Results 231 to 240 of about 13,318,066 (293)

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

[VI. Improvement of combined modality therapy for pancreas cancer].

open access: yes[VI. Improvement of combined modality therapy for pancreas cancer].
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Solution properties of polymethacrylate VI improvers

Lubrication Science, 1988
AbstractThis paper reports an attempt to determine the applicability of Kraemer and Huggins equations of dilute solutions, to the VI improver polymethacrylate. The equations are used to provide an estimate of the intrinsic viscosity of the polymer in a given solvent at a given temperature.
C. Neveu, F. Huby
openaire   +2 more sources

Solution Viscosity Studies On OCP VI Improvers In Oils

SAE Technical Paper Series, 1989
<div class="htmlview paragraph">MRV, CCS, and solution viscosity data were obtained on oil solutions of several OCP VI improvers with ethylene to propylene molar ratios of 60:40 to 80:20. High amounts of ethylene accompanied by some crystalline structure resulted in lower MRV and CCS values.
Maria m. Kapuscinski   +2 more
openaire   +2 more sources

Improved Synthesis of Mirtazapine (VI).

ChemInform, 2007
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
D. V. N. Srinivasa Rao   +5 more
openaire   +1 more source

Role of emerging markets vis-à-vis frontier markets in improving portfolio diversification benefits

International Review of Economics & Finance, 2022
Abstract The study examines the value addition provided by frontier markets vis-a-vis emerging markets in improving the diversification benefits of an international portfolio. The analysis is performed for Asia-Pacific and Europe. It also surveys international investors to corroborate the empirical findings.
Nisha Mary Thomas   +3 more
openaire   +1 more source

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