Results 91 to 100 of about 480,558 (286)
Does Epistemic Humility Threaten Religious Beliefs? [PDF]
, 2018 In a fallen world fraught with evidence against religious beliefs, it is tempting to think that, on the assumption that those beliefs are true, the best way to protect them is to hold them dogmatically.
Dormandy, Katherine
core
Advanced Science, EarlyView.This study revealed how the osteoblastic microenvironment determines the fate of cancer cells disseminated in bone, with a focus on whether they colonize, reside in quiescence, or reactivate from dormancy. Targeting integrin signaling may offer promising strategies for preventing quiescent cancer cells reactivation and bone colonization.
Hong‐Li Wang +7 more
wiley +1 more source
L’orgie électronique. Vices et vertus du paysage Facebook
Comunicação e Sociedade, 2012 Facebook est un royaume où ce sont les sens qui pensent et non la pensée qui dirige la sensibilité. Au coeur de ce système se développe une éthique alimentée par des ivresses ludiques, des pulsions oniriques et des adhésions esthétiques, pouvant faire ...
Vincenzo Susca
doaj +1 more source
HIDING BEHIND THE CLOUDS: EFFICIENT, PRIVACY-PRESERVING QUERIES VIA CLOUD PROXIES [PDF]
, 2014 This project proposes PriView, a privacy-preserving technique for querying third-party ser- vices from mobile devices. Classical private information retrieval (PIR) schemes are diffi- cult to deploy and use, since they require the target service to be ...
Gaur, Surabhi
core +1 more source
Educating through Exemplars: Alternative Paths to Virtue [PDF]
, 2017 This paper confronts Zagzebski’s exemplarism with the intertwined debates over the conditions of exemplarity and the unity-disunity of the virtues, to show the advantages of a pluralistic exemplar-based approach to moral education (PEBAME).
Annas J +21 more
core +2 more sources
Advanced Science, EarlyView.Lipid overload suppresses SREBF2‐mediated FNTB expression, leading to defective Lamin A maturation and nuclear envelope instability. This nuclear catastrophe triggers a pro‐fibrotic senescence program in cardiomyocytes. Notably, restoring nuclear integrity via AAV9‐based gene therapy effectively attenuates cardiac remodeling, identifying the ...
Yuxiao Chen +16 more
wiley +1 more source
Advanced Science, EarlyView.This research identified cardiac amyloid pathology, neurotrophic factor depletion, and reduced myocardial nerve function in a transgenic model of cerebral amyloidosis (Tg2576), Aβ‐challenged cardiomyocytes, and in human AD heart tissue. These findings carry significant diagnostic and therapeutic implications, emphasizing the role of neuro‐signaling ...
Andrea Elia +6 more
wiley +1 more source
The Virtue of Gratitude and Its Associated Vices [PDF]
Gratitude, the proper or fitting response to benevolence, has often been conceptualized as a virtue—a temporally stable disposition to perceive, think, feel, and act in certain characteristic ways in certain situations.
Manela, Tony
core
A virtue epistemology of the Internet: Search engines, intellectual virtues and education [PDF]
, 2017 This paper applies a virtue epistemology approach to using the Internet, as to improve our information-seeking behaviours. Virtue epistemology focusses on the cognitive character of agents and is less concerned with the nature of truth and epistemic ...
Heersmink, Richard
core +1 more source
Advanced Science, EarlyView.This study reveals that m6A regulators cooperatively upregulate BGN in melanoma, promoting malignancy. Within the tumor microenvironment, CAFs show highest BGN expression. The BGN/MDK axis mediates cancer‐stroma crosstalk, driving normal fibroblast (NF) activation and enhancing the pro‐tumor effect of CAFs, highlighting a promising therapeutic target ...
Hao‐ze Shi +16 more
wiley +1 more source