Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Self-Help and the London Mechanics' Institution - Birkbeck after (George) Birkbeck [PDF]
The London Mechanics’ Institute is notable not only for its place in the history of the Mechanics’ Institute movement, but also for the conflicts which surrounded its formation in 1823.
Clarke, Richard
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Adaptive Optics for Extremely Large Telescopes
Adaptive Optics has become a key technology for the largest ground-based telescopes currently under or close to begin of construction. Adaptive optics is an indispensable component and has basically only one task, that is to operate the telescope at its ...
Hippler, Stefan
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An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino +7 more
wiley +1 more source
Considerations on the physical and mechanical properties of lime-stabilized rammed earth walls and their evaluation by ultrasonic pulse velocity testing [PDF]
This study examines the influence of moulding moisture content on the compressive strength, dry density and porosity of a rammed earth wall, using ultrasound as a complementary technique.
Alejandre Sánchez, Francisco Javier +4 more
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By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
The Texas Supreme Court and Oil and Gas Jurisprudence: What Hath Wagner & Brown v. Sheppard Wrought? [PDF]
So now the question for players in the oil patch is: What hath Wagner & Brown v. Sheppard wrought? This article discusses that question, assesses the effects of the Sheppard decision on oil and gas jurisprudence, and provides suggestions for addressing ...
Laura H. Burney
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Hematopoietic (stem) cells—The elixir of life?
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Compost and digestate: sustainability, benefits, impacts for the environment and for plant production [PDF]
This proceedings volume contains the papers presented at the CODIS 2008 congress held on 27 - 29 February 2008 in Solothurn (Switzerland).The composting and digestion of biogenic waste materials and the subsequent application of compost and digestate to ...
Fuchs, Jacques G. +3 more
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