Results 61 to 70 of about 52,478 (246)
ARQ, 2003 El programa de estos edificios industriales ha incorporado un espacio de escala menor pero de un uso intenso y expuesto: la sala de degustaciones, donde trabaja el enólogo y se recibe a los visitantes.
Paulina Courard
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Confabulaciones, 2020 En este artículo procuro trazar un recorrido sobre aquellos núcleos e ideologemas que articulan el trabajo intelectual de David Viñas, como crítico y ensayista, como narrador de la historia nacional y de sus aristas más violentas.
Nancy Fernández
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Advanced Science, EarlyView.WTAP drives cartilage regeneration by activating an LRP1‐dependent lipid metabolic program in macrophages, enhancing IL‐10 and TGF‐β secretion to promote chondrogenic differentiation. Leveraging this mechanism, virtual screening identifies LRP1‐targeting compounds that effectively stimulate cartilage repair, highlighting a druggable epigenetic ...
Chenyan Huang +6 more
wiley +1 more source
Advanced Science, EarlyView.Complex hydride anion substitution in argyrodite electrolytes has attracted attention for improving interfacial stability, yet the influence of these anions at Li metal interfaces remains unclear. This work shows that electrochemically formed BH4−‐derived interphases enable stable high‐current full‐cell cycling.
Sangho Lee +13 more
wiley +1 more source
Perilipin‐2‐Anchored Lipid Droplet‐Targeting Phototheranostics
Angewandte Chemie, EarlyView.This study reports two NIR theranostic dyes, C‐BDP‐OH and C‐BDP‐OMe. C‐BDP‐OMe targets lipid droplets via a dual‐anchoring mechanism with PLIN2, enabling wash‐free tumor imaging. With 62.6% photothermal conversion efficiency, it achieves tumor ablation by downregulating PLIN2, disrupting LD‐mitochondria crosstalk, and triggering apoptosis and ...
Lipeng Zhang +9 more
wiley +2 more sources
Advanced Science, EarlyView.SMarT‐Diff introduces a multi‐objective generative paradigm that integrates scaffold hopping with structure‐aware scoring to enable controlled exploration beyond the training distribution. The framework consistently balances drug‐likeness, synthesizes accessibility and bioactivity, yielding chemically diverse candidates with enhanced properties.
Yuwei Yang +8 more
wiley +1 more source
Application of Pulsed Electric Fields for Obtaining Antioxidant Extracts from Fish Residues
Antioxidants, 2020 Fish processing has serious economic and environmental costs in the food supply chain. It is necessary to find new ways to convert fish residue to added-value products, especially for main aquaculture species. In this study, a pulsed electric field (PEF)
Daniel Franco +6 more
doaj +1 more source
Ferritinophagy Rewires Carnitine‐Dependent Lipid Metabolism to Inhibit PRRSV and IAV Replication
Advanced Science, EarlyView.NCOA4‐mediated ferritinophagy reprograms carnitine metabolism by disrupting Fe‐S cluster biogenesis, thereby establishing an iron‐lipid axis that suppresses various viruses, including PRRSV and IAV. However, viruses counteract this mechanism by degrading NCOA4.
Kaifeng Guan +7 more
wiley +1 more source
A Non‐Covalent [4Fe–4S]/[2Fe] Interface in HydF Guides [FeFe]‐Hydrogenase Maturation
Angewandte Chemie, EarlyView.Bridged or not? 57Fe NRVS reveals a non‐covalent, electronically coupled interaction between the HydF [4Fe–4S] cluster and the [2Fe] precursor. Boltz‐2 structure predictions suggest that the cubane organizes lipoate‐dependent Hmet chemistry, positioning intermediates for assembly of the CH2–NH–CH2 bridge during H‐cluster biosynthesis.
Giorgio Caserta +6 more
wiley +2 more sources
Factores de riesgo de sepsis en menores de un año
Medisan, 2013 Se realizó un estudio analítico de casos y controles, a fin de identificar algunos factores de riesgo en menores de un año ingresados por sepsis en la Unidad de Cuidados Intensivos Pediátricos del Hospital General Docente "Juan B.
Elio Goide Linares +4 more
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