Results 71 to 80 of about 558,335 (292)

Evaluation of Digital Technologies for Home‐Based Assessment in People With Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller   +14 more
wiley   +1 more source

Towards Hybrid Cloud-assisted Crowdsourced Live Streaming: Measurement and Analysis

open access: yes, 2016
Crowdsourced Live Streaming (CLS), most notably Twitch.tv, has seen explosive growth in its popularity in the past few years. In such systems, any user can lively broadcast video content of interest to others, e.g., from a game player to many online ...
Liu, Jiangchuan   +2 more
core   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit   +11 more
wiley   +1 more source

Disruption of Radiological Surveillance Following a Global Health Crisis in Resected Lung Cancer

open access: yesThoracic Cancer
Objectives Radiological surveillance after curative‐intent lung cancer resection is essential for early detection of recurrence and second primary tumors. Large‐scale health emergencies can compromise oncologic follow‐up. This study quantifies the impact
Álvaro Fuentes‐Martín   +5 more
doaj   +1 more source

Comparative outcomes of video-assisted thyroidectomy and traditional open surgery: a 5-year analysis of a single center experience

open access: yesBrazilian Journal of Otorhinolaryngology
Objective: This study aimed to evaluate and compare the outcomes of patients undergoing video-assisted thyroidectomy versus those undergoing traditional open surgery.
Kenzo Ohara   +6 more
doaj   +1 more source

MAP: Microblogging Assisted Profiling of TV Shows

open access: yes, 2015
Online microblogging services that have been increasingly used by people to share and exchange information, have emerged as a promising way to profiling multimedia contents, in a sense to provide users a socialized abstraction and understanding of these ...
C. Holotescu   +6 more
core   +1 more source

Integrating Patient‐Reported Quality Measures in Systemic Lupus Erythematosus: Development of the American College of Rheumatology Implementation Guide

open access: yesArthritis Care &Research, EarlyView.
Objective To support high‐quality, patient‐centered care for systemic lupus erythematosus (SLE), the American College of Rheumatology (ACR) developed evidence‐based measures incorporating clinical and patient‐reported outcome measures (PROMs). Using the Consolidated Framework for Implementation Research (CFIR), we conducted semistructured interviews ...
Catherine Nasrallah   +13 more
wiley   +1 more source

Video-assisted sacral nerve stimulation [PDF]

open access: yes, 2018
Background: Sacral nerve simulation (SNS) is an accepted therapy for patients with urinary or bowel dysfunction. However, infection rates are as high as 20% and can result in removal of the expensive device.
Clavien, P.   +3 more
core  

Building a Framework for Sexual and Reproductive Health Care in the Rheumatology Context: Content and Approaches

open access: yesArthritis Care &Research, EarlyView.
People with systemic autoimmune and rheumatic diseases (SARDs) are at higher risk than the general population of experiencing adverse pregnancy and perinatal outcomes such as preeclampsia, intrauterine growth restriction, and maternal and/or fetal death.
Mehret Birru Talabi, Sonya Borrero
wiley   +1 more source

Home - About - Disclaimer - Privacy