Results 121 to 130 of about 480,558 (286)
Advanced Science, EarlyView.Fibronectin regulates the extracellular matrix (ECM)–myofibroblast cycle through three key steps: (1) its secretion and assembly by myofibroblasts (inhibited by pUR4); (2) collagen deposition along its scaffold (inhibited by R1R2); and (3) integrin α5β1‐mediated mechanotransduction (inhibited by ATN161).
Wenlong Ma +10 more
wiley +1 more source
The Virtues and Vices of a Judge: An Aristotelian Guide to Judicial Selection [PDF]
, 1988 A core insight of the legal realists was that many disputes are indeterminate. For example, in many appellate adjudications, respectable legal arguments can be made for both sides of the dispute. A contemporary reaction to the realist insight by critical
Solum, Lawrence B.
core +1 more source
Microglial GPR35 Ameliorates Epileptogenesis and Neuroinflammation via PDGFA Domain 2 Signaling
Advanced Science, EarlyView.Activation of microglial G protein–coupled receptor 35 (GPR35) by L‐kynurenic acid (L‐Kyna) initiates a platelet‐derived growth factor A (PDGFA)–dependent phosphoinositide 3‐kinase–protein kinase B (PI3K–AKT) signaling cascade that dampens hippocampal neuroinflammation, thereby restraining epileptogenesis, lowering seizure susceptibility, and ...
Qi Wang +17 more
wiley +1 more source
Virtues Suffice for Argument Evaluation
Informal LogicThe virtues and vices of argument are now an established part of argumentation theory. They have helped direct attention to hitherto neglected aspects of how we argue.
Andrew Aberdein
doaj +1 more source
Mineralized Cryogel/Hydrogel Constructs to Recapitulate Early Breast Cancer Bone Metastasis In Vitro
Advanced Science, EarlyView.A new biphasic in vitro cryogel/hydrogel model of early breast cancer bone metastasis provides precise control over microenvironmental cues and microscopic access to the spatiotemporal cancer cell distribution. Deposited bone‐like mineral is observed to strongly impede the effects of biomolecular signals, as evidenced by both colonization profiles and ...
Jana Sievers‐Liebschner +8 more
wiley +1 more source
Costume Design for \u3cem\u3eVolpone\u3c/em\u3e by Ben Jonson [PDF]
, 2017 This poster presentation provides information about my final design for the Linfield College Theatre Program’s Costume Design course taught by Laurel Peterson during the 2016 fall semester.
Olson, Rosalie S.
core +1 more source
Advanced Science, EarlyView.Upon NIR irradiation at 808 nm, the activity of TRPV4 was inhibited by M2M@BPSC, which led to reduced calcium influx, mitochondrial protection, and, importantly, the transcriptional activation of the STAT6‐EGR2 pathway. The improved macrophage function indirectly readjusts the equilibrium between C‐ECM and F‐ECM to reconstruct a suitable ...
Chenqi Yu +11 more
wiley +1 more source
L'analyse économique des vices du consentement : une nouvelle vision d'une théorie classique
, 2008 Le concept économique d'information pourrait être réapproprié par le droit afin de lever certaines contradictions dans la théorie des vices du ...
Rouvière, Frédéric
core +1 more source
Macrophage Extracellular Traps in Immunity and Cancer
Advanced Science, EarlyView.As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li +5 more
wiley +1 more source