Results 31 to 40 of about 131,212 (218)

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Correlation Between Pain Intensity and Quality of Recovery After Video-Assisted Thoracic Surgery for Lung Cancer Resection

Journal of Pain Research, 2023
Soo-Hyuk Yoon,1,* Jinyoung Bae,2,* Susie Yoon,1,3 Kwon Joong Na,4,5 Ho-Jin Lee1,3 1Department of Anesthesiology and Pain Medicine, Seoul National University Hospital, Seoul, Republic of Korea; 2Department of Anesthesiology and Pain Medicine, Ajou
Yoon SH, Bae J, Yoon S, Na KJ, Lee HJ
doaj  

A nationwide student survey on biochemistry learning resources in Italy

FEBS Open Bio, EarlyView.
We conducted a survey among Italian university students to investigate their preferred study materials for biochemistry. We then analyzed the collected data to identify these materials. This information may be valuable to the Biochemistry educational community. The graphical abstract was created with Claude (Opus 5.5; Anthropic, 2026).
Anna Marabotti, Ivano Eberini, Maria Luisa Genova, Francesca Mensitieri, Francesco Malatesta   +4 more
wiley   +1 more source

Disruption of Radiological Surveillance Following a Global Health Crisis in Resected Lung Cancer

Thoracic Cancer
Objectives Radiological surveillance after curative‐intent lung cancer resection is essential for early detection of recurrence and second primary tumors. Large‐scale health emergencies can compromise oncologic follow‐up. This study quantifies the impact
Álvaro Fuentes‐Martín, Néstor J. Martínez‐Hernández, Raul Embun, María Fé Muñoz Moreno, Ángel Cilleruelo Ramos, the Spanish Group of Video‐assisted Thoracic Surgery (GEVATS)   +5 more
doaj   +1 more source

Impact of video-assisted thoracoscopic lobectomy versus open lobectomy for lung cancer on recovery assessed using self-reported physical function: VIOLET RCT

Health Technology Assessment, 2022
Background: Lung cancer is the leading cause of cancer death. Surgery remains the main method of managing early-stage disease. Minimal-access video-assisted thoracoscopic surgery results in less tissue trauma than open surgery; however, it is not known ...
Eric Lim, Rosie A Harris, Holly E McKeon, Timothy JP Batchelor, Joel Dunning, Michael Shackcloth, Vladimir Anikin, Babu Naidu, Elizabeth Belcher, Mahmoud Loubani, Vipin Zamvar, Lucy Dabner, Timothy Brush, Elizabeth A Stokes, Sarah Wordsworth, Sangeetha Paramasivan, Alba Realpe, Daisy Elliott, Jane Blazeby, Chris A Rogers   +19 more
doaj   +1 more source

Screening Routine Clinical Notes for Epilepsy Surgery Candidates Using Large Language Models

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy surgery is severely underutilized despite proven efficacy, with substantial under‐referral of eligible patients in routine clinical practice. This study evaluated the potential role of large language models (LLMs) as decision‐support tools for screening unstructured clinical notes to identify epilepsy surgery candidates and ...
Uriel Fennig, Nadav Amir, Maya Schiller, Roni Loebenstein, Johnatan Nissan, Marina Boxer, Shany Guly Gofrit, Gal Goshen, Sándor Beniczky, Nicola Maggio   +9 more
wiley   +1 more source

Association between perioperative cholesterol level and analgesia after video-assisted thoracoscopic surgery [PDF]

Korean Journal of Anesthesiology, 2019
Background Cholesterol plays an important role in the action of opioid analgesics, but its association with postoperative pain has not been clarified. Our study examined the association of pre- and postoperative total serum cholesterol (TSC), and change ...
Tak Kyu Oh, Kwanmien Kim, Sanghoon Jheon, Hei-jin Lee, Sang-Hwan Do   +4 more
doaj   +1 more source

Evaluation of Digital Technologies for Home‐Based Assessment in People With Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller, Vanessa Vallejo, Mónica Povedano Panadés, Orla Hardiman, Véronique Danel‐Brunaud, Senda Ajroud‐Driss, Philippe Couratier, Jeremy Shefner, Anna Gokey, Mike DiCesare, Erin Lennox, Jens Praestgaard, Lucie Brujin, Peggy Allred, Ram Miller   +14 more
wiley   +1 more source

Comparison of the standard McCoy laryngoscope and video-assisted McCoy laryngoscope for laryngoscopy and intubation in patients with simulated difficult airway

Indian Journal of Anaesthesia
Background and Aims: Video laryngoscopes provide better visualisation of glottis and easier tracheal intubation as compared to the McCoy laryngoscope. However, cost constraints limit their use. The video-assisted McCoy laryngoscope provides the advantage
Teena Bansal, Mamta Jain, Chetan Kumar, Anish Kumar Singh, Jatin Lal, Suresh Singhal   +5 more
doaj   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source