Results 31 to 40 of about 5,997,135 (271)

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Assessing the Impact of a Virtual Shelter Medicine Rotation on Veterinary Students' Knowledge, Skills, and Attitudes Regarding Access to Veterinary Care

Frontiers in Veterinary Science, 2021
Strong bonds commonly form between companion animals and people of all socio-demographic backgrounds, yet many pet owners face numerous barriers to accessing veterinary care for their companion animals.
Christy L. Hoffman, Terry G. Spencer, Kathleen V. Makolinski   +2 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

The Impact of a Modular Curriculum on Veterinary Students’ Quality of Life and Academic Knowledge: Proof of Concept

Medical Sciences Forum
This study examined quality of life and deep learning among 109 veterinary medicine students across three cohorts (2021–2023) in an integrated modular curriculum in Portugal.
Bárbara Gonçalves, Joana Moreira da Silva, Maria Soares, Rita Pequito, Lara Alves, Liliana Silva, Alexandre Trindade, Manuel Pequito   +7 more
doaj   +1 more source

Serological Evidence of Exposure to Leptospira spp. in Veterinary Students and Other University Students in Trinidad and Tobago

Interdisciplinary Perspectives on Infectious Diseases, 2013
The study compared the serological evidence of leptospirosis in 212 students in four schools (veterinary, dental, advanced nursing education and pharmacy) of the University of the West Indies (UWI), by testing for IgG immunoglobulins to Leptospira spp ...
Ambrose James, Kingsley Siele, Neeka Harry, Sharianne Suepaul, Alva Stewart-Johnson, Abiodun Adesiyun   +5 more
doaj   +1 more source

Veterinary student narratives of veterinary and interprofessional identity

Frontiers in Medicine
Introduction The readiness for interprofessional collaboration (IPC) is rooted in interprofessional education (IPE). IPE shapes views of IPC and socializes students into professional roles. Previous work showed differences among medical, veterinary, and dual degree Master of Public Health (MPH) students in ...
Topka, Jessica L., Hancock, Tamara S.
openaire   +2 more sources

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Veterinary Students’ Perception and Understanding of Issues Surrounding the Slaughter of Animals According to the Rules of Halal: A Survey of Students from Four English Universities

Animals, 2019
The objective of this study was to evaluate the perception and level of understanding of religious slaughter issues, and the regulations governing the process, amongst veterinary students in England. A total of 459 veterinary students in different levels,
Awal Fuseini, Andrew Grist, Toby G. Knowles   +2 more
doaj   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Susceptibility to Secondary Bacterial Infections in Growing Rabbits Exposed to Ochratoxin A and Protected or Not by Herbal Supplements

Toxins
The protective effects of the herbal feed supplements Silybum marianum, Silymarin, Withania somnifera, and Centella asiatica against ochratoxin A (OTA) toxicity were studied in 48 New Zealand White rabbits (37-day-old) during an 80-day experiment.
Kalina Zhivkova, Stoycho Stoev, Vladimir Petrov, Vesselin Ivanov   +3 more
doaj   +1 more source