Results 201 to 210 of about 5,363,625 (319)

Messenger Use and Video Calls as Correlates of Depressive and Anxiety Symptoms: Results From the Corona Health App Study of German Adults During the COVID-19 Pandemic.

J Med Internet Res
Edler JS, Terhorst Y, Pryss R, Baumeister H, Cohrdes C.   +4 more
europepmc   +1 more source

Versatile CRISPR‐Cas Tools for Gene Regulation in Zebrafish via an Enhanced Q Binary System

Advanced Science, EarlyView.
This study introduces CRISPR‐Q, a transgenic CRISPR‐Cas system leveraging the QFvpr/QUAS binary expression platform in zebrafish. CRISPR‐Q overcomes previous challenges in achieving stable and efficient gene regulation. By enabling precise spatiotemporal control of transcript knockdown (CRISPR‐QKD) and gene activation (CRISPR‐Qa), it provides a ...
Miaoyuan Shi, Weiqi Ge, Changheng Li, Bin Liu, Xiaoyi Deng, Chengjie Liu, Meijun Zheng, Pu Zhang, Lei Li, Ying Guo, Yunqi Han, Yu Yang, Yanxun V. Yu, Youngnam N. Jin   +13 more
wiley   +1 more source

Amyloid β Instigates Cardiac Neurotrophic Signaling Impairment, Driving Alzheimer's Associated Heart Disease

Advanced Science, EarlyView.
This research identified cardiac amyloid pathology, neurotrophic factor depletion, and reduced myocardial nerve function in a transgenic model of cerebral amyloidosis (Tg2576), Aβ‐challenged cardiomyocytes, and in human AD heart tissue. These findings carry significant diagnostic and therapeutic implications, emphasizing the role of neuro‐signaling ...
Andrea Elia, Rebecca Parodi‐Rullan, Rafael Vazquez‐Torres, Ashley Carey, Huaqing Zhao, Sabzali Javadov, Silvia Fossati   +6 more
wiley   +1 more source

Multi-Site Videoconferencing for the UK e-Science Programme [PDF]

, 2002
Booth, Stephen, Brooke, John, Caldwell, Kate, Carver, Liz, Daw, Michael, De, Roure David, Flavell, Alan, Galvez, Philippe, Gilmore, Brian, Hughes, Henry, Juby, Ben, Judson, Ivan, Miller, Jim, Newman, Harvey, Osland, Chris, Rogers, Sue   +15 more
core  

Lipid Droplet‐Localized Spindle Apparatus Coiled‐Coil Protein 1 Regulates Lipid Droplet Distribution

Advanced Science, EarlyView.
SPDL1‐L, a long isoform of SPDL1, is identified as a bona fide lipid droplet‐associated protein that acts as a dynein adaptor to drive perinuclear clustering of lipid droplets. By linking lipid droplets to the microtubule network, SPDL1‐L extends the function of SPDL1 beyond mitosis and contributes to lipid droplet organization and nuclear remodeling ...
Honggang Su, Huimin Pan, Yaqiang Liu, Wei Wang, Yang Jiao, Yumo Hang, Xiahe Huang, Yong E. Zhang, Yuhang Chen, Mei Ding, Xun Huang   +10 more
wiley   +1 more source

Video call program for intensive care patients and their families during the COVID-19 pandemic: A retrospective study. [PDF]

Saudi Med J
AlHumedi H, Al-Dorzi HM, Aldawood A, Almatroud A, Aldawsari M, Banu Khan H, Burrows V, Alanazi SA, Naidv B, January E, Al Zayer S, Yeni Z, Marhoun S, Khoutani H, Maghrabi S, AlZighaibi S, Rabeeah F, Alanazi S, Alghamdi H, Aleem Atassi A, Alkathaami A, Arabi YM.   +21 more
europepmc   +1 more source

Design of a Cobalt‐Free Maraging Steel with Ultra‐High Strength of 2.3 GPa Through Additive Manufacturing

Advanced Science, EarlyView.
A computationally designed, cobalt‐free maraging steel tailored for additive manufacturing achieves an ultra‐high tensile strength of 2.3 GPa with 5.7% elongation. This exceptional strength‐ductility synergy stems from high‐density core‐shell Ni3Ti/NiAl nanoprecipitates, a crack‐resistant composition, and a fine equiaxed grain structure enabled by ...
Hu Li, Shubo Gao, Liming Tan, Weiming Ji, Liuliu Han, Kun Zhou, Yong Liu   +6 more
wiley   +1 more source

Big data approaches to bovine bioacoustics: a FAIR-compliant dataset and scalable ML framework for precision livestock welfare. [PDF]

Front Big Data
Kate M, Neethirajan S.
europepmc   +1 more source

The Mitochondrial Guardian α‐Amyrin Mitigates Alzheimer's Disease Pathology via Modulation of the DLK‐SARM1‐ULK1 Axis

Advanced Science, EarlyView.
Dietary habits play a key role in chronic diseases, and higher annual consumption of fruit and vegetable may lower risk of dementia. Artificial intelligence predicts the lipid‐like compound α‐Amyrin (αA) from plants with edible peels as a drug candidate against Alzheimer's disease.
Shu‐Qin Cao, Juan Ignacio Jiménez‐Loygorri, Yunguang Qiu, You Jung Kang, Khanh Van Do, Annabel E. Smith, Junjie Huang, Jun‐ping Pan, Lipeng Mao, Ang Li, Hangge Yang, Yahyah Aman, Maria Jose Donate Lagartos, Sofie Hindkjær Lautrup, Anbin Chen, Kristina Xiao Liang, Hailong Zhang, Juan Yi, Xurui Jin, Tin Cho Cheung, Olympia Apokotou, Florentia Papastefanaki, Rebecca Matsas, William A. McEwan, Feixiong Cheng, Hansang Cho, Guobing Chen, Huanxing Su, Konstantinos Palikaras, Oscar Junhong Luo, Qian Hua Zhao, Ding Ding, Cornelia van Duijn, Nektarios Tavernarakis, Patricia Boya, Tewin Tencomnao, Evandro F. Fang   +36 more
wiley   +1 more source

Managing apnoea in trauma victims: the potential for dispatcher-assisted airway handling - a narrative review. [PDF]

Scand J Trauma Resusc Emerg Med
Imbriaco G, D'arrigo S, Limonti F, Rehn M, Cucino A.   +4 more
europepmc   +1 more source