Results 61 to 70 of about 2,175 (163)

Type VI secretion system : secretion by a contractile nanomachine [PDF]

, 2015
The type VI secretion systems (T6SS) are present in about a quarter of all Gram-negative bacteria. Several key components of T6SS are evolutionarily related to components of contractile nanomachines such as phages and R-type pyocins. The T6SS assembly is
Basler, Marek
core   +1 more source

Structural basis for effector transmembrane domain recognition by type VI secretion system chaperones

eLife, 2020
Type VI secretion systems (T6SSs) deliver antibacterial effector proteins between neighboring bacteria. Many effectors harbor N-terminal transmembrane domains (TMDs) implicated in effector translocation across target cell membranes.
Shehryar Ahmad, Kara K Tsang, Kartik Sachar, Dennis Quentin, Tahmid M Tashin, Nathan P Bullen, Stefan Raunser, Andrew G McArthur, Gerd Prehna, John C Whitney   +9 more
doaj   +1 more source

Expression of a Yersinia pseudotuberculosis Type VI Secretion System Is Responsive to Envelope Stresses through the OmpR Transcriptional Activator. [PDF]

PLoS ONE, 2013
The Type VI secretion system (T6SS) is a macromolecular complex widespread in Gram-negative bacteria. Although several T6SS are required for virulence towards host models, most are necessary to eliminate competitor bacteria.
Erwan Gueguen, Eric Durand, Xiang Y Zhang, Quentin d'Amalric, Laure Journet, Eric Cascales   +5 more
doaj   +1 more source

Virulence Regulation and Lifestyle Transitions: The Role of c‐di‐GMP and Two‐Component Systems in Erwinia amylovora and Their Evolutionary Context Within Enterobacterales

Molecular Plant Pathology, Volume 27, Issue 2, February 2026.
Erwinia amylovora infects apple blossoms by activating the T3SS, then spreads systemically via amylovoran‐mediated biofilms. Transitions between motile and sessile states are regulated by key two‐component systems and c‐di‐GMP. This review summarises infection biology, virulence factors, regulatory networks and evolutionary insights underlying fire ...
Dhirendra Niroula, Kalyani Bhandari, George W. Sundin, Janak R. Joshi   +3 more
wiley   +1 more source

Image_4_Redundancy and Specificity of Type VI Secretion vgrG Loci in Antibacterial Activity of Agrobacterium tumefaciens 1D1609 Strain.TIF

, 2020
Type VI secretion system (T6SS) is a contractile nanoweapon employed by many Proteobacteria to deliver effectors to kill or inhibit their competitors.
Shu-Ting Cho (811674), Chih-Feng Wu (117145), Mary Nia M. Santos (8294598), Chun-Ju Chang (184639), Erh-Min Lai (117152), Chih-Horng Kuo (63286)   +5 more
core   +1 more source

Type VI Secretion System in Pseudomonas aeruginosa: Secretion and Multimerization of VgrG Proteins [PDF]

, 2011
Pseudomonas aeruginosa is a Gram-negative bacterium causing chronic infections in cystic fibrosis patients. Such infections are associated with an active type VI secretion system (T6SS), which consists of about 15 conserved components, including the AAA+
Albesa-Jove, D., Lossi, NS, Filloux, A, Hamilton, A,, Lossi, N. S., Nadine S. Lossi, Sophie Bleves, Jones, Cerith, Lossi, Nadine S, Cerith Jones, David Albesa-Jové, Bleves, Sophie, Filloux, Alain, Hachani, A, Alain Filloux, Filloux, A., Hamilton, Alexander, Hachani, Abderrahman, Alexander Hamilton, Bleves, S, Albesa-Jové, David, Hamilton, A, Abderrahman Hachani, Jones, C, Hachani, A., Albesa-Jove, D, Lossi, Nadine S., Bleves, S.   +27 more
core   +2 more sources

Unraveling the Pathogenetic Potential and Immune Crosstalk of Yersinia spp. in Inflammatory Bowel Disease

Journal of Immunology Research, Volume 2026, Issue 1, 2026.
Yersinia enterocolitica and Yersinia pseudotuberculosis have been identified as microbiological factors in the multifactorial pathophysiology of inflammatory bowel disease (IBD). Although conventionally associated with self‐limiting gastroenteritis, Yersinia has been increasingly investigated for its potential role in IBD, particularly in genetically ...
Fattaneh Sabzehali, Verena Zerbato, Stefano Di Bella, Stefano Morabito, Mohammad Reza Zali, Abbas Yadegar   +5 more
wiley   +1 more source

Image_1_Redundancy and Specificity of Type VI Secretion vgrG Loci in Antibacterial Activity of Agrobacterium tumefaciens 1D1609 Strain.TIF

, 2020
Type VI secretion system (T6SS) is a contractile nanoweapon employed by many Proteobacteria to deliver effectors to kill or inhibit their competitors.
Shu-Ting Cho (811674), Chih-Feng Wu (117145), Mary Nia M. Santos (8294598), Chun-Ju Chang (184639), Erh-Min Lai (117152), Chih-Horng Kuo (63286)   +5 more
core   +1 more source

The Pseudomonas aeruginosa T6SS Delivers a Periplasmic Toxin that Disrupts Bacterial Cell Morphology

Cell Reports, 2019
Summary: The type VI secretion system (T6SS) is crucial in interbacterial competition and is a virulence determinant of many Gram-negative bacteria. Several T6SS effectors are covalently fused to secreted T6SS structural components such as the VgrG spike
Thomas E. Wood, Sophie A. Howard, Andreas Förster, Laura M. Nolan, Eleni Manoli, Nathan P. Bullen, Hamish C.L. Yau, Abderrahman Hachani, Richard D. Hayward, John C. Whitney, Waldemar Vollmer, Paul S. Freemont, Alain Filloux   +12 more
doaj   +1 more source

Phenotypical and Genomic Characterization of the Mollusk Pathogen Francisella halioticida

MicrobiologyOpen, Volume 14, Issue 6, December 2025.
Phenotypic and genetic characterization of French isolates of Francisella halioticida and comparison with Canadian and Japanese strains. The study revealed similarities between FR22s and previous isolates but distinct differences with FR21. A major finding is the absence of the Francisella pathogenicity island in the less virulent isolate, FR22b ...
Hélène Bouras, Yann Quesnelle, Suzanne Trancart, Didier Goux, Jean‐Louis Blin, Manuel Savary, Maryline Houssin, Céline Zatylny‐Gaudin   +7 more
wiley   +1 more source