

Deoxynivalenol Exposure Leads to Abnormal Renal Tubular Autophagy Flow

open access: yesAdvanced Science, EarlyView.
DON exposure disrupts the initiation of renal autophagy by inhibiting the formation of autophagosomes, thereby impairing mitochondrial degradation. Damaged mitochondria increase oxidative stress, reduce ferroptosis resistance, and cause lysosomal Fe2⁺ accumulation, further disrupting autophagy.
Hao Chen, Xintong Zhou, Jun Ma
wiley   +1 more source

Desk study on homeopathy in organic livestock farming: Principles, obstacles and recommendations for practice and research [PDF]

open access: yes, 2003
Organic livestock farming has its own concept of health and welfare. The approach to health can be characterised by the key words human, preventive, self-regulating and holistic (Chapter 1).
Baars, Erik   +3 more
core  

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