Results 121 to 130 of about 66,264 (314)

The relationship between teachers’ critical thinking, experiences of victimization in educational institutions, and psychological well-being

Frontiers in Psychology
IntroductionTeacher victimization is a growing concern with well-documented implications for educators’ psychological well-being. However, less is known about how such experiences relate not only to emotional outcomes but also to critical thinking.
Rugile Bitinaite, Aiste Dirzyte, Odeta Merfeldaite, Jolanta Pivoriene, Valdone Indrasiene, Violeta Jegeleviciene, Romas Prakapas, Asta Railiene, Daiva Penkauskienė, Justinas Sadauskas, Marina Gusauskiene   +10 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

A longitudinal study on the relationships between maternal parenting style, children’s victimization, and self-esteem

Frontiers in Psychiatry
BackgroundPrevious studies have established that parenting style and self-esteem affect children’s risk of victimization. This study further investigates the longitudinal mechanisms by which maternal warmth and rejection, along with self-esteem ...
Dandan Cheng, Cui Wang, Minghui Xiong, Ran Mo, Yuxuan Nie, Junsheng Liu   +5 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

More serious cases of victimization and offending

For almost the first time working with ISRD data, this chapter explores the seriousness of criminal victimization and offending. Seriousness is examined first as an attribute of individuals, looking at repeat victims and repeat offenders, and second as ...
Birkbeck, Christopher, Kivivuori, Janne, Rezende Bazon, Marina, Rodríguez, Juan Antonio, Kaakinen, Markus, Manzoni, Patrik   +5 more
core   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Repeat and near-repeat victimization in Campinas, Brazil: new explanations from the Global South

, 2017
Criminological research has consistently found that crime clusters in both space and time. A subset of this research has investigated repeat victimization (same victim re-victimized within a short period of time) and near-repeat victimization (places ...
Andresen, Martin A, Silas Nogueira de Melo, Lindon Fonseca Matias, Matias, Lindon Fonseca, Martin A. Andresen, de Melo, Silas Nogueira   +5 more
core   +1 more source