Results 41 to 50 of about 32,650 (259)

Calcium Shock Enables Efficient and Programmable Particle Delivery for Genome Editing Applications

Advanced Science, EarlyView.
Classical transfection and transduction are inefficient, particularly with confluent cells and organoids, and lack cell type‐specific programmability. This study presents calcium shock (CaSh), a method that dramatically improves particle delivery into single cells, colonies, and organoids.
Nicole Vo, Lorena de Oñate, Maximillian Frank, Xian Hu, Sophie M. Blackburn, Dana V. Foss, Jasmine Villegas, Kunica Asija, Dirk Hockemeyer, Hongxia Fu, Raymond J. Monnat, Ross C. Wilson, Benjamin S. Freedman   +12 more
wiley   +1 more source

Application of 3D scanning technology in Royal Malaysian Air Force Industrial Revolution 4.0‐based aircraft maintenance

IET Networks, EarlyView., 2022
Abstract 3D scanning is rapidly becoming a key maintenance tool. Aerospace was a pioneer in adopting 3D scanning technology because aircraft manufacture and maintenance require precision. Monitoring deterioration, removing components for maintenance, and verifying covert operations are not practical or helpful without technology.
T. Nanthakumaran Thulasy, Puteri N. E. Nohuddin, Istas Fahrurrazi Nusyirwan, Mohd Hanafi Ahmad Hijazi, Musaddak Maher Abdul Zahra   +4 more
wiley   +1 more source

Facilities and Standards [PDF]

, 1969
published or submitted for ...
Johnson, Marvin R.A.
core  

Amyloid β Instigates Cardiac Neurotrophic Signaling Impairment, Driving Alzheimer's Associated Heart Disease

Advanced Science, EarlyView.
This research identified cardiac amyloid pathology, neurotrophic factor depletion, and reduced myocardial nerve function in a transgenic model of cerebral amyloidosis (Tg2576), Aβ‐challenged cardiomyocytes, and in human AD heart tissue. These findings carry significant diagnostic and therapeutic implications, emphasizing the role of neuro‐signaling ...
Andrea Elia, Rebecca Parodi‐Rullan, Rafael Vazquez‐Torres, Ashley Carey, Huaqing Zhao, Sabzali Javadov, Silvia Fossati   +6 more
wiley   +1 more source

Assessing Comfort and Safety in Use of Elevators’ Human–Machine Interaction Devices

Buildings
Elevators are essential for accessibility and play a key role in a building’s functionality. Normally mass-produced and purchased from catalogs, elevators require thoughtful integration into architectural design to meet ergonomic, aesthetic, and safety ...
Giovanni Perrucci, Marco Costa, Elena Giacomello, Dario Trabucco   +3 more
doaj   +1 more source

Extending the 5S Framework of Digital Libraries to support Complex Objects, Superimposed Information, and Content-Based Image Retrieval Services [PDF]

, 2010
Advanced services in digital libraries (DLs) have been developed and widely used to address the required capabilities of an assortment of systems as DLs expand into diverse application domains.
Archer, David, Delcambre, Lois, Fox, Edward, Goncalves, Marcos, Kozievitch, Nadia, Leidig, Jonathan, Murthy, Uma, Torres, Ricardo, Yang, Seungwon   +8 more
core   +1 more source

Phenotypic redshifts with self-organizing maps: A novel method to characterize redshift distributions of source galaxies for weak lensing [PDF]

, 2019
Wide-field imaging surveys such as the Dark Energy Survey (DES) rely on coarse measurements of spectral energy distributions in a few filters to estimate the redshift distribution of source galaxies.
Abbott, TMC, Alarcon, A, Allen, S, Amon, A, Annis, J, Avila, S, Bechtol, K, Bernstein, GM, Bridle, SL, Brooks, D, Buchs, R, Buckley-Geer, E, Burke, DL, Carnero Rosell, A, Carretero, J, Castander, FJ, Cawthon, R, Choi, A, Collaboration, DES, D Andrea, CB, da Costa, LN, Davis, C, De Vicente, J, DeRose, J, Desai, S, Diehl, HT, Doel, P, Drlica-Wagner, A, Eifler, TF, Evrard, AE, Flaugher, B, Fosalba, P, Frieman, J, Garcia-Bellido, J, Gaztanaga, E, Gruen, D, Gruend, RA, Gschwend, J, Gutierrez, G, Hartley, WG, Hollowood, DL, Honscheid, K, James, DJ, Kind, M Carrasco, Kuehn, K, Kuropatkin, N, Lima, M, Lin, H, Maia, MAG, March, M, Marshall, JL, Masters, DC, Melchior, Peter M, Menanteau, F, Miquel, R, Myles, J, Ogando, RLC, Plazas, AA, Roodman, A, Rykoff, ES, Sanchez, C, Sanchez, E, Scarpine, V, Serrano, S, Sevilla-Noarbe, I, Smith, M, Soares-Santos, M, Sobreira, F, Suchyta, E, Swanson, MEC, Tarle, G, Thomas, D, Troxel, MA, Vikram, V, Wechsler, RH   +74 more
core   +2 more sources

NPM1 Mediates mRNA Sorting into Extracellular Vesicles via Specific RNA Motif Binding and Phase Separation

Advanced Science, EarlyView.
NPM1 selectively sorts specific mRNAs into extracellular vesicles (EVs) by recognizing RNA motifs and forming phase‐separated condensates. These mRNA cargos—including EGFR—are then loaded via multivesicular bodies. This active sorting pathway, validated in EVs derived from both lung cancer cells and patient serum, reveals a specific mechanism for ...
Kaixiang Zhang, Gaoge Sun, Xiangzheng Liu, Shuai Zuo, Pengyuan Wang, Boxiao Zhan, Zhi John Lu, Hang Yin, Ying Zhang   +8 more
wiley   +1 more source

Audiovisual industry and the structural factors of the television crisis

Matrizes, 2017
This article analyzes the current state of traditional television financing resources, detecting a critical situation in its three main sources (advertising, signatures and service charges).
Giuseppe Richeri
doaj  

Libraries and Museums in the Flat World: Are They Becoming Virtual Destinations? [PDF]

, 2006
In his recent book, “TheWorld is Flat”, Thomas L. Friedman reviews the impact of networks on globalization. The emergence of the Internet, web browsers, computer applications talking to each other through the Internet, and the open source software, among
Tonta, Yaşar
core   +1 more source