Results 41 to 50 of about 1,568 (176)

Cardiac‐specific Kv1.1 deficiency alters cardiomyocyte electrophysiology without modifying overall cardiac function or arrhythmia susceptibility

open access: yesExperimental Physiology, Volume 111, Issue 3, Page 1120-1133, 1 March 2026.
Abstract The leading cause of epilepsy‐related mortality is sudden unexpected death in epilepsy (SUDEP), resulting from seizure‐induced cardiorespiratory arrest by mechanisms that remain unresolved. Mutations in ion channel genes expressed in both brain and heart represent SUDEP risk factors because they can disrupt neural and cardiac rhythms ...
Kelsey Halvorson   +11 more
wiley   +1 more source

Investigating the Epidemiology of Haemonchus contortus, Using Traditional Faecal Diagnostics Supported by Deep‐Amplicon Sequencing, in an Outbreak of Haemonchosis in a Scottish Pedigree Sheep Flock

open access: yesCase Reports in Veterinary Medicine, Volume 2026, Issue 1, 2026.
This case report describes an investigation of an outbreak of haemonchosis in a Scottish pedigree sheep flock. The case occurred in a small lowland flock of pedigree Spotted Dutch sheep (n = 16) grazing pasture previously grazed by alpacas and horses.
A. Luque Castro   +8 more
wiley   +1 more source

Classificação de indivíduos segundo comportamento individual relativo a viagens a partir de dados em painel obtidos por smartphones

open access: yesTransportes, 2019
A caracterização comportamental relativa a viagens é uma questão importante nas análises baseadas em atividades e, comumente, é a variável dependente nos modelos de estimativa de demanda por transportes. A classificação individual, segundo comportamentos
Lucas Assirati, Cira Souza Pitombo
doaj   +3 more sources

DESVENDANDO CAMINHOS DO TURISMO DE AVENTURA NO BRASIL

open access: yesRevista Iberoamericana de Turismo, 2011
O turismo de aventura fundamenta-se no lazer de natureza, na aventura e risco que turistas desejam experimentar exigindo cuidados especiais. Diferencia-se dos esportes radicais ou ecoesportes realizados por profissionais.
Luzia Neide Menezes Teixeira Coriolano   +1 more
doaj  

El viaje y sus huellas

open access: yesRevista Alembra
A literatura de viagens, origem de muitos mitos fundadores discursivos sobre inúmeras nações ao redor do globo, tem sua relevância científica alicerçada sobre as bases das identidades forjadas através dos milênios.
Rossemildo da Silva Santos
doaj   +1 more source

The seasonality of gastrointestinal nematode species abundance (excluding Nematodirus) in sheep of different classes across New Zealand

open access: yesNew Zealand Journal of Agricultural Research, Volume 68, Issue 7, Page 2436-2455, December 2025.
ABSTRACT A survey on nine farms across New Zealand assessed the seasonality and species composition of gastrointestinal nematodes in three sheep classes: lambs (<1 year), 2‐tooth ewes (1–2 years), and mixed age ewes (>2 years). Monthly faecal samples from each class underwent faecal egg counting and deep amplicon sequencing of cultured third‐stage ...
Tania Waghorn   +7 more
wiley   +1 more source

Amazonas, Marañon, Ucayali: olhares, experiências, escritos

open access: yesArtCultura
A Amazônia ganha relevo quando se visualiza o território que veio a constituir a América. Foi explorada ao longo do tempo, tanto pela curiosidade e cobiça, como pelo desejo de ampliação do conhecimento do mundo.
Márcia Regina Capelari Naxara
doaj   +1 more source

Unique Role of Proximal Tubule Dipeptidyl Peptidase 4 on Blood Pressure, Renal Sodium Handling, and Na+/H+ Exchanger Isoform 3 Phosphorylation

open access: yesActa Physiologica, Volume 241, Issue 12, December 2025.
ABSTRACT Background Dipeptidyl peptidase 4 (DPP4) is a transmembrane serine exopeptidase highly expressed in the proximal tubule (PT). While its enzymatic role is well characterized, its non‐enzymatic functions remain unclear. DPP4 physically associates with the Na+/H+ exchanger isoform 3 (NHE3), and DPP4 inhibitors promote natriuresis; however, the ...
Flavia L. Martins   +4 more
wiley   +1 more source

Inhibition of Hippo Signaling Through Ablation of Lats1 and Lats2 Protects Against Cognitive Decline in 5xFAD Mice via Increasing Neuronal Resilience Against Ferroptosis

open access: yesAging Cell, Volume 24, Issue 11, November 2025.
5xFAD mice exhibited abnormal activation of Hippo signaling. Ablation of Lats1 and Lats2 in 5xFAD mice to inhibit Hippo signaling resulted in augmented cognition and ameliorated neurodegeneration, which were mediated by increased neuronal resilience against ferroptosis.
Robert C. Evans   +7 more
wiley   +1 more source

ZNHIT3 Regulates Translation to Ensure Cell Lineage Differentiation in Mouse Preimplantation Development

open access: yesAdvanced Science, Volume 12, Issue 21, June 5, 2025.
Box C/D snoRNP complex regulates protein translation. This study identifies ZNHIT3 as a key component of the complex and ensures normal protein expression, including transcription factors orchestrating cell fate commitment, during early mouse embryogenesis.
Guanghui Yang, Qiliang Xin, Jurrien Dean
wiley   +1 more source

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