Results 61 to 70 of about 66,264 (314)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Extended reality (XR) in psychosocial and forensic interventions for child and adolescent sexual abuse: a systematic review of current applications and future directions

Frontiers in Psychology
The integration of extended reality (XR) technologies—virtual (VR) and augmented (AR)—into child sexual abuse (CSA) interventions has grown over the past decade.
Varinia Leiva, Noemí Pereda, Noemí Pereda, Nicolás Cenzano   +3 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Factors leading to cyber victimization

, 2019
The proliferation of digital technologies in the past years has seen the adaptation of lifestyles merge between the online and offline domain. The introduction of Information and Communication Technologies (ICTs) has provided numerous beneficial ...
Oonagh L. Steer, Macaulay, Peter, Steer, Oonagh L., Betts, Lucy R., Lucy R. Betts, Peter J.R. Macaulay, Macaulay, Peter J.R.   +6 more
core   +1 more source

Dating violence (DV): a systematic meta-analysis review

Anales de Psicologia, 2020
This study summarizes the results of meta-analyses about risk and protective factors related to dating violence (DV). Fifteen studies were included from 1997 to 2018, N = 1784018. The results were classified according to ecological theory.
Marcela Gracia-Leiva, Alicia Puente-Martínez, Silvia Ubillos-Landa, Darío Páez-Rovira   +3 more
doaj   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

The Importance of Developmental Science for Studies in Bullying and Victimization

, 2012
Research on bullying and victimization, especially in school settings, has become an important area of developmental research, with strong practical implications. In this article we overview some considerations from neuropsychology, quantitative genetics,
Smith, Peter K., Jones, Alice P.
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Cyber-victimization—influence of parental rules and impact on mental health among Indian adolescents

Frontiers in Psychology
IntroductionIn the contemporary digital age, cyberspace offers numerous benefits but also presents significant risks, including cyber-victimization. Adolescents, as frequent internet users, are particularly vulnerable to such experiences.
Rameshbabu Tamarana, Mansi Mathur, Varsha Madhusudan, P. Annapurna Kiranmai   +3 more
doaj   +1 more source