Results 31 to 40 of about 200 (129)
ABSTRACT Background Ventilator‐induced diaphragmatic dysfunction (VIDD) is a major complication in critically ill patients. Prolonged mechanical ventilation (MV) triggers diaphragmatic fibrotic remodelling, but the underlying mechanisms remain unclear. This study investigated the role of the mechanosensitive channel Piezo1 in this process.
Dan Xie +9 more
wiley +1 more source
Abstract figure legend 2H2O labelling was used to examine muscle protein fractional synthesis rates (FSR) in an intensive care unit (ICU) model and non‐anaesthetized control rats, and to compare the effects of a Janus kinase (JAK)/STAT inhibitor on protein FSR in the ICU model.
William J. Evans +9 more
wiley +1 more source
Role of the Chest Wall in Newborn Respiratory Function at Birth
At birth, liquid is cleared from the airways into lung tissue during lung aeration, causing the lungs to swell, which in turn causes the chest wall to expand. As the newborn chest wall is highly compliant, it can easily expand, but its high compliance reduces breathing efficiency after birth.
C. Diedericks +8 more
wiley +1 more source
Diaphragm Function in Very Preterm Infants at 36 Weeks' Postmenstrual Age
ABSTRACT Objectives Understand how bronchopulmonary dysplasia (BPD) and antenatal and postnatal factors influence diaphragmatic functional effectiveness in very preterm infants. Working Hypothesis Diaphragmatic functional effectiveness during spontaneous breathing is impaired in infants with BPD.
Benjamin Stoecklin +4 more
wiley +1 more source
New perspectives on the physiological basis of muscle loss
Experimental Physiology, EarlyView.
Alistair J. Monteyne, Marlou L. Dirks
wiley +1 more source
Abstract Dual inhibition of sodium glucose cotransporters 1 and 2 (SGLT1/SGLT2) by sotagliflozin protects the kidney and heart in patients with type 2 diabetes mellitus (T2DM) and chronic kidney disease (CKD). To gain mechanistic insights, the current study aimed to establish a murine model of hypertensive CKD that shows cardio‐renal protection by ...
Helen Goodluck +6 more
wiley +1 more source
Chaperone Proteins: The Rising Players in Muscle Atrophy
ABSTRACT Despite significant progress in understanding the molecular aetiology of muscle atrophy, there is still a great need for new targets and drugs capable of counteracting muscle wasting. The role of an impaired proteostasis as the underlying causal mechanism of muscle atrophy is a well‐established concept. From the earliest work on muscle atrophy
Davide Acquarone +3 more
wiley +1 more source
This chapter introduces readers to the practice of creating fan music videos, commonly referred to as vids or fanvids. Fans combine preexisting material from films or television with music in order to refocus the original source material for various ...
Nina Treadwell
core +1 more source
“A Decade of [in]Transition: Reflecting on Past Challenges and Future Possibilities” describes the editorial experience of the award-winning, peer-reviewed journal [in]Transition on the occasion of its ten-year anniversary.
Kevin L. Ferguson, Drew Morton
doaj +1 more source
Avhopp vid internetbaserad KBT behandling vid depression
I denna studie har avhopp undersökts i relation till två internetbaserade kognitiva beteendeterapi-behandlingar för depression baserat på data från ett forskningsprojekt kallat Konrad. Behandlingarna skilde sig åt i den textmängd som patienten fick läsa under behandlingens gång men var i övrigt likvärdiga.
Roos-Pehrsson, Viktor +1 more
openaire +1 more source

