Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
wiley +1 more source
A Review of Plant Selenium-Enriched Proteins/Peptides: Extraction, Detection, Bioavailability, and Effects of Processing. [PDF]
Xiong Y +8 more
europepmc +1 more source
The role and implications of mammalian cellular circadian entrainment
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Functional Connectivity Increases in Response to High-Definition Transcranial Direct Current Stimulation in Patients with Chronic Disorder of Consciousness. [PDF]
Han J +8 more
europepmc +1 more source
An improved prediction model for COD measurements using UV-Vis spectroscopy
We have proposed and developed an improved online COD prediction measurement. The work includes designing the structure and workflow of an online automatic detection module, and proposing an improved noise removal method and a COD detection network.
Li Guan, Yijun Zhou, Sen Yang
openaire +2 more sources
A study of some aspects of growth and reproduction in two inbred lines of mice and their crosses : a thesis presented in partial fulfilment of the requirements for the degree of Master of Agricultural Science in Massey University of Manawatu [PDF]
The mating of closely related individuals is generally believed to result in inferior offspring. Recognition of this danger has been suggested as the reason for evolution of human social customs.
Lawson, R A S
core
Molecular bases of circadian magnesium rhythms across eukaryotes
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
A bankok által alkalmazott működési kockázatkezelési módszerek és az intézményméret viszonya [PDF]
A működési kockázat tudatos kezelése a 2007–2008-ban bevezetett Bázel II-es kockázatkezelési és tőkeallokációs keretrendszer fontos újdonsága. A szabályozás lehetőséget ad egyszerűbb és fejlettebb módszerek alkalmazására.
Homolya, Dániel
core
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source

